| Syndrome | Clinical Manifestations | Gene |
| Hereditary Breast-Ovarian Cancer Syndrome | Breast cancer Ovarian cancer Pancreatic cancer Prostate cancer |
BRCA1 BRCA2 |
| Hereditary Non-Polyposis Colon Cancer (HNPCC) Also Known as Lynch Syndrome | Colon cancer Endometrial cancer Stomach cancer Ovarian cancer Prostate cancer Other forms of cancer |
MLH1 MLH2 MSH6 PMS2 |
| Familial Adenomatous Polyposis (FAP)/Attenuated FAP | Numerous adenomatous colonic polyps Colon cancer Desmoid tumors |
APC |
| Hereditary Melanoma | Melanoma Pancreatic cancer |
CDKN2A |
| Multiple Endocrine Neoplasia (MEN) 2a and 2b; Familial Medullary Thyroid Cancer | Medullary thyroid cancer Parathyroid hyperplasia Pheochromocytoma |
RET |