Past Seminars

Seminars 2023

March 29, 2023
Stuart Newfeld, Arizona State University. “TGF-beta signaling regulates insulin expression in adult females” (Inaba, Host). Hybrid

April 19, 2023
Orna Cohen-Fix, The National Institutes of Health. “The Centriculum: a centrosome-associated membrane that affects centrosome structure and function” (Terasaki, Host). Hybrid

May 24, 2023
Jessica Rouge, UConn, Storrs. “Overcoming biological barriers to nucleic acid delivery using enzymatically released DNA surfactant conjugates” (Smilowitz, Host). Hybrid

June 7, 2023
Juliette Fedry, Utrecht University. “Visualization of translation and protein biogenesis at the ER membrane”. (Jaffe, Host). Hybrid

June 9, 2023
Hitoshi Takizawa, Kumamoto University, Japan. “A crosstalk between microbial signals and hematopoiesis”. (Oguro, Host). Hybrid

July 10, 2023
Goro Yoshizaki, Tokyo University of Marine Science & Technology. "Manipulation of germ-line stem cell in fish: Can mackerel produce bluefin tuna gametes?"(Inaba, Host). Hybrid

October 18, 2023
Kim Jonas, King's College, London. "Understanding the role(s) of gonadotrophin hormone receptor oligomerization in reproductive function and aging". (Jaffe, Host). Hybrid

November 8, 2023
Sei Yoshida, Nankai University, Tianjin, China.  "Macropinocytosis-AKT/mTORC1 pathway in human health and diseases". (Inaba Oguro, Host). Hybrid

Seminars 2022

February 16, 2022
Andrew Collins, Bio-Rad Laboratories. "The Power of Partitioning: Droplet Digital PCR (ddPCR)" (Lowther, Host). Web Presentation.

February 21, 2022
Amanda Kallen, Yale University. Joint seminar with the Department of Obstetrics and Gynecology. "From genomic junk to rising stars: novel, noncoding RNA mediators of ovarian aging” (Jaffe and Brewer, co-hosts). Webex.

March 23, 2022
Francesca Duncan, Northwestern University. "The first to age: mechanisms of ovarian aging". Joint seminar with the center on aging (Mehlmann and Kuchel, co-Hosts). Webex.

April 7, 2022
Indra Chandrasekar, South Dakota Univ., “Unique functional role(s) for MYH9 in two distinct kidney cell types: possible answers to MYH9 related disease” (Terasaki w/Trivedi, Nephrology). Webex.

April 13, 2022
Bill Skarnes, JAX, “Precise, high-efficiency editing of stem cells to probe human biology and model disease” (Oguro, Host). Webex.

June 21, 2022
Nathaniel Ponvert, “Investigation into membrane voltage polarization during sperm/egg fusion in Arabidopsis” (Jaffe, Host).

September 21, 2022
Shinya Matsuda, University of Basel, CHE. “Investigating tissue patterning and growth by a morphogen gradient using novel synthetic protein binder tools” (Inaba, Host). Webex.

October 19, 2022
Chris Schaffer, Cornell University. "Insight into cerebral vascular function, hemodynamics, and immune interactions by intravital multiphoton imaging" (Murphy, Host). Hybrid.

October 26, 2022
Jianjun Sun, UConn, Storrs.“ Drosophila model for interrogating ovulation mechanism and identifying novel contraceptive compounds” (Inaba, Host). Webex.

Seminars 2021

March 17, 2021
Alexandra Naba, University of Illinois at Chicago. "Exploring the roles of the extracellular matrix in health and disease using proteomics"(Murphy, Host). Webex.

March 31, 2021
Tim O'Connell, University of Minnesota. “Novel alpha-1 adrenergic receptor antagonist without cardiovascular side-effects for the treatment of hypertension” (Dodge-Kafka, Host). Webex.

October 13, 2021
Georgia Zarkada, Yale School of Medicine. “Endothelial cell heterogeneity during sprouting angiogenesis” (Shapiro, Host). Webex.

