Project 8p September 2023 Research Newsletter

Dr. Pinter’s lab is currently working on a project to equip 8p and euploid iPS cells with inducible NGN2, to drive neuronal differentiation, and inducible CRISPR constructs capable of turning gene expression on (CRISPRa) or off (CRISPRi) in a targeted fashion. These tools will be used to dissect the impact of changes in gene dosage of individual 8p genes.