\n\t\tFor Trainees and Students\n\t<\/h3>\n\t
Our research program is an integral part of our departmental activities and informs the treatment that we provide to our patients. We are also pleased that we involve medical and dental students, trainees (interns, residents, and clinical and research fellows), and other students (high school, undergraduates, and graduate students) in our research activities that are consistent with the trainee’s interests and skill set. If you are interested in learning how you might become involved in one or more of our research projects, please contact the faculty member leading each project (see descriptions of each project below).<\/p>\n
\n\t\tFor Those Interested in Participating in Research\n\t<\/h3>\n\t
Our currently active research studies are listed below. Some studies focus on novel treatments\/clinical trials, while others do not involve treatment per se. As you read through the description of each study, you will find the name and contact information of a research assistant working on each study. If you are interested in participating in one or more of our research projects, please call the research assistant listed for the study.<\/p>\n
\n\t\tAdults\n\t<\/h2>\n\t\t\t\t\tCognitive Remediation of Executive Deficits in Geriatric Depression (Neuroplasticity)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study\u00a0is testing a computer-based program designed to improve mood, memory, and cognitive function in older adults who suffer from depression.<\/p>\n
Recruiting adults ages 55 and older who:<\/p>\n
\n- Have symptoms of depression.<\/li>\n
- Have tried antidepressants in the past and felt like they never got them to a non-depressed state.<\/li>\n
- Have not been diagnosed with dementia or mild cognitive impairment.<\/li>\n
- Are able to read and write in English.<\/li>\n<\/ul>\n
Participation involves:<\/p>\n
\n- Treatment: Over four weeks, participants will complete 32 hours of a computer-based program at home, which involves playing “brain games” on a tablet the study team provides. Participants will be randomly assigned to one of two programs designed to enhance brain activity.<\/li>\n
- Assessments: Baseline, four weekly intervention assessments, and four follow-up assessments to measure mood and thinking abilities. Most take place at UConn Health in Farmington, CT.<\/li>\n
- Cost & Compensation: Participation is free, with up to $275 compensation.<\/li>\n<\/ul>\n
Payment to participants includes: $50 for the baseline evaluation, $25 for each select weekly assessments (weeks 1, 2, and 3), $50 for week 4 assessments, $50 for 3-month post-intervention assessments, and $50 for 1-year post-intervention assessments for a total of up to $275 for the 14-month research study.<\/p>\n
Principal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
To learn more about the study, please contact Frances Jaynes at\u00a0860-679-7948<\/a>\u00a0or email us at\u00a0jaynes@uchc.edu<\/a>.<\/p>\nIRB Number: 022-008-1<\/p>\n
Enrollment end date: April 30, 2026<\/em><\/p>\n\t\t\t\t\tComputerized Cognitive Remediation of Post-Viral Neurocognitive Dysfunction in Older Adults (Cognitive Remediation)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tAre you 60 or older and experiencing memory or thinking problems that started or worsened after getting COVID-19?<\/strong><\/p>\nIf these cognitive symptoms have lasted for at least 12 weeks<\/strong> after your COVID-19 illness, you may be eligible to participate in a research study investigating whether brain-training exercises can help treat Long COVID memory and thinking concerns.<\/p>\nWho can participate?<\/strong><\/p>\n\n- Adults aged 60 years or older<\/strong><\/li>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
What does the study involve?<\/strong><\/p>\nParticipants will be randomly assigned to one of two groups (with a 2:1 ratio):<\/p>\n
\n- Active brain-training exercises<\/strong><\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
Participation takes approximately 43-48 hours over 7 months<\/strong>, with most activities (40-46 hours) completed within the first 7-8 weeks, including:<\/p>\n\n- Initial intake visit:<\/strong> Eligibility confirmation (~2-3 hours)<\/li>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Weekly remote check-in meetings:<\/strong> ~30 minutes each during treatment<\/li>\n
- Blood draws:<\/strong> Two sessions (before and after treatment), ~20-30 minutes each<\/li>\n
- Three research visits:<\/strong> Pre-treatment, post-treatment, and 6-month follow-up (~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)<\/li>\n<\/ul>\n
Location & Participation Details<\/strong><\/p>\n\n- Computer activities and weekly check-ins are done remotely, from the comfort of your home.<\/li>\n