October 20, 2021
Ching Lau, Jax and Connecticut Children's Medical Center. “Developing precision medicine for pediatric cancers: challenges and opportunities.” (Smilowitz, Host).

Seminars 2020

January 29, 2020
Olga Anczukȯw, Jackson Labs. "Misregulation of Splicing Factors in Breast Cancer" (Guo-Hua Fong, Host)

March 4, 2020
Dianne Cox, Albert Einstein College of Medicine. “Touched by a macrophage: macrophagetumor cell communication in tumor progression”(Linda Shapiro, Host)

March 18, 2020 (Postponed)
Eloy Bejarano, Tufts University. “Detrimental Impact of Glycative Stress on Intercellular Communication and Autophagy” (Rachel Norris, Host)

April 15, 2020 (Postponed)
Steve Rogers, University of North Carolina.“Control of mechanosensation in Drosophila by the microtubule acetylase dTAT ” (Mark Terasaki, Host)

April 29, 2020 (Postponed)
Chris Schaffer, Cornell University. (Pat Murphy, Host)

May 6, 2020 (Postponed)
Tim O'Connell, University of Minnesota. (Kim Dodge-Kafka, Host)

Seminars 2019

February 6, 2019
Vito Mennella, University of Toronto. “Super-resolution imaging drives mechanism, discovery, and diagnosis of rare diseases” (Rindy Jaffe, Host)

March 27, 2019
Richard Cheney, University of North Carolina. “Cellular and organismal functions of myosin-X, a filopodial motor protein” (Mark Terasaki, Host)

April 3, 2019
Hideyuki Oguro, Jackson Laboratory. “Systemic regulation of hematopoietic stem cell division and mobilization” (Rindy Jaffe, Host)

May 29, 2019
Jean-Ju Chung, Yale University.“A novel pH-dependent Ca2+ sensor that regulates CatSper channel activity and sperm motility” (Lixia Yue, Host).

August 30, 2019
Li Gan, Weill Cornell Medicine.“Proteostasis and Inflammation: New Insights and Therapeutic Strategies in Neurodegeneration”(Pat Murphy, Host).

September 25, 2019
Michael Buszczak, University of Texas, Southwestern. "Genetic dissection of germ cell differentiation and function” (Mayu Inaba, Host). 

October 2, 2019
Aylin Hanyaloglu, Imperial College London. "Multi-dimensional programming of G protein-coupled receptor signaling; mechanisms and applications" (Rindy Jaffe, Host)

October 23, 2019
Mariana Wolfner, Cornell University. "Triggers of egg activation: using Drosophila to identify conserved and unique features" (Rindy Jaffe, Host)

November 27, 2019
Bela Anand-Apte, Cleveland Clinic. "New insights into diabetic retinopathy and blood barrier disruption" (Guo-Hua Fong, Host)

Seminars 2018

February 7, 2018
Duygu Ozpolat, Marine Biological Laboratory, Woods Hole. "Tracing the cellular origins of germline formation and regeneration in the annelids." (Mark Terasaki, Host)

April 4, 2018
John Lamar, Albany Medical College. "The Hippo-YAP/TAZ pathway and its role in cancer progression and metastasis." (Pat Murphy, Host)

May 9, 2018
Yukiko Yamashita, University of Michigan. "Asymmetric stem cell division and germ cell immortality." (Mayu Inaba, Host)

June 13, 2018
Rong Wang, UCSF. "Notch Signaling in Arterial and Venous Programming and Reprogramming." (Pat Murphy, Host)

September 12, 2018
Valentina Greco, Yale University. "Principles of tissue dynamics and function captured by live imaging." (Mayu Inaba, Host)

October 3, 2018 (9 a.m., L7040A, joint with skeletal biology group)
Laurence Legeai-Mallet, University of Paris. "Therapeutic Approaches for FGFR3-related disorders." (Leia Shuhaibar and Laurinda Jaffe, Hosts)

October 3, 2018
Geoffrey Pitt, Cornell University. "Lessons from the heart: New insights into physiology from ion channelopathies." (Lixia Yue, Host)

