A reference human induced pluripotent stem cell line for large-scale collaborative studies
Caroline B Pantazis, Andrian Yang, Erika Lara, Justin A McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kanaujiya, Jizhong Zou, David Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, Constance Medura, Christopher Tompkins, Stephen Hughes, Marianita Santiana, Faraz Faghri, Mike A Nalls, Daniel Vitale, Shannon Ballard, Yue A Qi, Daniel M Ramos, Kailyn M Anderson, Julia Stadler, Priyanka Narayan, Jason Papademetriou, Luke Reilly, Matthew P Nelson, Sanya Aggarwal, Leah U Rosen, Peter Kirwan, Venkat Pisupati, Steven L Coon, Sonja W Scholz, Theresa Priebe, Miriam Öttl, Jian Dong, Marieke Meijer, Lara JM Janssen, Vanessa S Lourenco, Rik van der Kant, Dennis Crusius, Dominik Paquet, Ana-Caroline Raulin, Guojun Bu, Aaron Held, Brian J Wainger, Rebecca MC Gabriele, Jackie M Casey, Selina Wray, Dad Abu-Bonsrah, Clare L Parish, Melinda S Beccari, Don W Cleveland, Emmy Li, Indigo VL Rose, Martin Kampmann, Carles Calatayud Aristoy, Patrik Verstreken, Laurin Heinrich, Max Y Chen, Birgitt Schüle, Dan Dou, Erika LF Holzbaur, Maria Clara Zanellati, Richa Basundra, Mohanish Deshmukh, Sarah Cohen, Richa Khanna, Malavika Raman, Zachary S Nevin, Madeline Matia, Jonas Van Lent, Vincent Timmerman, Bruce R Conklin, Katherine Johnson Chase, Ke Zhang, Salome Funes, Daryl A. Bosco, Lena Erlebach, Marc Welzer, Deborah Kronenberg-Versteeg, Guochang Lyu, Ernest Arenas, Elena Coccia, Lily Sarrafha, Tim Ahfeldt, John C Marioni, William C Skarnes, Mark R Cookson, Michael E Ward, Florian T Merkle
Cell Stem Cell. 2022;29(12):1685–1702
Generation of hematopoietic stem and progenitor cells from human pluripotent stem cells
Hideyuki Oguro
Methods Mol Biol. 2019;2048:245-257
The roles of cholesterol and its metabolites in normal and malignant hematopoiesis
Hideyuki Oguro
Front Endocrinol. 2019;10:204
27-hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy
Hideyuki Oguro*, Jeffrey G McDonald, Zhiyu Zhao, Michihisa Umetani, Philip W Shaul, Sean J Morrison* (*co-corresponding author)
J Clin Invest. 2017;127(9):3392-3401
Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal
Melih Acar, Kiranmai S Kocherlakota, Malea M Murphy, James G Peyer, Hideyuki Oguro, Christopher N Inra, Christabel Jaiyeola, Zhiyu Zhao, Katherine Luby-Phelps, Sean J Morrison
Nature. 2015;526(7571):126-130
Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy
Daisuke Nakada, Hideyuki Oguro, Boaz P Levi, Nicole Ryan, Ayumi Kitano, Yusuke Saitoh, Makiko Takeichi, George R Wendt, Sean J Morrison
Nature. 2014;505(7484):555-558
Lung bone marrow-derived hematopoietic progenitor cells enhance pulmonary fibrosis
Taku Nakashima, Tianju Liu, Hongfeng Yu, Lin Ding, Matthew Ullenbruch, Biao Hu, Zhe Wu, Hideyuki Oguro, Sem H Phan
Am J Respir Crit Care Med. 2013;188(8):976-984
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors
Hideyuki Oguro, Lei Ding, Sean J Morrison
Cell Stem Cell. 2013;13(1):102-116
Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes
Hideyuki Oguro, Jin Yuan, Satomi Tanaka, Satoru Miyagi, Makiko Mochizuki-Kashio, Hitoshi Ichikawa, Satoshi Yamazaki, Haruhiko Koseki, Hiromitsu Nakauchi, Atsushi Iwama
J Exp Med. 2012;209(3):445-454
Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells
Takaaki Konuma, Shunsuke Nakamura, Satoru Miyagi, Masamitsu Negishi, Tetsuhiro Chiba, Hideyuki Oguro, Jin Yuan, Makiko Mochizuki-Kashio, Hitoshi Ichikawa, Hiroyuki Miyoshi, Miguel Vidal, Atsushi Iwama
Exp Hematol. 2011;39(6):697-709.e5
Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells
