{"id":50,"date":"2017-05-16T14:42:41","date_gmt":"2017-05-16T18:42:41","guid":{"rendered":"https:\/\/health.uconn.edu\/spirochete-lab\/?page_id=50"},"modified":"2025-09-16T14:18:28","modified_gmt":"2025-09-16T18:18:28","slug":"publications","status":"publish","type":"page","link":"https:\/\/health.uconn.edu\/spirochete-lab\/syphilis-research\/publications\/","title":{"rendered":"Syphilis Publications"},"content":{"rendered":"<div class=\"in-page-tabs\"><ul id=\"menu-syphilis-research\" class=\"menu nav nav-tabs\"><li id=\"menu-item-126\" class=\"menu-item menu-item-type-post_type menu-item-object-page\"><a href=\"https:\/\/health.uconn.edu\/spirochete-lab\/syphilis-research\/syphilis-research\/\">Syphilis Research<\/a><\/li><li id=\"menu-item-123\" class=\"menu-item menu-item-type-post_type menu-item-object-page\"><a href=\"https:\/\/health.uconn.edu\/spirochete-lab\/syphilis-research\/syphilis-team\/\">Syphilis Research Team<\/a><\/li><li id=\"menu-item-124\" class=\"menu-item menu-item-type-post_type menu-item-object-page\"><a href=\"https:\/\/health.uconn.edu\/spirochete-lab\/syphilis-research\/syphilis-collaborations\/\">Syphilis Collaborations<\/a><\/li><li id=\"menu-item-125\" class=\"menu-item menu-item-type-post_type menu-item-object-page\"><a href=\"https:\/\/health.uconn.edu\/spirochete-lab\/syphilis-research\/publications\/\">Syphilis Publications<\/a><\/li><\/ul><\/div><div id=\"pl-50\"  class=\"panel-layout\" ><div id=\"pg-50-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-50-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-50-0-0-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"textwidget\"><h5>Syphilis Research<\/h5>\n<h1>Publications<\/h1>\n<\/div><\/div><\/div><\/div><div id=\"pg-50-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-50-1-0\"  class=\"panel-grid-cell\" ><div id=\"panel-50-1-0-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"textwidget\"><h2>Selected Syphilis Publications<\/h2>\n<p>&nbsp;<\/p>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"section\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<div class=\"highwire-cite-authors\">\n<div class=\"inline-authors\">\n<div class=\"authors\">\n<div class=\"authors-list\">\n<p data-start=\"321\" data-end=\"862\"><strong data-start=\"321\" data-end=\"571\">Posp\u00ed\u0161ilov\u00e1 P, Fedrov\u00e1 P, Vrbov\u00e1 E, Hennelly CM, Aghakhanian F, Hawley KL, Bettin EB, Davenport TC, Bruisten SM, Zondag HCA, Grange PA, Dupin N, Arora N, Noda AA, Se\u00f1a AC, Caimano MJ, Salazar JC, Juliano JJ, Moody MA, Radolf JD, Parr JB, \u0160majs D.<\/strong><br data-start=\"571\" data-end=\"574\" \/>Analysis of <em data-start=\"586\" data-end=\"606\">Treponema pallidum<\/em> subsp. <em data-start=\"614\" data-end=\"624\">pallidum<\/em> predicted outer membrane proteins (OMPeomes) in 21 clinical samples: variant sequences are predominantly surface-exposed. <em data-start=\"747\" data-end=\"757\">mSphere.<\/em> 2025 Aug 29:e0021325. doi:10.1128\/msphere.00213-25. PMID:40879370. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40879370\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40879370\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"864\" data-end=\"1457\"><strong data-start=\"864\" data-end=\"1186\">Bettin EB, Aghakhanian F, Hennelly CM, Chen W, Davenport TC, Hackl ST, Grassmann AA, Vargas-Cely F, Silva S, Garc\u00eda-Luna JA, Ramirez LG, Jiang Y, Yang L, Zheng H, Yang B, Posp\u00ed\u0161ilov\u00e1 P, \u0160majs D, Matoga MM, Hoffman IF, L\u00f3pez-Medina E, Nieselt K, Moody MA, Se\u00f1a AC, Salazar JC, Parr JB, Caimano MJ, Hawley KL, Radolf JD.<\/strong><br data-start=\"1186\" data-end=\"1189\" \/>Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of <em data-start=\"1290\" data-end=\"1310\">Treponema pallidum<\/em> outer membrane proteins. <em data-start=\"1336\" data-end=\"1350\">J Bacteriol.<\/em> 2025 Aug 21;207(8):e0015925. doi:10.1128\/jb.00159-25. PMID:40802283. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40802283\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40802283\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"1459\" data-end=\"1851\"><strong data-start=\"1459\" data-end=\"1565\">Delgado KN, Caimano MJ, Orbe IC, Vicente CF, La Vake CJ, Grassmann AA, Moody MA, Radolf JD, Hawley KL.<\/strong><br data-start=\"1565\" data-end=\"1568\" \/>Immunodominant extracellular loops of <em data-start=\"1606\" data-end=\"1626\">Treponema pallidum<\/em> FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities. <em data-start=\"1721\" data-end=\"1735\">PLoS Pathog.<\/em> 2024 Dec 23;20(12):e1012443. doi:10.1371\/journal.ppat.1012443. PMID:39715273. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39715273\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39715273\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"1853\" data-end=\"2285\"><strong data-start=\"1853\" data-end=\"1963\">Delgado KN, Vicente CF, Hennelly CM, Aghakhanian F, Parr JB, Claffey KP, Radolf JD, Hawley KL, Caimano MJ.<\/strong><br data-start=\"1963\" data-end=\"1966\" \/>Development and utilization of <em data-start=\"1997\" data-end=\"2017\">Treponema pallidum<\/em> expressing green fluorescent protein to study spirochete\u2013host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research. <em data-start=\"2171\" data-end=\"2178\">mBio.<\/em> 2025 Jan 8;16(1):e0325324. doi:10.1128\/mbio.03253-24. PMID:39611839. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39611839\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39611839\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"2287\" data-end=\"2873\"><strong data-start=\"2287\" data-end=\"2590\">Se\u00f1a AC, Matoga MM, Yang L, L\u00f3pez-Medina E, Aghakhanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jere E, Jiang Y, Juliano JJ, Posp\u00ed\u0161ilov\u00e1 P, Ramirez L, \u0160majs D, Tucker JD, Vargas Cely F, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB.<\/strong><br data-start=\"2590\" data-end=\"2593\" \/>Clinical and genomic diversity of <em data-start=\"2627\" data-end=\"2647\">Treponema pallidum<\/em> subspecies <em data-start=\"2659\" data-end=\"2669\">pallidum<\/em> to inform vaccine research: an international, molecular epidemiology study. <em data-start=\"2746\" data-end=\"2763\">Lancet Microbe.<\/em> 2024 Sep;5(9):100871. doi:10.1016\/S2666-5247(24)00087-9. PMID:39181152. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39181152\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39181152\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"2875\" data-end=\"3274\"><strong data-start=\"2875\" data-end=\"2981\">Delgado KN, Caimano MJ, Orbe IC, Vicente CF, La Vake CJ, Grassmann AA, Moody MA, Radolf JD, Hawley KL.<\/strong><br data-start=\"2981\" data-end=\"2984\" \/>Immunodominant extracellular loops of <em data-start=\"3022\" data-end=\"3042\">Treponema pallidum<\/em> FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities. <em data-start=\"3137\" data-end=\"3147\">bioRxiv.<\/em> 2024 Jul 30:2024.07.30.605823. doi:10.1101\/2024.07.30.605823. [Preprint]. PMID:39131275. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39131275\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39131275\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"3276\" data-end=\"3662\"><strong data-start=\"3276\" data-end=\"3365\">Vargas-Cely F, Silva S, Garc\u00eda-Luna JA, Ramirez LG, \u2026 Salazar JC, Radolf JD, Parr JB.<\/strong><br data-start=\"3365\" data-end=\"3368\" \/><em data-start=\"3368\" data-end=\"3388\">Treponema pallidum<\/em> genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia. <em data-start=\"3536\" data-end=\"3547\">PLoS One.<\/em> 2024 Jul 19;19(7):e0307600. doi:10.1371\/journal.pone.0307600. PMID:39028747. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39028747\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39028747\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"3664\" data-end=\"4005\"><strong data-start=\"3664\" data-end=\"3714\">Hennelly CM, Chen W, Aghakhanian F, \u2026 Parr JB.<\/strong><br data-start=\"3714\" data-end=\"3717\" \/>Clinical presentation of early syphilis and genomic sequences of <em data-start=\"3782\" data-end=\"3802\">Treponema pallidum<\/em> strains in patient specimens and isolates obtained by rabbit inoculation. <em data-start=\"3877\" data-end=\"3892\">J Infect Dis.<\/em> 2024 Dec 16;230(6):e1322-e1333. doi:10.1093\/infdis\/jiae322. PMID:38884588. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38884588\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38884588\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"4302\" data-end=\"4677\"><strong data-start=\"4302\" data-end=\"4341\">Chen W, Yang L, Zheng H, \u2026 Parr JB.<\/strong><br data-start=\"4341\" data-end=\"4344\" \/>Early syphilis in Guangzhou, China: presentation, molecular detection of <em data-start=\"4417\" data-end=\"4437\">Treponema pallidum<\/em>, and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing. <em data-start=\"4536\" data-end=\"4546\">medRxiv.<\/em> 2023 Oct 19:2023.10.17.23297169. doi:10.1101\/2023.10.17.23297169. [Preprint]. PMID:37905017. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37905017\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37905017\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"4679\" data-end=\"5045\"><strong data-start=\"4679\" data-end=\"4727\">Delgado KN, Rubin AF, Moody MA, \u2026 Hawley KL.