- Research visits and blood draws take place in-person at UConn Health, Farmington, CT.<\/li>\n
- There is no cost to participate.<\/li>\n<\/ul>\n
Compensation<\/strong><\/p>\nParticipants receive up to $160 total:<\/p>\n
\n- $60 after the initial intake visit<\/li>\n
- $60 after the post-treatment visit<\/li>\n
- $40 after the 6-month follow-up visit<\/li>\n<\/ul>\n
Principal Investigator: Cutter Lindbergh, Ph.D., Department of Psychiatry<\/p>\n
To learn more about this study, call Holly Eddy at 860-679-3751<\/a> or email eddy@uchc.edu<\/a>.<\/p>\nIRB Number: 25-389-2<\/p>\n
Enrollment end date: February 28, 2030<\/em><\/p>\n\t\t\t\t\tDual Reinforcement Contingency Management for Alcohol Use Disorders<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study is to help people reduce drinking and could lead to better methods of treating substance abuse. Participants can earn $344 for their time, which consists of brief weekly visits with a research assistant for 3 months and 6 interviews over 12 months. The study also includes the submission of breath, urine, and finger-prick blood samples periodically throughout treatment and follow-up phases. You may qualify if you are in an Intensive Outpatient Program (IOP) for alcohol use.<\/p>\n
Principal Investigator: Sheila Alessi, Ph.D.<\/p>\n
Who to Contact: Amy Novotny,\u00a0860-989-7105<\/a>,\u00a0anovotny@uchc.edu<\/a><\/p>\nIRB Number: 19-146-2<\/p>\n
End date: May 2024<\/em><\/p>\n\t\t\t\t\tEnroll-HD (Huntington’s Disease)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t![\"Enroll-HD](\"https:\/\/health.uconn.edu\/psychiatry\/wp-content\/uploads\/sites\/262\/2021\/05\/enrollHD_300x115.png\")
The UConn Health Huntington’s Disease Program is participating in a study called Enroll-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort (Enroll-HD). Enroll-HD is a worldwide Huntington’s disease (HD) observational, multi-center study.<\/p>\n
The primary objective of Enroll-HD is to improve the understanding of the disease mechanisms of HD by collecting data from families affected by HD in an effort to improve our understanding and treatment of the disease.<\/p>\n
There are no potential therapies or invasive procedures in this study.<\/p>\n
Any member of a family affected by HD can take part. This includes:<\/p>\n
\n- Individuals who know they carry the expanded gene, whether they show signs and symptoms of the disease.<\/li>\n
- Individuals who are at risk of developing the disease (but have not undergone genetic testing).<\/li>\n
- Individuals who have a family history of HD but know they do not carry the expanded gene.<\/li>\n
- Spouses\/partners (not blood related) of family members with HD.<\/li>\n<\/ul>\n
Children under the age of 18 with clinically diagnosed juvenile HD may be included in this study with the consent of a parent or legal guardian.<\/p>\n
Enroll HD is an open ended study, which means it has no definite end time, but you can leave at any time you choose. You will attend one study visit each year.<\/p>\n
For more information about this study, contact:<\/p>\nRobin Zingales-Browne, M.S.N., APRN<\/strong>
\nStudy Coordinator
\nHuntington’s Disease Program
\nUConn Health
\n263 Farmington Avenue
\nFarmington, CT 06030\nPhone: 860-679-4441<\/a>
\nFax: 860-679-1945\n\n\t\tFamilies With Children\n\t<\/h2>\n\t\t\t\t\tChild Anxiety Learning Modules (CALM)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tCALM is a research study funded by the U.S. Department of Education. In the study, elementary school nurses are trained to help support students struggling with anxiety.<\/p>\n
Currently, the CALM study is enrolling school nurses interested in training to support students and families with children who may benefit from learning skills to better manage anxiety. More detailed information is provided below, and please feel free to contact us to learn more.<\/p>\n
Contact the CALM Team at 860-523-3788<\/a> or CALM@uchc.edu<\/a>.<\/p>\n
\nFor Elementary School Nurses<\/h2>\nEnhancing the Capacity of School Nurses to Reduce Child Anxiety (CALM)<\/h3>\n
What is this study about?<\/strong><\/p>\nThis research study was funded by the U.S. Department of Education’s Institute of Education Sciences to compare two interventions to reduce anxiety symptoms and improve academic functioning in 5- to 12-year-old children. Both interventions are brief, evidence-based, and delivered by school nurses in 5 to 6 sessions of 20 to 30 minutes each.<\/p>\n
Why should you volunteer for this study?<\/strong><\/p>\n\n- Learn strategies to help students who are struggling with anxiety<\/li>\n
- Receive free training and supervision<\/li>\n
- Receive copies of the intervention manual and handouts to use with youth<\/li>\n
