How do stem cells cause diseases?

Our primary focus is to explore how physiological stem cells and stem-like tumor cells behave using Drosophila testis. This small organism enables us to conduct long-term live imaging, allowing us to monitor cellular behavior in real tissues. Additionally, the genetic manipulability of Drosophila facilitates the rapid development of new genetic tools. Since numerous mechanisms are shared between fly and human stem cells, Drosophila has been contributing to study common regulations of many stem cell systems.

Our goal is to understand various stem cell-mediated conditions, including cancer, degenerative diseases, infertility, and age-related tissue dysfunctions.

Congratulations to Emma! Her striking image of a testis filled with scattered sperm has been chosen for the cover page. Well done!