Members

Mayu Inaba PI

Mayu Inaba

Principal Investigator
Email: inaba@uchc.edu

Research interests; Asymmetric stem cell division. cell-cell interaction,  cell competition, gene redundancy.

Matthew Antel

Graduate Student

Email:antel@uchc.edu

I am screening candidate genes using RNAi in order to find genes involved in regulating asymmetric stem cell divisions in the male germline. I’m interested in investigating the localization of mRNAs for these genes during division, and elucidating the molecular mechanisms by which they may regulate divisions of germ stem cells.

Muhammed Burak Bener

Graduate Student
Email: bener@uchc.edu

1)  My research project is focused on asymmetric cell division in Drosophila female germline stem cells. When stem cells divide, they generate one stem cell and one differentiating daughter cell. I am investigating intracellular cell-fate determining factors play a role in this asymmetry. 2)  I am interested in microtubule behavior during germline stem cell divisions in Drosophila ovary.

Taylor Simao

Medical Student

Email: taylor.simao@uconn.edu

Mec17 is a gene encoding an enzyme believed to catalyze the acetylation of alpha-tubulin at lysine residue, K40. To investigate the function of this gene, I have generated a knock-out Drosophila line through utilization of CRISPR/Cas9 technology. I am now investigating how microtubule acetylation impacts Drosophila oogenesis.

I am also interested in developing a protocol for the cryopreservation of Drosophila embryos that utilizes pressure as a means to achieve higher hatch/eclosion rates and fertility post-thawing. The ability to cryopreserve Drosophila embryos of different strains successfully and efficiently would be an ideal way to reduce the financial/time costs, space requirements, and any undesired mutations/contamination associated with flipping stocks.

 

 

 

Alumni

Abigail Descoteaux
Research Assistant, January 2018-August 2018

Sophia Ladyzhets
Glastonbury High School
September 2017-August 2018

Stem Cells: Division in the Ovaries and Testes

Naiya Patel
Glastonbury High School
September 2018-August 2019