- Receive financial compensation for completing study requirements (up to $225 in your first year)<\/li>\n<\/ul>\n
What will you be asked to do?<\/strong><\/p>\n\n- Attend one-day virtual training (usually during the weekend or after school)<\/li>\n
- Recruit students with excessive anxiety from your school<\/li>\n
- Deliver the brief intervention to students (5 to 6 meetings)<\/li>\n
- Receive supervision\/consultation from the CALM Team (virtual)<\/li>\n
- Complete study questionnaires<\/li>\n<\/ul>\nHere’s what school nurses said about CALM:<\/strong>
\n“To all, it’s been a pleasure and privilege to be part of this project. Thank you.”\n“Thank you so much for this invaluable experience. I am a better practitioner because of it.”<\/p>\n
“The handouts are phenomenal, and the clinical supervision was wonderful.”<\/p>\n
100% of participating nurses said they would recommend the CALM program.<\/em><\/p>\n
\nFor Families of Children Ages 5 to 12 Who May Be Experiencing Anxiety<\/h2>\n\n- Is your child very nervous, anxious, or shy?<\/li>\n
- Does your child seem afraid, worried, or stressed?<\/li>\n
- Your school nurse may be able to help.<\/li>\n<\/ul>\n
What is the goal of this study?<\/strong><\/p>\nThe aim of this research study is to compare two versions of a brief nurse-administered intervention called Children’s Anxiety Learning Modules (CALM) to reduce anxiety and improve academic functioning. The research is being conducted in U.S. schools. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\nChildren ages 5 to 12 years old whose worry or anxiety makes life hard for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n\n- You and your child will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, you will randomly be assigned to receive 1 of 2 free interventions for anxiety from the school nurse. Interventions include 5 to 6 brief (20 to 30 minutes) student-nurse sessions to learn effective coping skills (1 in 5 students will wait 8 weeks before starting the intervention).<\/li>\n
- You and your child will meet with study staff 2 more times after the intervention so we can see if your child’s anxiety has improved.<\/li>\n
- Families may earn up to $140 in gift cards for participating.<\/li>\n<\/ul>\n
Want to find out more?\u00a0<\/strong>Contact the CALM Team at\u00a0860-523-3788<\/a> or CALM@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 21-037-2<\/p>\n
Funded By: U.S. Department of Education<\/p>\n
End date: May 2025<\/em><\/p>\n\t\t\t\t\tManaging Anxiety in Pediatric Primary Care (MAPP)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tMAPP is a research study funded by the National Institute of Mental Health. In the study, primary care providers are trained to help support youth struggling with anxiety.<\/p>\n
Currently, the MAPP study is enrolling primary care providers interested in learning skills to manage anxiety better to support youth in their practices. More detailed information is provided below. Please feel free to contact us to learn more.<\/p>\n
Contact the MAPP Team at\u00a0860-523-3786<\/a>\u00a0or\u00a0MAPP@uchc.edu<\/a>.<\/p>\n
\nFor Primary Care Providers<\/h2>\nManaging Anxiety in Pediatric Primary Care (MAPP)<\/h3>\n
What is this study about?<\/strong><\/p>\nThis study is funded by the National Institute of Mental Health to test a brief primary care provider (PCP; nurses, pediatricians, physician assistants) administered intervention to reduce anxiety symptoms and related impairment. This study is for youth 6-17 years old.<\/p>\n
Why should PCPs volunteer for this study?<\/strong><\/p>\n\n- Learn strategies to help youth who are struggling with anxiety<\/li>\n
- Receive gift cards for training and coaching<\/li>\n
- Receive copies of the intervention manual and handouts to use with youth<\/li>\n<\/ul>\n
\n- Receive financial compensation for completing study requirements<\/li>\n<\/ul>\n
What will PCPS be asked to do?<\/strong><\/p>\n\n- Attend a 3-hour virtual or in-person training (training sessions are very flexible)<\/li>\n
- Recruit youth with excessive anxiety from your clinic or practice<\/li>\n
- Deliver the brief intervention to youth (approximately 4 meetings)<\/li>\n
- Receive coaching from the MAPP Team (virtual)<\/li>\n
- Complete study questionnaires<\/li>\n<\/ul>\n
Here’s what primary care providers said about MAPP:<\/strong><\/p>\n“I cannot think of anything that has not been great.”<\/p>\n
“So exciting!! Exactly was we need!”<\/p>\n
“Amazing training! Thanks for boiling CBT down in tid bits that can be done in primary care.”<\/p>\n
\nFor Families of Children Ages 6 to 17 Who May Be Experiencing Anxiety<\/h2>\n\n- Is your child very nervous, anxious, or shy?<\/li>\n
