{"id":800,"date":"2017-03-27T12:55:02","date_gmt":"2017-03-27T16:55:02","guid":{"rendered":"https:\/\/health.uconn.edu\/synapse\/?page_id=800"},"modified":"2024-08-16T18:05:17","modified_gmt":"2024-08-16T22:05:17","slug":"metaslider-image-1-2-2","status":"publish","type":"page","link":"https:\/\/health.uconn.edu\/synapse\/metaslider-image-1-2-2\/","title":{"rendered":"C1QL1 promotes remyelination"},"content":{"rendered":"<div id=\"pl-800\"  class=\"panel-layout\" ><div id=\"pg-800-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-800-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-800-0-0-0\" class=\"so-panel widget widget_widget_sp_image widget_sp_image panel-first-child panel-last-child\" data-index=\"0\" ><h3 class=\"widget-title\"> <\/h3><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"640\" alt=\" \" class=\"attachment-full\" style=\"max-width: 100%;\" src=\"https:\/\/health.uconn.edu\/synapse\/wp-content\/uploads\/sites\/110\/2024\/08\/Figure-8-e1723845684831.png\" \/><\/div><\/div><div id=\"pgc-800-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-800-0-1-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"textwidget\"><p><span>The drug cuprizone when fed to mice causes demyelination and a death of oligodendrocytes (marked by co-expression of CC1 and ASPA). When returned to a normal diet, spontaneous recovery occurs. We found that mice lacking the\u00a0<\/span><i>C1ql1<\/i><span>\u00a0gene do not recover as well, suggesting that the C1QL1 protein is beneficial for recovery from demyelination.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The drug cuprizone when fed to mice causes demyelination and a death of oligodendrocytes (marked by co-expression of CC1 and ASPA). When returned to a normal diet, spontaneous recovery occurs. We found that mice lacking the\u00a0C1ql1\u00a0gene do not recover as well, suggesting that the C1QL1 protein is beneficial for recovery from demyelination.<\/p>\n","protected":false},"author":97,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-25 23:59:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/pages\/800"}],"collection":[{"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/users\/97"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/comments?post=800"}],"version-history":[{"count":4,"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/pages\/800\/revisions"}],"predecessor-version":[{"id":810,"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/pages\/800\/revisions\/810"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/synapse\/wp-json\/wp\/v2\/media?parent=800"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}