Publications in actin-based cell motility, cytokinesis, and transmembrane signaling:
Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Chavali SS, Chou SZ, Cao W, Pollard TD, De La Cruz EM, Sindelar CV. Nat Commun. 2024 Mar 6;15(1):2059. doi: 10.1038/s41467-024-46179-x.
Mechanism of actin filament branch formation by Arp2/3 complex revealed by a high resolution cryo-EM structure of the branch junction.
Chou SZ, Chatterjee M, Pollard TD. Proc Natl Acad Sci U S A. 2022 Dec 6 0;119(49):0000-0000. doi: 10.1073/pnas.2206722119. Epub 2022 Nov 29.
Cryo-electron microscopy structures of pyrene-labeled ADP-Pi- and ADP-actin filaments.
Chou SZ, Pollard TD. Nat Commun. 2020 Nov 19;11(1):5897. doi: 10.1038/s41467-020-19762-1.
Structural basis for polarized elongation of actin filaments.
Zsolnay V, Katkar HH, Chou SZ, Pollard TD, Voth GA. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30458-30464. doi: 10.1073/pnas.2011128117. Epub 2020 Nov 16.
Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides.
Chou SZ, Pollard TD. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4265-4274. doi: 10.1073/pnas.1807028115. Epub 2019 Feb 13.
Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments.
Espinoza-Sanchez S, Metskas LA, Chou SZ, Rhoades E, Pollard TD. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8642-E8651. doi: 10.1073/pnas.1717594115. Epub 2018 Aug 27.
Ligand-induced architecture of the leptin receptor signaling complex.
Mancour LV, Daghestani HN, Dutta S, Westfield GH, Schilling J, Oleskie AN, Herbstman JF, Chou SZ, Skiniotis G. Mol Cell. 2012 Nov 30;48(4):655-61. doi: 10.1016/j.molcel.2012.09.003. Epub 2012 Oct 11.