- Does your child seem afraid, worried, or stressed?<\/li>\n
- Your pediatric primary care provider may be able to help.<\/li>\n<\/ul>\n
What is the goal of this study?<\/strong><\/p>\nThe aim of this research study is to compare usual care to a brief intervention administered by your youth’s primary care provider to reduce anxiety. The research is being conducted in U.S. clinics. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\nChildren aged 6 to 17 years old whose worry or anxiety makes life hard for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n\n- You and your child will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, you will be randomly assigned (like flipping a coin) to either the enhanced usual care group (written resources on anxiety reduction strategies) or the MAPP intervention group (approximately 4 meetings with your PCP to learn how to reduce anxiety).<\/li>\n
- You and your child will meet with study staff 2 more times after the intervention so we can see if your child’s anxiety has improved.<\/li>\n
- Families may earn up to $220 in gift cards for participating.<\/li>\n<\/ul>\n
Want to find out more? <\/strong>Contact the MAPP Team at\u00a0860-523-3786<\/a>\u00a0or\u00a0MAPP@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 23-111SO-2<\/p>\n
Funded By: National Institute of Mental Health<\/p>\n
End date: May 2025<\/em><\/p>\n\t\t\t\t\tTransitioning Emotionally and Academically to Middle School Successfully (TEAMSS)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t<\/a>Is your child very worried, anxious, or stressed about the transition to middle school?<\/strong><\/p>\nA new program called TEAMSS (Transitioning Emotionally and Academically to Middle School Successfully) may be able to help.<\/p>\n
What is TEAMSS?<\/strong><\/p>\nTEAMSS is a research study designed to develop and assess a multi-component intervention to reduce anxiety and improve academic functioning through the transition to middle school. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\nStudents in their last year of elementary school who will be transitioning to middle school and whose worry\/anxiety makes life harder for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n\n- Parents and children will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, your child will meet with their middle school clinician for a school tour in their last year of elementary school. They will also receive written material on tips for a successful transition to middle school. At the start of middle school, students will meet in a group (with other students (about 6-7 times over 10 weeks) virtually or at their school.<\/li>\n
- School clinicians will host two parent group meeting and will consult with your child’s teacher about how to lower anxiety and succeed in a smooth transition to middles school.<\/li>\n
- You and your child will complete a total of 4 assessments (virtually or in person based on your preference with study staff) before and after the intervention.<\/li>\n
- Your participation in the study will be approximately 12 months.<\/li>\n<\/ul>\n
Are there benefits or compensation?<\/strong><\/p>\n\n- We do not know if your child will benefit from being in this study, but your child may learn new ways to cope with life’s stressors and feel less scared and worried.<\/li>\n
- You and your child can receive up to $70 in gift cards for your participation for completing all 4 study evaluations.<\/li>\n<\/ul>\n
For more information, contact the TEAMSS study team at 860-523-6441<\/a> or TEAMSS@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 22-114OS-1<\/p>\n
Funded by: U.S. Department of Education<\/p>\n\t\t\t\t\tYouth Recovery Program<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tNo-Cost Treatment for Alcohol and\/or Substance Use<\/strong><\/p>\nUConn Health offers treatment to help youthful individuals who may have a problem with alcohol and\/or substances.<\/p>\n
\n- Individuals between the ages of 14-21 may be eligible.<\/li>\n
- The study includes two individual and eight group therapy sessions.<\/li>\n
- Gift cards up to $250 may be offered as compensation.<\/li>\n<\/ul>\n
View more information about the Youth Recovery Program.<\/a><\/p>\n\n\t\tOlder Adults\n\t<\/h2>\n\n\t\tMood, Cognition, and Aging Research\n\t<\/h4>\n\t\t\t\t\tCognitive Remediation of Executive Deficits in Geriatric Depression (Neuroplasticity)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study\u00a0is testing a computer-based program designed to improve mood, memory, and cognitive function in older adults who suffer from depression.<\/p>\n
Recruiting adults ages 55 and older who:<\/p>\n
\n- Have symptoms of depression.<\/li>\n
