Past Seminars

Date Speaker Home Institution Title Host
September 19, 2024 John Lis, Ph.D. Cornell University Dissecting the Molecular Architecture and Regulatory Mechanisms of a Robust Long-range Enhancer Michael Guertin
May 16, 2024 Hiten Madhani, M.D., Ph.D. University Of California, San Francisco Large-scale CRISPR base editing to understand the human spliceosome Brenton Graveley
May 2, 2024 Emma Farley, Ph.D. University of California San Diego Affinity optimizing enhancer variants disrupt development Michael Guertin
February 16, 2024 Thomas Maniatis, Ph.D. Columbia University Protocadherin Gene Cluster: A Generator of Cell Surface Barcodes Required for Normal Brain Wiring Brenton Graveley
February 2, 2024 Doris Kretzschmar, Ph.D. Oregon Health and Science University Connecting circadian disruptions and Alzheimers disease Blanka Rogina
January 8, 2024 Eric Lai, Ph.D. Sloan Kettering Institute microRNAs and RNAi: from mechanisms to biology Brenton Graveley
December 14, 2023 Marc Mendillo, Ph.D. Northwestern University Delineating Mechanisms of Cancer Cell Stress Resilience Michael Guertin
November 30, 2023 Ashleigh Schaffer, Ph.D. Case Western Reserve University Mechanisms of selective vulnerability in RNA binding protein-associated pediatric neurological disease Pedro Miura
April 27, 2023 Sam Sternberg, Ph.D. Columbia University Discovery and development of CRISPR-associated transposases Brenton Graveley
April 20, 2023 Eric Wagner, Ph.D. UConn Health Integrator is a Promoter-Proximal Termination Complex Critical for Transcriptional Control Brenton Graveley
March 30, 2023 Yingqun Huang, M.D., Ph.D. Yale University Overcoming a TET offensive in multiple diseases Brenton Graveley
March 16, 2023 Frederick S. Varn, Ph.D. The Jackson Laboratory Dissecting tumor-microenvironment interactions and their role in the evolution of diffuse glioma Brenton Graveley
March 2, 2023 Leighton Core, Ph.D. UConn Mapping transcriptomes and defining points of gene regulation with nascent RNA sequencing Brenton Graveley
February 23, 2023 Oscar Vargas-Rodriguez, Ph.D. UConn Health Nonocanonical translation of the genetic code by a new tRNA family Brenton Graveley
 January 12, 2023
Sarah Aitken, Ph.D.
 University of Cambridge
Disentangling strand interactions in DNA damage and repair Brenton Graveley
December 1, 2022 Summer Thyme, Ph.D. The University of Alabama at Birmingham Using Zebrafish to Study Neurodevelopmental Disorders and Discover Treatments Brenton Graveley
November 17, 2022 Lindy Barrett, Ph.D. Broad Institute Leveraging iPSC Models to Study Neural Development and Disease
November 3, 2022 Mira Moufarrej, Ph.D. The Column Group Improving prenatal care through liquid biopsies Stefan Pinter
October 20, 2022 Ronald Breaker, Ph.D. Yale University Modern Riboswitches Reveal Ancient RNA Capabilities and Limitations Sandra Garrett
October 6, 2022
Michael Guertin, Ph.D. University of Connecticut School of Medicine Kinetic networks identify key regulatory nodes and transcription factor functions in early adipogenesis Pedro Miura
October 4, 2022
Bernhard Payer, Ph.D. Centre for Genomic Regulation (CRG), Barcelona, Spain Epigenetic reprogramming of the X chromosome in the female mammalian germ line Stefan Pinter
September 30, 2022
Melissa Moore, Ph.D. (Herbert and Esther Brandwein Lecture) Chief Scientific Officer, Scientific Affairs, Moderna, Inc., and Co-Founder, Via Scientific mRNA as Medicine
Brenton Graveley
September 8, 2022 Eric Wang The Jackson Laboratory Overcoming therapy resistance in hematologic malignancies Brenton Graveley
March 24, 2022 Lori Passmore MRC Laboratory and Moleculare Biology, Cambridge, UK Molecular Insights into the mRNA3′ – end processing machinery Brenton Graveley