November 28, 2018
Andrew Lichtman, Brigham & Women's Hospital. "Immune Checkpoints in the Cardiovascular System." (Annabelle Rodriguez-Oquendo, Host)

December 5, 2018
Mario Delmar, New York University. "Debunking the concept of one gene-one disease in inheritable sudden death." (Lixia Yue, Host)

December 12, 2018 (joint with skeletal biology group)
Julian Lui, National Institutes of Health. "Dissecting physiological and pathophysiologically mechanisms in the skeletal growth plate." (Leia Shuhaibar and Laurinda Jaffe, Hosts)

Seminars 2017

December 13, 2017
Steven L'Hernault, Emory University. "Looks Aren't Everything: What Nematode Sperm are Teaching Us about Conserved Aspects of Fertilization."

November 29, 2017
Doug Tilley, Temple University. "Fine -Tuning ß2-adernergic Receptor Signaling for Cardiac Repair."

October 11, 2017
James Pru, Washington State University. "PGRMC1 and PGRMC2  Functions in Female Fertility and Disease."

September 20, 2017
Diane Duffy, Eastern Virginia Medical School Norfolk, VA. "Angiogenesis in the Ovulatory Follicle: Opportunities for Novel Contraceptive Development."

July 31, 2017
Nita Maihle, Medical College of Georgia. "EGF/HER Receptor Isoforms: Form, Function, and Clinical Implications."

May 24, 2017
Lane Christenson, University of Kansas Medical Center. "Extracellular Vesicles and Cell to Cell Communication in Ovarian Follicles.”

April 18, 2017
Jim Hainfeld, Nanoprobes, Inc., Yaphank, NY, "Biography of a Nanoparticle."

April 12, 2017
Cahir O'Kane, University of Cambridge, "Roles of spastic paraplegia proteins in axonal ER organisation in Drosophila."

March 22, 2017
Sarah Xin Zhang, SUNY, Buffalo, "Protein homeostasis and ER stress in Retinal Angiogenesis and Vascular Repair."

Seminars 2016

October 21, 2016
Jan Ellenberg, European Molecular Biology Laboratory Heidelberg, Germany, "Imaging the assembly of protein complexes and the dynamics of protein."

September 14, 2016
Paul Robson and Leah Kaye, Jackson Laboratory, "Evolution and Development of the Human Primitive Syncytium: Determining the impact of the emergence of chorionic gonadotropin on FSH, LH, and TSH using a humanized mouse."

June 9, 2016
Hideyuki Oguro, University of Texas Southwestern Medical Center at Dallas, "Activation of hematopoietic stem cells by systemic signals."

May 11, 2016
Melissa Rolls, Pennsylvania State University, "Microtubule organization in axons versus dendrites."

April 26, 2016
Yanxun Yu, Brandeis University, MA. "From sensation to adaptation: new insights into thermosensation and thermal acclimation."

March 29, 2016
Mayu Inaba, University of Texas Southwestern Medical Center at Dallas. "Asymmetric stem cell division in Drosophila germline stem cells."

February 3, 2016
Elyse Donaubauer, Washington State University. "Phospho-regulation of Y-Box binding protein 1 (YB1) in response to FSH stimulation in ovarian granulosa cells promotes induction of ERK-dependant target genes."

January 29, 2016
Justin Cotney, UConn Health. “Functional Genomics Approaches to Understand Human Development, Evolution, and Disease.” Joint seminar with the Skeletal Biology and Regeneration Graduate Program.

January 22, 2016
Alexei Evsikov, Morsani College of Medicine, USF Health, University of South Florida. “Emerging genetic networks in mammalian egg-to-embryo transition.”

January 19, 2016
Maria Rubio, University of Pittsburgh. "Target- and input-dependent organization of AMPA and NMDA receptors in synaptic connections of the cochlear nucleus." Joint seminar with the Department of Neuroscience.

January 13, 2016
Evan Smoak, University of Pennsylvania. "Transgenerational Inheritance of Centromere Identity in the Mammalian Oocyte."