- Have tried antidepressants in the past and felt like they never got them to a non-depressed state.<\/li>\n
- Have not been diagnosed with dementia or mild cognitive impairment.<\/li>\n
- Are able to read and write in English.<\/li>\n<\/ul>\n
Participation involves:<\/p>\n
\n- Treatment: Over four weeks, participants will complete 32 hours of a computer-based program at home, which involves playing “brain games” on a tablet the study team provides. Participants will be randomly assigned to one of two programs designed to enhance brain activity.<\/li>\n
- Assessments: Baseline, four weekly intervention assessments, and four follow-up assessments to measure mood and thinking abilities. Most take place at UConn Health in Farmington, CT.<\/li>\n
- Cost & Compensation: Participation is free, with up to $275 compensation.<\/li>\n<\/ul>\n
Payment to participants includes: $50 for the baseline evaluation, $25 for each select weekly assessments (weeks 1, 2, and 3), $50 for week 4 assessments, $50 for 3-month post-intervention assessments, and $50 for 1-year post-intervention assessments for a total of up to $275 for the 14-month research study.<\/p>\n
Principal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
To learn more about the study, please contact Frances Jaynes at\u00a0860-679-7948<\/a>\u00a0or email us at\u00a0jaynes@uchc.edu<\/a>.<\/p>\nIRB Number: 022-008-1<\/p>\n
Enrollment end date: April 30, 2026<\/em><\/p>\n\t\t\t\t\tComputerized Cognitive Remediation of Post-Viral Neurocognitive Dysfunction in Older Adults (Cognitive Remediation)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tAre you 60 or older and experiencing memory or thinking problems that started or worsened after getting COVID-19?<\/strong><\/p>\nIf these cognitive symptoms have lasted for at least 12 weeks<\/strong> after your COVID-19 illness, you may be eligible to participate in a research study investigating whether brain-training exercises can help treat Long COVID memory and thinking concerns.<\/p>\nWho can participate?<\/strong><\/p>\n\n- Adults aged 60 years or older<\/strong><\/li>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
What does the study involve?<\/strong><\/p>\nParticipants will be randomly assigned to one of two groups (with a 2:1 ratio):<\/p>\n
\n- Active brain-training exercises<\/strong><\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
Participation takes approximately 43-48 hours over 7 months<\/strong>, with most activities (40-46 hours) completed within the first 7-8 weeks, including:<\/p>\n\n- Initial intake visit:<\/strong> Eligibility confirmation (~2-3 hours)<\/li>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Weekly remote check-in meetings:<\/strong> ~30 minutes each during treatment<\/li>\n
- Blood draws:<\/strong> Two sessions (before and after treatment), ~20-30 minutes each<\/li>\n
- Three research visits:<\/strong> Pre-treatment, post-treatment, and 6-month follow-up (~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)<\/li>\n<\/ul>\n
Location & Participation Details<\/strong><\/p>\n\n- Computer activities and weekly check-ins are done remotely, from the comfort of your home.<\/li>\n
- Research visits and blood draws take place in-person at UConn Health, Farmington, CT.<\/li>\n
- There is no cost to participate.<\/li>\n<\/ul>\n
Compensation<\/strong><\/p>\nParticipants receive up to $160 total:<\/p>\n
\n- $60 after the initial intake visit<\/li>\n
- $60 after the post-treatment visit<\/li>\n
- $40 after the 6-month follow-up visit<\/li>\n<\/ul>\n
Principal Investigator: Cutter Lindbergh, Ph.D., Department of Psychiatry<\/p>\n
To learn more about this study, call Holly Eddy at 860-679-3751<\/a> or email eddy@uchc.edu<\/a>.<\/p>\nIRB Number: 25-389-2<\/p>\n
Enrollment end date: February 28, 2030<\/em><\/p>\n\t\t\t\t\tApathy and Reward Systems in Alzheimer’s Disease<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study seeks to understand cognitive and brain changes related to apathy (loss of interest and motivation) in early Alzheimer’s disease versus depression.<\/p>\n
Recruiting men and women ages 65 to 85 who have:<\/p>\n
\n- Early-stage Alzheimer’s disease or mild cognitive impairment<\/li>\n<\/ul>\n
or<\/p>\n
\n- Depression<\/li>\n<\/ul>\n
Participation involves:<\/p>\n
\n- 4 to 7 appointments at UConn Health.<\/li>\n
- One-time blood draw.<\/li>\n
- Interviews and evaluations.<\/li>\n
- Testing of thinking and memory.<\/li>\n
- One-time MRI brain scan.<\/li>\n
- No cost for participation.<\/li>\n
- During COVID-19, most appointments can be done remotely<\/li>\n<\/ul>\n
Payment to participants includes $100 at completion of the baseline assessment, $100 at completion of the 12-month assessments, and $75 at completion of the 24-month assessments for a total of up to $285 for the 2-year study.<\/p>\n