March 18, 2021 Jay Shendure University of Washington – Genome Sciences Global views of Mammalian Development Brenton Graveley
March 4, 2021 Vincent Pasque KU Leuven, Belgium Genome and epigenome regulatory principles in early mammalian  development, stem cells and reprogramming Stefan Pinter
February 18, 2021 Thorold Theunissen Washington University, St. Louis Understanding human pluripotent stem cell states and their applications Stefan Pinter
January 21, 2021 Gosia Trynka Welcome Genome Campus
Hinxton, Cambridge, UK
Interpreting GWAS variants with chromatin marks and single cell transcriptomics Justin Cotney
December 17, 2020 Elizabeth J. Leslie Emory University School of Medicine From GWAS to Genomes: New Insights into the Human Genetics of Orofacial Clefts Justin Cotney
December 3, 2020 Aaron Quinlan University of Utah Patterns and consequences of mutation in the human germline Justin Cotney
November 19, 2020 Erica Hutchkins Caltech Unraveling the mechanisms of the neural crest epithelial – mesenchymal transition Stefan Pinter
November 5, 2020 Mingxia Gu Cincinnati Children’s Hospital Medical Center Endocardial contribution to heart development and disease Stefan Pinter
October 22, 2020 Youngmok Lee Asst Professor, Department of Pediatrics, UCHC

Requesting joint appointment in department

Gene therapy for Glycogen Storage Disease Type I Brent Graveley
Isolde Bates
October 8, 2020 Miguel Moreno-Mateos Andalusian Center for Developmental Biology Understanding early vertebrate development: A CRISPR-Cas view Jean-Denis Beaudoin
February 25, 2020 Dr. Dionna Kasper Yale University School of Medicine
Yale Cardiovascular Research Center &  Department of Genetics
Special Seminar: “How to make a stem cell: Gene regulatory principles learned from vascular fate transitions” Dr. Brenton Graveley
February 3, 2020 Dr. Max Staller Edison Family Center for Genome Sciences and Systems Biology
Washington University School of Medicine, St. Louis
Special Seminar: “Probing the sequence-to-function relationship of transcription factor activation domains” Dr. Brenton Graveley
January 16, 2020 Dr. Tania Rozario Morgridge Institute for Research
University of Wisconsin-Madison
Special Seminar: “Making heads or tails of tapeworms: Region-specific regulation of stem cell-driven regeneration in Hymenolepisdiminuta” Dr. Brenton Graveley
January 13, 2020 Dr. Margarida Cardoso Moreira University of Heidelberg, Germany Special Seminar: “Origins and evolution of organs” Dr. Brenton Graveley
January 10, 2020 Dr. Bushra Raj Harvard University Special Seminar: “Global insights into brain diversity, development and lineage at single-cell resolution” Dr. Brenton Graveley
January 7, 2020 Dr. Nicholas Tran Harvard University Special Seminar: “Applying a retinal cell atlas to examine mechanisms of selective neuron resilience and axon regeneration” Dr. Brenton Graveley
September 26, 2019 Dr. Jaime Imitola UConn Health “Human Cellular Models to advance mechanisms and treatments for neurological diseases” Dr. Brenton Graveley
September 26, 2019 Dr. Jaime Imitola UConn Health “Human Cellular Models to advance mechanisms and treatments for neurological diseases” Dr. Brenton Graveley
July 9, 2019 Dr. Ling-Ling Chen Chinese Academy of Sciences “Linking RNA processing and function” Dr. Gordon Carmichael
July 9, 2019 Dr. Ling-Ling Chen Chinese Academy of Sciences “Linking RNA processing and function” Dr. Gordon Carmichael
April 4, 2019 Dr. William Fairbrother Brown University “Pathogenic variations often disrupt splicing – implications for clinical genetics and evolutionary models of regulatory signals” Dr. Brenton Graveley