Seminars 2015

October 14, 2015
Frank S. Menniti, Mnemosyne and Pharmaceuticals, Inc. "Ketamine and depression: The most important psychiatric discovery in half a century." Joint seminar with the Department of Neuroscience.

October 7, 2015
JoAnne Richards, Baylor College of Medicine. "From ovulation to ovarian cancer -an unexpected journey." Joint seminar with the Department of Physiology and Neurology, Storrs.

September 30, 2015
Xue-Jun Li, Department of Neuroscience, UConn Health. "Elucidating mechanisms of motor neuron development and degeneration using human pluripotent stem cells.”

July 29, 2015
Rafael Fissore, UMASS-Amherst. "Oddities in the regulation of Ca2+ homeostasis in mouse oocytes and eggs."

June 23, 2015
Simon Lane, University of Southampton, UK. "The meiotic checkpoint in mouse oocytes: A duel role in protecting genomic integrity."

May 12, 2015
Ted Rassmussen, UConn Storrs. "Examining the epigenetics of preimplantation embryos and pluripotent stem cells."

April 28, 2015
Hugh J. Clarke, McGill University. "Getting in touch with the neighbors: A new model of germ line-somatic communication in the ovarian follicle."

April 21, 2015
Jerid W. Robinson, Emory University. "Parathyroid hormone and T cells in Bone: The Jekyll and Hyde of osteoimmunology."

April 7, 2015
Virgil Muresan, Rutgers, NJ Medical School. “Long-distance transport in neurons revisited: An unexplored function of the endoplasmic reticulum.”

March 19, 2015
Diego Bohórquez , Duke University Medical Center. "Where the Gut Meets the Brain."

March 10, 2015
Cahir O'Kane, University of Cambridge. "Roles of Drosophila spastic paraplegia genes in organisation of  axonal endoplasmic reticulum."

January 27, 2015
Jim Pru, Washington State University. "Mechanisms of Endometrial Regeneration."

Seminars 2014

October 28, 2014
Mary Hunzicker-Dunn. Washington State University. "FSH signaling in ovarian granulosa cells: How PKA hijacks other pathways to regulate gene expression." Joint seminar with the Endocrine Scholar Lecture Series.

October 9, 2014
Peng Jin. Emory University School of Medicine. "Molecular basis of Fragile X-related disorders." Joint seminar with the Department of Genetics and Developmental Biology.

May 16, 2014
Viacheslav Nikolaev. University of Goettingen. "Imaging compartmentalized pools of cAMP to understand heart physiology and disease." Joint seminar with the Department of Cell Biology and Center for Vascular Biology.

April 29, 2014
Giulia Vigone. University of Pavia."The road towards follicle developmental competence: Cumulus cell markers and 3D in vitro follicle culture."

April 15, 2014
Rachael Norris. Fred Hutchinson Cancer Research Center. "Connexin43 Phosphorylation: Tales from the C-terminal tail."

February 28, 2014
Marina Freudzon. Yale University. "The unexpected roles of Langerhans cells in cutaneous carcinogenesis."

Seminars 2013

November 12, 2013
Natalie Matijescukova. Veterinary Research Institute, Czech Republic. "Oocyte spindle dancing to the cortex."

October 17, 2013
Rick H. Cote. Molecular, Cellular and Biomedical Sciences, University of New Hampshire – Joint Seminar with the Department of MMSB. "Structural basis for the activation of cGMP phosphodiesterase during the first steps in vision."

June 4, 2013
Emre Seli, Yale University. "Translational regulation of gene expression during oogenesis: the role of embryonic poly(A) binding protein."

May 9, 2013
Carmen Dessauer, University of Texas-Houston. "Spatial constraints of cAMP signaling: the next dimension in adenylyl cyclase regulation."

March 26, 2013
Yijun Ruan, Jackson Labs, Farmington, CT. "ChIA-PET for 3D chromatin interaction architecture, transcription regulation, and disease."

January 9, 2013
Carmen Williams, National Institute of Health/National Institute of Environmental Health Sciences, Research Triangle Park, NC. "Outside-in calcium signaling is required for egg activation."