To learn more about the study, contact Darlene Winkelman at 860-679-8935<\/a> or winkelman@uchc.edu<\/a> or Suzanne Crumb at 860-679-8497<\/a> or crumb@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
IRB Number: 19-214-1<\/p>\n
Participation involves:<\/p>\n
- \n
- Treatment: Over four weeks, participants will complete 32 hours of a computer-based program at home, which involves playing “brain games” on a tablet the study team provides. Participants will be randomly assigned to one of two programs designed to enhance brain activity.<\/li>\n
- Assessments: Baseline, four weekly intervention assessments, and four follow-up assessments to measure mood and thinking abilities. Most take place at UConn Health in Farmington, CT.<\/li>\n
- Cost & Compensation: Participation is free, with up to $275 compensation.<\/li>\n<\/ul>\n
Payment to participants includes: $50 for the baseline evaluation, $25 for each select weekly assessments (weeks 1, 2, and 3), $50 for week 4 assessments, $50 for 3-month post-intervention assessments, and $50 for 1-year post-intervention assessments for a total of up to $275 for the 14-month research study.<\/p>\n
Principal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
To learn more about the study, please contact Frances Jaynes at\u00a0860-679-7948<\/a>\u00a0or email us at\u00a0jaynes@uchc.edu<\/a>.<\/p>\n
IRB Number: 022-008-1<\/p>\n
Enrollment end date: April 30, 2026<\/em><\/p>\n\t\t\t\t\tComputerized Cognitive Remediation of Post-Viral Neurocognitive Dysfunction in Older Adults (Cognitive Remediation)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
Are you 60 or older and experiencing memory or thinking problems that started or worsened after getting COVID-19?<\/strong><\/p>\n
If these cognitive symptoms have lasted for at least 12 weeks<\/strong> after your COVID-19 illness, you may be eligible to participate in a research study investigating whether brain-training exercises can help treat Long COVID memory and thinking concerns.<\/p>\n
Who can participate?<\/strong><\/p>\n
- \n
- Adults aged 60 years or older<\/strong><\/li>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
What does the study involve?<\/strong><\/p>\n
Participants will be randomly assigned to one of two groups (with a 2:1 ratio):<\/p>\n
- \n
- Active brain-training exercises<\/strong><\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
Participation takes approximately 43-48 hours over 7 months<\/strong>, with most activities (40-46 hours) completed within the first 7-8 weeks, including:<\/p>\n
- \n
- Initial intake visit:<\/strong> Eligibility confirmation (~2-3 hours)<\/li>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Weekly remote check-in meetings:<\/strong> ~30 minutes each during treatment<\/li>\n
- Blood draws:<\/strong> Two sessions (before and after treatment), ~20-30 minutes each<\/li>\n
- Three research visits:<\/strong> Pre-treatment, post-treatment, and 6-month follow-up (~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)<\/li>\n<\/ul>\n
Location & Participation Details<\/strong><\/p>\n
- \n
- Computer activities and weekly check-ins are done remotely, from the comfort of your home.<\/li>\n
- Research visits and blood draws take place in-person at UConn Health, Farmington, CT.<\/li>\n
- There is no cost to participate.<\/li>\n<\/ul>\n
Compensation<\/strong><\/p>\n
Participants receive up to $160 total:<\/p>\n
- \n
- $60 after the initial intake visit<\/li>\n
- $60 after the post-treatment visit<\/li>\n
- $40 after the 6-month follow-up visit<\/li>\n<\/ul>\n
Principal Investigator: Cutter Lindbergh, Ph.D., Department of Psychiatry<\/p>\n
To learn more about this study, call Holly Eddy at 860-679-3751<\/a> or email eddy@uchc.edu<\/a>.<\/p>\n
IRB Number: 25-389-2<\/p>\n
Enrollment end date: February 28, 2030<\/em><\/p>\n\t\t\t\t\tDual Reinforcement Contingency Management for Alcohol Use Disorders<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
This study is to help people reduce drinking and could lead to better methods of treating substance abuse. Participants can earn $344 for their time, which consists of brief weekly visits with a research assistant for 3 months and 6 interviews over 12 months. The study also includes the submission of breath, urine, and finger-prick blood samples periodically throughout treatment and follow-up phases. You may qualify if you are in an Intensive Outpatient Program (IOP) for alcohol use.<\/p>\n
Principal Investigator: Sheila Alessi, Ph.D.<\/p>\n
Who to Contact: Amy Novotny,\u00a0860-989-7105<\/a>,\u00a0anovotny@uchc.edu<\/a><\/p>\n
IRB Number: 19-146-2<\/p>\n
End date: May 2024<\/em><\/p>\n\t\t\t\t\tEnroll-HD (Huntington’s Disease)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
