Metabolites augment oxidative stress to sensitize antibiotic-tolerant Staphylococcus aureus to fluoroquinolones
Batchelder, Jonathan I; Taylor, Andrew J; Mok, Wendy W K mBio 2024 October; e02714-24
Agar and Agarose Used for Staphylococcus aureus Biofilm Cultivation Impact Fluoroquinolone Tolerance
Power, Angela D; Mok, Wendy W K Journal of Applied Microbiology 2024 August; 135(8):lxae191
Metabolic and Transcriptional Activities Underlie Stationary-phase Pseudomonas aeruginosa Sensitivity to Levofloxacin
Hare, Patricia J; Gonzalez Juliet R; Quelle, Ryan M; Wu, Yi I.; Mok, Wendy W K Microbiology Spectrum 2024 January; 12(1):e0356723
Lab Culture: How do Scientists Grow and Study Bacteria?
Hare, Patricia J; Mok, Wendy W K Frontiers for Young Minds 2023 Jun
Stimulating Transcription in Antibiotic-Tolerant Escherichia coli Sensitizes It to Fluoroquinolone and Nonfluoroquinolone Topoisomerase Inhibitors.
Antimicrobial Agents and Chemotherapy 2023 Mar: e0163922
Resistance-resistant Antibacterial Treatment Strategies
Frontiers in Antibiotics 2023 Jan; doi: 10.3389/frabi.2023.1093156
Probiotic Escherichia coli Nissle 1917 Inhibits Bacterial Persisters that Survive Fluoroquinolone Treatment
Journal of Applied Microbiology 2022 Mar; doi: 10.1111/jam.15541.
Single-Cell Technologies to Study Phenotypic Heterogeneity and Bacterial Persisters
Microorganisms 2021 Nov;9(11):2277
The AcrAB-TolC Efflux Pump Impacts Persistence and Resistance Development in Stationary-Phase Escherichia coli Following Delafloxacin Treatment.
Byrd, Brandon A; Zenick, Blesing; Rocha-Granados, Maria C; Englander, Hanna E; Hare, Patricia J; LaGree, Travis; DeMarco, Angela M; Mok, Wendy W K Antimicrobial Agents and Chemotherapy 2021 Jun; 65: e0028121
Dodecylamine rapidly kills of spores of multiple Firmicute species: properties of the killed spores and the mechanism of the killing.
DeMarco, A M; Korza, G; Granados, M R; Mok, W W K; Setlow, P Journal of Applied Microbiology 2021 May; in press
Levels and Characteristics of mRNAs in Spores of Firmicute Species.
Byrd, Brandon; Camilleri, Emily; Korza, George; Craft, D Levi; Green, Joshua; Rocha Granados, Maria; Mok, Wendy W K; Caimano, Melissa J; Setlow, Peter Journal of Bacteriology 2021 May; 203: e0001721
The social network: Impact of host and microbial interactions on bacterial antibiotic tolerance and persistence.
Rocha-Granados; Maria C; Zenick, Blesing; Englander, Hanna E; Mok, Wendy W K Cellular Signalling 2020 Aug; 75:109750
Killing of bacterial spores by dodecylamine and its effects on spore inner membrane properties.
Mokashi, S; Kanaan, J; Craft, D L; Byrd, B; Zenick, B; Laue, M; Korza, G; Mok, W W K; Setlow, P Journal of Applied Microbiology 2020 Jun; 129(6):1511-1522
Lack of efficient killing of purified dormant spores of Bacillales and Clostridiales species by glycerol monolaurate in a non-aqueous gel.
Green, J; Korza, G; Granados, M R; Zenick, B; Schlievert, P M; Mok, W W K; Setlow, P Letters in Applied Microbiology 2020 Jun; 70(6): 407-412
DNA damage Kills Bacterial Spores and Cells Exposed to 222 nm UV Radiation.
