UConn Health · Center for Molecular Oncology
Our Faculty
Meet the physician-scientists and researchers driving molecular oncology discovery at UConn Health — from bench to bedside.
Faculty Members
Endocrine Tumors · Cyclin D1 Oncogene · Breast Cancer
Pathogenesis of parathyroid and other endocrine tumors, and role of the cyclin D1 oncogene in neoplasia, including breast cancer.
Colorectal Cancer · DNA Mismatch Repair · Organoid Models
The molecular biology of colorectal cancer. Understanding the functions of the DNA mismatch repair system affected during tumorigenesis using biochemical, cell culture and human organoid models.
Bone Remodeling · Tumor Microenvironment · Metastasis
Study of non-collagen matrix proteins in normal bone remodeling and the impact of microenvironment on tumor development and metastasis.
Gastrointestinal Cancer · Toxicogenomics · Environmental Carcinogenesis
Pathogenesis of gastrointestinal cancer, toxicogenomics, mouse tumor models, environmental carcinogenesis, altered signaling pathways in cancer cells.
Bone Tumors · Tumor Suppressor Genes · Paget’s Disease
Pathogenesis of bone tumors, the role of tumor suppressor genes in neoplasia and development. Genetics of Paget’s disease of bone.
Craniofacial Tumors · HRPT2/CDC73 Tumor Suppressor
Pathogenesis of craniofacial tumors and the role of the HRPT2/CDC73 tumor suppressor gene in neoplasia.
GI Inflammation · Lipid Metabolism · Microbiome
Pathogenesis of gastrointestinal inflammation and cancer, mouse tumor models, the role of lipid metabolism, microbiome, nutritional intervention.
Lynch Syndrome · CRISPR-Cas Gene Editing · DNA Repair
Modeling Lynch syndrome associated DNA mismatch repair gene variants in human embryonic stem cells using CRISPR-Cas gene editing. Functional testing of engineered cell lines for better stratification of Lynch syndrome patients.
Iron Metabolism · Breast Cancer · Nanomaterials
Molecular and cell biology of iron metabolism in breast cancer and other malignancies. Investigating the use of nanomaterials as anticancer agents.
Connect With Our Faculty
Interested in research opportunities or collaborations with the Center for Molecular Oncology? We welcome inquiries from students, trainees, and colleagues.