The UConn Health Huntington’s Disease Program is participating in a study called Enroll-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort (Enroll-HD). Enroll-HD is a worldwide Huntington’s disease (HD) observational, multi-center study.<\/p>\nThe primary objective of Enroll-HD is to improve the understanding of the disease mechanisms of HD by collecting data from families affected by HD in an effort to improve our understanding and treatment of the disease.<\/p>\n
There are no potential therapies or invasive procedures in this study.<\/p>\n
Any member of a family affected by HD can take part. This includes:<\/p>\n
- \n
- Individuals who know they carry the expanded gene, whether they show signs and symptoms of the disease.<\/li>\n
- Individuals who are at risk of developing the disease (but have not undergone genetic testing).<\/li>\n
- Individuals who have a family history of HD but know they do not carry the expanded gene.<\/li>\n
- Spouses\/partners (not blood related) of family members with HD.<\/li>\n<\/ul>\n
Children under the age of 18 with clinically diagnosed juvenile HD may be included in this study with the consent of a parent or legal guardian.<\/p>\n
Enroll HD is an open ended study, which means it has no definite end time, but you can leave at any time you choose. You will attend one study visit each year.<\/p>\n
For more information about this study, contact:<\/p>\nRobin Zingales-Browne, M.S.N., APRN<\/strong>
\nStudy Coordinator
\nHuntington’s Disease Program
\nUConn Health
\n263 Farmington Avenue
\nFarmington, CT 06030\nPhone: 860-679-4441<\/a>
\nFax: 860-679-1945\n\n\t\tFamilies With Children\n\t<\/h2>\n\t\t\t\t\tChild Anxiety Learning Modules (CALM)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
CALM is a research study funded by the U.S. Department of Education. In the study, elementary school nurses are trained to help support students struggling with anxiety.<\/p>\n
Currently, the CALM study is enrolling school nurses interested in training to support students and families with children who may benefit from learning skills to better manage anxiety. More detailed information is provided below, and please feel free to contact us to learn more.<\/p>\n
Contact the CALM Team at 860-523-3788<\/a> or CALM@uchc.edu<\/a>.<\/p>\n
\nFor Elementary School Nurses<\/h2>\n
Enhancing the Capacity of School Nurses to Reduce Child Anxiety (CALM)<\/h3>\n
What is this study about?<\/strong><\/p>\n
This research study was funded by the U.S. Department of Education’s Institute of Education Sciences to compare two interventions to reduce anxiety symptoms and improve academic functioning in 5- to 12-year-old children. Both interventions are brief, evidence-based, and delivered by school nurses in 5 to 6 sessions of 20 to 30 minutes each.<\/p>\n
Why should you volunteer for this study?<\/strong><\/p>\n
- \n
- Learn strategies to help students who are struggling with anxiety<\/li>\n
- Receive free training and supervision<\/li>\n
- Receive copies of the intervention manual and handouts to use with youth<\/li>\n
- Receive financial compensation for completing study requirements (up to $225 in your first year)<\/li>\n<\/ul>\n
What will you be asked to do?<\/strong><\/p>\n
- \n
- Attend one-day virtual training (usually during the weekend or after school)<\/li>\n
- Recruit students with excessive anxiety from your school<\/li>\n
- Deliver the brief intervention to students (5 to 6 meetings)<\/li>\n
- Receive supervision\/consultation from the CALM Team (virtual)<\/li>\n
- Complete study questionnaires<\/li>\n<\/ul>\nHere’s what school nurses said about CALM:<\/strong>
\n“To all, it’s been a pleasure and privilege to be part of this project. Thank you.”\n“Thank you so much for this invaluable experience. I am a better practitioner because of it.”<\/p>\n
“The handouts are phenomenal, and the clinical supervision was wonderful.”<\/p>\n
100% of participating nurses said they would recommend the CALM program.<\/em><\/p>\n
\nFor Families of Children Ages 5 to 12 Who May Be Experiencing Anxiety<\/h2>\n
- \n
- Is your child very nervous, anxious, or shy?<\/li>\n
- Does your child seem afraid, worried, or stressed?<\/li>\n
- Your school nurse may be able to help.<\/li>\n<\/ul>\n
What is the goal of this study?<\/strong><\/p>\n
The aim of this research study is to compare two versions of a brief nurse-administered intervention called Children’s Anxiety Learning Modules (CALM) to reduce anxiety and improve academic functioning. The research is being conducted in U.S. schools. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\n
Children ages 5 to 12 years old whose worry or anxiety makes life hard for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n