Taylor, Willie; Camilleri, Emily; Craft, D Levi; Korza, George; Rocha Granados, Maria; Peterson, Jaliyah; Szczpaniak, Renata; Weller, Sandra K; Moeller, Ralf; Douki, Thierry; Mok, Wendy W K; Setlow., Peter Applied Environmental Microbiology 2020 Apr; 86(8): e03039-19
Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic.
Barrett, Theresa C; Mok, Wendy W K; Murawski, Allison M; Brynildsen, Mark P Nature Communications 2019 Mar;10(1):1177
Publications Pre-2019:
Timing of DNA damage responses impacts persistence to fluoroquinolones.
Mok, Wendy W K; Brynildsen, Mark P Proceedings of the National Academy of Sciences of the United States of America 2018 Jul;115(27):E6301-E6309
Biased inheritance protects older bacteria from harm.
Barrett, Theresa C; Mok, Wendy W K; Brynildsen, Mark P Science (New York, N.Y.) 2017 Apr;356(6335):247-248
An Orphan Riboswitch Unveils Guanidine Regulation in Bacteria.
Mok, Wendy W K; Brynildsen, Mark P Molecular Cell 2017 Jan;65(2):205-206
Non-Monotonic Survival of Staphylococcus aureus with Respect to Ciprofloxacin Concentration Arises from Prophage-Dependent Killing of Persisters.
Sandvik, Elizabeth L; Fazen, Christopher H; Henry, Theresa C; Mok, Wendy W K; Brynildsen, Mark P Pharmaceuticals (Basel, Switzerland) 2015 Nov;8(4):778-92
RNA Futile Cycling in Model Persisters Derived from MazF Accumulation.
Mok, Wendy W K; Park, Junyoung O; Rabinowitz, Joshua D; Brynildsen, Mark P mBio 2015 Nov;6(6):e01588-15
Impacts of global transcriptional regulators on persister metabolism.
Mok, Wendy W K; Orman, Mehmet A; Brynildsen, Mark P Antimicrobial Agents and Chemotherapy 2015 May;59(5):2713-9
Aminoglycoside-enabled elucidation of bacterial persister metabolism.
Orman, Mehmet A; Mok, Wendy W K; Brynildsen, Mark P Current Protocols in Microbiology 2015 Feb;3617.9.1-14
A highly efficient molecular cloning platform that utilises a small bacterial toxin gene.
Mok, Wendy W K; Li, Yingfu Chembiochem : a European Journal of Chemical Biology 2013 Apr;14(6):733-8
Developing fluorogenic RNA-cleaving DNAzymes for biosensing applications.
Ali, M Monsur; Aguirre, Sergio D; Mok, Wendy W K; Li, Yingfu Methods in Molecular Biology (Clifton, N.J.) 2012 Jan;848395-418
Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli.
Mok, Wendy W K; Patel, Nirav H; Li, Yingfu The Journal of Biological Chemistry 2010 Dec;285(53):41627-36
Characterization of an RNA-cleaving deoxyribozyme with optimal activity at pH 5.
Kandadai, Srinivas A; Mok, Wendy W K; Ali, Md Monsur; Li, Yingfu Biochemistry 2009 Aug;48(31):7383-91
Identification of a toxic peptide through bidirectional expression of small RNAs.
Mok, Wendy W K; Navani, Naveen K; Barker, Courtney; Sawchyn, Bobbijo L; Gu, Jimmy; Pathania, Ranjana; Zhu, Rebecca D; Brown, Eric D; Li, Yingfu Chembiochem : a European Journal of Chemical Biology 2009 Jan;10(2):238-41
In vitro selection of protein-binding DNA aptamers as ligands for biosensing applications.
Navani, Naveen K; Mok, Wing Ki; Yingfu, Li Methods in Molecular Biology (Clifton, N.J.) 2009 Jan;504399-415
Non-molecular-clock-like evolution following viral origins in homo sapiens.
Mok, Wendy; Seto, Kelly; Stone, Jon Evolutionary Bioinformatics Online 2007 Sep;3263-6