January 17, 2019 Dr. Rebekah Rogers UNC Charlotte “When Bad Things Happen to Good Genomes: genetic tragedies in mammoths and poison dart frogs” Dr. Charles Lee, JAX GM and
Dr. Brenton Graveley
January 17, 2019 Dr. Rebekah Rogers UNC Charlotte “When Bad Things Happen to Good Genomes: genetic tragedies in mammoths and poison dart frogs” Dr. Charles Lee, JAX GM and
Dr. Brenton Graveley
December 13, 2018 Dr. Mayu Inaba UConn Health “Stem cell receptor degradation by niche cells restricts signaling” Dr. Blanka Rogina
November 29, 2018 Dr. Duygu Ucar The Jackson Laboratory for Genomic Medicine “Sex dimorphism in human immune system aging” Dr. Blanka Rogina
October 26, 2018 Dr. Eric Van Nostrand University of California San Diego Special Seminar: “Exploring RNA biology at scale” Dr. Brenton Graveley
October 4, 2018 Dr. Scott Bultman University of North Carolina “The role of microbiome-derived metabolism in cancer prevention and therapy” GDB Graduate Students
July 11, 2018 Dr. Adrian Krainer Cold Spring Harbor Laboratory Herbert and Esther Bennett Brandwein Lecture: “Spinraza: The First Approved Therapy for Spinal Muscular Atrophy” Dr. Brenton Graveley
May 24, 2018 6th UConn Fly Club UConn Multiple Talks Dr. Blanka Rogina
May 10, 2018 Dr. Stephen Helfand Brown University “Retrotransposons as agents of somatic diversity, disease and aging” Dr. Blanka Rogina
March 29, 2018 Dr. Aoife Heaslip UConn “Oh the places you’ll go! Vesicle transport in Toxoplasma gondii” Dr. Arthur Gunzl
March 15, 2018 Dr. Beiyan Zhou UConn Health “Macrophage Polarization and Obesity” Dr. Blanka Rogina
March 1, 2018 Dr. Christine Beck UConn Health and The Jackson Laboratory for Genomic Medicine “Repetitive sequences and genomic plasticity” Dr. Blanka Rogina
February 20, 2018 Dr. Li Yang Chinese Academy of Science “Genome-wide characterization of circular RNAs” Dr. Gordon Carmichael
December 14, 2017 Dr. David Zappulla Johns Hopkins University “Telomerase: RNP architecture, telomere maintenance, and senescence without it” Dr. Brenton Graveley
December 7, 2017 Dr. Patrick Murphy UConn Health “Alternative splicing as a novel axis in endothelial-immune interactions” Dr. Stormy Chamberlain
November 9, 2017 Multiple Speakers Multiple Institutions Northeastern Glenn Symposium on the Biology of Aging Dr. Blanka Rogina
October 19, 2017 Dr. Zeeshan Ahmed UConn Health “Dealing practical issues associated to the clinical and high throughput genomic data integration for precision medicine” Dr. Brenton Graveley
June 1, 2017 Dr. Nitika Badjatia – Henderson Prize Awardee Penn State “Biochemical Reconstitution of Nucleosome Organization at Gene Promoters Dr. Arthur Gunzl and
Dr. Blanka Rogina
March 9, 2017 Dr. Camron Bryant Boston University “Systems genetic analysis of drug and food addiction traits in mice” Dr. Erin Young
September 12, 2016 Dr. Christian P. Schaaf Baylor College of Medicine “Translational approaches to rare neurodevelopmental disorders” **This seminar is held at the JAX-GM Auditorium**
June 30, 2016 Dr. Albert Shaw Yale University “Effects of Aging on Signatures of Influenza Vaccine Response”
May 5, 2016 Dr. Pierre-Antoine Defossez University Paris Diderot “A hypercompetitive histone mimic in DNA Ligase 1 links DNA replication and UHRF1 recruitment: implications for DNA remethylation”
March 24, 2016 Dr. Shangqin Guo Yale University “Visualizing the birth of induced pluripotent stem cells: Seeing the non-stochastic events”
January 14, 2016 Dr. Albert Cheng The Jackson Laboratory for Genomic Medicine “Upgrading CRISPR/Cas”
September 10, 2015 Dr. Edison Liu The Jackson Laboratory for Genomic Medicine “Genomic Configuration and Systems Biology for Breast Cancer”