Welcome to the Scanlon Lab
The recently established Scanlon Lab in the Center for Regenerative Medicine and Skeletal Development aims to understand the molecular crosstalk between disparate cell types in the bone marrow microenvironment that influences lineage commitment of hematopoietic progenitors. Specifically, we utilize the human megakaryocytic-erythroid progenitor (MEP) as a model of hematopoietic progenitors and explore both intrinsic (genetic and signaling cascades) and extrinsic factors (systemic factors or cues from neighboring cell types) that regulate its bipotency, expansion and fate specification to the megakaryocytic or erythroid lineage.
About Dr. Scanlon
Dr. Vanessa Scanlon is a wife and mom to two boys. She is passionate about science and strengthening the pipeline of underrepresented individuals to successful research careers. Currently, Dr. Scanlon works on understanding extrinsic mechanisms that underly hematopoietic progenitor cell fate decisions. She has developed a novel method for time-lapse microscopy of bipotent progenitors dividing and committing to two potential lineages. She is also interested in developing 3D engineered in vitro cell culture models to further investigate spatial regulation between cells of the bone marrow microenvironment.