Dr. Scanlon currently works on understanding extrinsic mechanisms that underlie hematopoietic progenitor cell fate decisions. She has developed a novel method for time-lapse microscopy of bipotent progenitors dividing and committing to two potential lineages. She is also interested in developing 3D engineered in vitro cell culture models to further investigate spatial regulation between cells of the bone marrow microenvironment.
Mixed Mk/E Colony Grown from Single Human MEP: The entire colony arose from a single human bipotent Megakaryocytic-Erythroid Progenitor (MEP). Megakaryocyte-committed cells are expressing CD41 (green fluorescence) and CD235a (red fluorescence).