Current preprints
19. Ahern DT, Bansal P, Faustino IV, Glatt-Deeley HR, Massey RE, Kondaveeti Y, Banda EC, Pinter SF. Isogenic hiPSC models of Turner syndrome reveal shared roles of inactive X and Y in the human cranial neural crest network. bioRxiv preprint 2023.03.08.531747v2 https://www.biorxiv.org/content/10.1101/2023.03.08.531747v2
Publications
18. Bansal P, Banda EC, Glatt-Deeley HR, Stoddard CE, Linsley JW, Arora N, Deleschaux C, Ahern DT, Kondaveeti Y, Massey RE, Nicouleau M, Wang S, Sabariego-Navarro M, Dierssen M, Finkbeiner S, Pinter SF. A dynamic in vitro model of Down syndrome neurogenesis with trisomy 21 gene dosage correction. Science Advances 2024 Jun 7;10(23):eadj0385. https://doi.org/10.1126/sciadv.adj0385
17. Ahern DT, Bansal P, Armillei MK, Faustino IV, Kondaveeti Y, Glatt-Deeley HR, Banda EC, Pinter SF. Monosomy X in isogenic human iPSC-derived trophoblast model impacts expression modules preserved in human placenta. Proceedings of the National Academy of Sciences USA. 2022 Oct 4;119(40):e2211073119. https://doi.org/10.1073/pnas.2211073119
16. Bansal P, Ahern DT, Kondaveeti Y, Qiu CW, Pinter SF. Contiguous erosion of the inactive X in human pluripotency concludes with global DNA hypomethylation. Cell Reports. 2021 Jun 8;35(10):109215. https://doi.org/10.1016/j.celrep.2021.109215
15. Bauer M, Vidal E, Zorita E, Üresin N, Pinter SF, Filion GJ, Payer B. Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation. Nat Communications. 2021 Jun 9;12(1):3499. https://doi.org/10.1038/s41467-021-23610-1
14. Bansal, P., Kondaveeti, Y., & Pinter, S. F. (2020). Forged by DXZ4, FIRRE, and ICCE: How Tandem Repeats Shape the Active and Inactive X Chromosome. Frontiers in Cell and Developmental Biology, 7. https://doi.org/10.3389/fcell.2019.00328
13. Froberg, J. E., Pinter, S. F., Kriz, A. J., Jégu, T., & Lee, J. T. (2018). Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape. Nature Communications, 9(1), 5004. https://doi.org/10.1038/s41467-018-07446-w
12. Chu, H.-P., Froberg, J. E., Kesner, B., Oh, H. J., Ji, F., Sadreyev, R., … Lee, J. T. (2017). PAR-TERRA directs homologous sex chromosome pairing. Nature Structural and Molecular Biology, 24(8). https://doi.org/10.1038/nsmb.3432
11. Savol, A. J., Wang, P. I., Jeon, Y., Colognori, D., Yildirim, E., Pinter, S. F., … Sadreyev, R. I. (2017). Genome-wide identification of autosomal genes with allelic imbalance of chromatin state. PLoS ONE, 12(8). https://doi.org/10.1371/journal.pone.0182568
10. Pinter, S. F. (2016). A Tale of Two Cities: How Xist and its partners localize to and silence the bicompartmental X. Seminars in Cell & Developmental Biology, 56, 19–34. https://doi.org/10.1016/j.semcdb.2016.03.023
9. Pinter, S. F., Colognori, D., Beliveau, B. J., Sadreyev, R. I., Payer, B., Yildirim, E., … Lee, J. T. (2015). Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome. Genetics, 200(2), 537–549. https://doi.org/10.1534/genetics.115.176263
8. Kung, J. T., Kesner, B., An, J. Y., Ahn, J. Y., Cifuentes-rojas, C., Colognori, D., … Lee, J. T. (2015). Locus-Specific Targeting to the X Chromosome Revealed by the RNA Interactome of CTCF. Molecular Cell, 57(2), 361–375. https://doi.org/10.1016/j.molcel.2014.12.006
7. Simon, M. D., Pinter, S. F., Fang, R., Sarma, K., Rutenberg-Schoenberg, M., Bowman, S. K., … Lee, J. T. (2013). High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation. Nature, 504(7480), 465–469. https://doi.org/10.1038/nature12719
6. Sadreyev, R. I., Yildirim, E., Pinter, S. F., & Lee, J. T. (2013). Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci. Proceedings of the National Academy of Sciences USA, 110(17), 6949–6954. https://doi.org/10.1073/pnas.1216449110
5. Pinter, S. F., Sadreyev, R. I., Yildirim, E., Jeon, Y., Ohsumi, T. K., Borowsky, M., & Lee, J. T. (2012). Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations. Genome Research, 22(10), 1864–1876. https://doi.org/10.1101/gr.133751.111
4. Yildirim, E., Sadreyev, R. I., Pinter, S. F., & Lee, J. T. (2012). X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription. Nature Structural & Molecular Biology, 19(1), 56–61. https://doi.org/10.1038/nsmb.2195
3. Spencer, R. J., del Rosario, B. C., Pinter, S. F., Lessing, D., Sadreyev, R. I., & Lee, J. T. (2011). A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation. Genetics, 189(2), 441–454. https://doi.org/10.1534/genetics.111.132662
2. Donohoe, M. E., Silva, S. S., Pinter, S. F., Xu, N., & Lee, J. T. (2009). The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature, 460(7251), 128–132. https://doi.org/10.1038/nature08098
1. Pinter, S. F., Aubert, S. D., & Zakian, V. (2008). The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA. Molecular and Cellular Biology, 28(21), 6594–6608. https://doi.org/10.1128/MCB.00191-08