<\/strong><br data-start=\"4727\" data-end=\"4730\" \/>Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of <em data-start=\"4882\" data-end=\"4902\">Treponema pallidum<\/em> BamA (TP0326). <em data-start=\"4918\" data-end=\"4934\">Front Immunol.<\/em> 2023 Aug 22;14:1222267. doi:10.3389\/fimmu.2023.1222267. PMID:37675118. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37675118\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37675118\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"5047\" data-end=\"5400\"><strong data-start=\"5047\" data-end=\"5105\">Hawley KL, Montezuma-Rusca JM, Delgado KN, \u2026 Luthra A.<\/strong><br data-start=\"5105\" data-end=\"5108\" \/>Extracellular loops of the <em data-start=\"5135\" data-end=\"5155\">Treponema pallidum<\/em> FadL orthologs TP0856 and TP0858 elicit IgG antibodies and IgG+-specific B cells in the rabbit model of experimental syphilis. <em data-start=\"5283\" data-end=\"5290\">mBio.<\/em> 2022 Aug 30;13(4):e0163922. doi:10.1128\/mbio.01639-22. PMID:35862766. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35862766\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35862766\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"5402\" data-end=\"5762\"><strong data-start=\"5402\" data-end=\"5460\">Hawley KL, Montezuma-Rusca JM, Delgado KN, \u2026 Luthra A.<\/strong><br data-start=\"5460\" data-end=\"5463\" \/>Structural modeling of the <em data-start=\"5490\" data-end=\"5510\">Treponema pallidum<\/em> outer membrane protein repertoire: a road map for deconvolution of syphilis pathogenesis and development of a syphilis vaccine. <em data-start=\"5639\" data-end=\"5653\">J Bacteriol.<\/em> 2021 Jul 8;203(15):e0008221. doi:10.1128\/JB.00082-21. PMID:33972353. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33972353\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33972353\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<p data-start=\"5764\" data-end=\"6233\"><strong data-start=\"5764\" data-end=\"5891\">Luthra A, Montezuma-Rusca JM, La Vake CJ, LeDoyt M, Delgado KN, Davenport TC, Fiel-Gan M, Caimano MJ, Radolf JD, Hawley KL.<\/strong><br data-start=\"5891\" data-end=\"5894\" \/>Evidence that immunization with TP0751, a bipartite <em data-start=\"5946\" data-end=\"5966\">Treponema pallidum<\/em> lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis. <em data-start=\"6102\" data-end=\"6116\">PLoS Pathog.<\/em> 2020 Sep 16;16(9):e1008871. doi:10.1371\/journal.ppat.1008871. PMID:32936831. <span class=\"\" data-state=\"closed\"><span class=\"ms-1 inline-flex max-w-full items-center relative top-[-0.094rem] animate-[show_150ms_ease-in]\" data-testid=\"webpage-citation-pill\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32936831\/\" target=\"_blank\" rel=\"noopener\" alt=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32936831\/\" class=\"flex h-4.5 overflow-hidden rounded-xl px-2 text-[9px] font-medium text-token-text-secondary! bg-[#F4F4F4]! dark:bg-[#303030]! transition-colors duration-150 ease-in-out\"><span class=\"relative start-0 bottom-0 flex h-full w-full items-center\"><span class=\"flex h-4 w-full items-center justify-between overflow-hidden\"><span class=\"max-w-full grow truncate overflow-hidden text-center\">PubMed<\/span><\/span><\/span><\/a><\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Syphilis Research Publications Selected Syphilis Publications &nbsp; Posp\u00ed\u0161ilov\u00e1 P, Fedrov\u00e1 P, Vrbov\u00e1 E, Hennelly CM, Aghakhanian F, Hawley KL, Bettin EB, Davenport TC, Bruisten SM, Zondag HCA, Grange PA, Dupin N, Arora N, Noda AA, Se\u00f1a AC, Caimano MJ, Salazar JC, Juliano JJ, Moody MA, Radolf JD, Parr JB, \u0160majs D.Analysis of Treponema pallidum subsp. [&hellip;]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":25,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-04-30 10:26:40","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/pages\/50"}],"collection":[{"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/users\/38"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/comments?post=50"}],"version-history":[{"count":95,"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/pages\/50\/revisions"}],"predecessor-version":[{"id":594,"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/pages\/50\/revisions\/594"}],"up":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/pages\/25"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/spirochete-lab\/wp-json\/wp\/v2\/media?parent=50"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}