Jin Yuan, Masahiro Takeuchi, Masamitsu Negishi, Hideyuki Oguro, Hitoshi Ichikawa, Atsushi Iwama
Leukemia. 2011;25(8):1335-1343
Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice
Tetsuhiro Chiba, Atsuyoshi Seki, Ryutaro Aoki, Hitoshi Ichikawa, Masamitsu Negishi, Satoru Miyagi, Hideyuki Oguro, Atsunori Saraya, Akihide Kamiya, Hiromitsu Nakauchi, Osamu Yokosuka, Atsushi Iwama
Hepatology. 2010;52(3):1111-1123
Role of the polycomb group proteins in hematopoietic stem cells
Takaaki Konuma, Hideyuki Oguro, Atsushi Iwama
Dev Growth Differ. 2010;52(6):505-516
FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells
Takeaki Sugawara, Hideyuki Oguro, Masamitsu Negishi, Yohei Morita, Hitoshi Ichikawa, Toru Iseki, Osamu Yokosuka, Hiromitsu Nakauchi, Atsushi Iwama
Exp Hematol. 2010;38(8):696-706
Depletion of Dnmt1-associated protein 1 triggers DNA damage and compromises the proliferative capacity of hematopoietic stem cells
Tomoe Koizumi, Masamitsu Negishi, Shunsuke Nakamura, Hideyuki Oguro, Kaneshige Satoh, Masaharu Ichinose, Atsushi Iwama
Int J Hematol. 2010;91(4):611-619
Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1
Hideyuki Oguro, Jin Yuan, Hitoshi Ichikawa, Tomokatsu Ikawa, Satoshi Yamazaki, Hiroshi Kawamoto, Hiromitsu Nakauchi, Atsushi Iwama
Cell Stem Cell. 2010;6(3):279-286
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL
Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito, Kana Miyamoto, Hiroki Yoshiwara, Kentaro Hosokawa, Yuka Nakamura, Yumiko Gomei, Hiroko Iwasaki, Yasuhide Hayashi, Yumi Matsuzaki, Keiko Nakayama, Yasuo Ikeda, Akira Hata, Shigeru Chiba, Keiichi I Nakayama, Toshio Suda
Genes Dev. 2008;22(8):986-991
Life and death in hematopoietic stem cells
Hideyuki Oguro, Atsushi Iwama
Curr Opin Immunol. 2007;19(5):503-509
Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo
Toshinao Oyama, Kenichi Harigaya, Ablimit Muradil, Katsuto Hozumi, Sonoko Habu, Hideyuki Oguro, Atsushi Iwama, Kenji Matsuno, Reiko Sakamoto, Mitsuharu Sato, Nobuaki Yoshida, Motoo Kitagawa
Proc Natl Acad Sci U S A. 2007;104(23):9764-9769
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
Hideyuki Oguro, Atsushi Iwama, Yohei Morita, Takehiko Kamijo, Maarten van Lohuizen, Hiromitsu Nakauchi
J Exp Med. 2006 Oct 2;203(10):2247-2253
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells
Masanori Sakaguchi, Tetsuro Shingo, Takuya Shimazaki, Hirotaka James Okano, Mieko Shiwa, Satoru Ishibashi, Hideyuki Oguro, Mikiko Ninomiya, Toshihiko Kadoya, Hidenori Horie, Akira Shibuya, Hidehiro Mizusawa, Françoise Poirier, Hiromitsu Nakauchi, Kazunobu Sawamoto, Hideyuki Okano
Proc Natl Acad Sci U S A. 2006;103(18):7112-7117
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon
Satoru Miyagi, Masazumi Nishimoto, Tetsuichiro Saito, Mikiko Ninomiya, Kazunobu Sawamoto, Hideyuki Okano, Masami Muramatsu, Hideyuki Oguro, Atsushi Iwama, Akihiko Okuda
J Biol Chem. 2006;281(19):13374-13381
Polycomb gene product Bmi-1 regulates stem cell self-renewal
Hiromitsu Nakauchi, Hideyuki Oguro, Masamitsu Negishi, Atsushi Iwama
Ernst Schering Res Found Workshop. 2005;(54):85-100
Epigenetic regulation of hematopoietic stem cell self-renewal by polycomb group genes
Atsushi Iwama, Hideyuki Oguro, Masamitsu Negishi, Yuko Kato, Hiromitsu Nakauchi
Int J Hematol. 2005;81(4):294-300
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
Atsushi Iwama*, Hideyuki Oguro*, Masamitsu Negishi, Yuko Kato, Youhei Morita, Hiroko Tsukui, Hideo Ema, Takehiko Kamijo, Yuko Katoh-Fukui, Haruhiko Koseki, Maarten van Lohuizen, Hiromitsu Nakauchi (*co-first author)
Immunity. 2004;21(6):843-851