- \n
- You and your child will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, you will randomly be assigned to receive 1 of 2 free interventions for anxiety from the school nurse. Interventions include 5 to 6 brief (20 to 30 minutes) student-nurse sessions to learn effective coping skills (1 in 5 students will wait 8 weeks before starting the intervention).<\/li>\n
- You and your child will meet with study staff 2 more times after the intervention so we can see if your child’s anxiety has improved.<\/li>\n
- Families may earn up to $140 in gift cards for participating.<\/li>\n<\/ul>\n
Want to find out more?\u00a0<\/strong>Contact the CALM Team at\u00a0860-523-3788<\/a> or CALM@uchc.edu<\/a>.<\/p>\n
Principal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 21-037-2<\/p>\n
Funded By: U.S. Department of Education<\/p>\n
End date: May 2025<\/em><\/p>\n\t\t\t\t\tManaging Anxiety in Pediatric Primary Care (MAPP)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
MAPP is a research study funded by the National Institute of Mental Health. In the study, primary care providers are trained to help support youth struggling with anxiety.<\/p>\n
Currently, the MAPP study is enrolling primary care providers interested in learning skills to manage anxiety better to support youth in their practices. More detailed information is provided below. Please feel free to contact us to learn more.<\/p>\n
Contact the MAPP Team at\u00a0860-523-3786<\/a>\u00a0or\u00a0MAPP@uchc.edu<\/a>.<\/p>\n
\nFor Primary Care Providers<\/h2>\n
Managing Anxiety in Pediatric Primary Care (MAPP)<\/h3>\n
What is this study about?<\/strong><\/p>\n
This study is funded by the National Institute of Mental Health to test a brief primary care provider (PCP; nurses, pediatricians, physician assistants) administered intervention to reduce anxiety symptoms and related impairment. This study is for youth 6-17 years old.<\/p>\n
Why should PCPs volunteer for this study?<\/strong><\/p>\n
- \n
- Learn strategies to help youth who are struggling with anxiety<\/li>\n
- Receive gift cards for training and coaching<\/li>\n
- Receive copies of the intervention manual and handouts to use with youth<\/li>\n<\/ul>\n
- \n
- Receive financial compensation for completing study requirements<\/li>\n<\/ul>\n
What will PCPS be asked to do?<\/strong><\/p>\n
- \n
- Attend a 3-hour virtual or in-person training (training sessions are very flexible)<\/li>\n
- Recruit youth with excessive anxiety from your clinic or practice<\/li>\n
- Deliver the brief intervention to youth (approximately 4 meetings)<\/li>\n
- Receive coaching from the MAPP Team (virtual)<\/li>\n
- Complete study questionnaires<\/li>\n<\/ul>\n
Here’s what primary care providers said about MAPP:<\/strong><\/p>\n
“I cannot think of anything that has not been great.”<\/p>\n
“So exciting!! Exactly was we need!”<\/p>\n
“Amazing training! Thanks for boiling CBT down in tid bits that can be done in primary care.”<\/p>\n
\nFor Families of Children Ages 6 to 17 Who May Be Experiencing Anxiety<\/h2>\n
- \n
- Is your child very nervous, anxious, or shy?<\/li>\n
- Does your child seem afraid, worried, or stressed?<\/li>\n
- Your pediatric primary care provider may be able to help.<\/li>\n<\/ul>\n
What is the goal of this study?<\/strong><\/p>\n
The aim of this research study is to compare usual care to a brief intervention administered by your youth’s primary care provider to reduce anxiety. The research is being conducted in U.S. clinics. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\n
Children aged 6 to 17 years old whose worry or anxiety makes life hard for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n
- \n
- You and your child will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, you will be randomly assigned (like flipping a coin) to either the enhanced usual care group (written resources on anxiety reduction strategies) or the MAPP intervention group (approximately 4 meetings with your PCP to learn how to reduce anxiety).<\/li>\n
- You and your child will meet with study staff 2 more times after the intervention so we can see if your child’s anxiety has improved.<\/li>\n
- Families may earn up to $220 in gift cards for participating.<\/li>\n<\/ul>\n
Want to find out more? <\/strong>Contact the MAPP Team at\u00a0860-523-3786<\/a>\u00a0or\u00a0MAPP@uchc.edu<\/a>.<\/p>\n
Principal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 23-111SO-2<\/p>\n
Funded By: National Institute of Mental Health<\/p>\n
End date: May 2025<\/em><\/p>\n\t\t\t\t\tTransitioning Emotionally and Academically to Middle School Successfully (TEAMSS)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
<\/a>Is your child very worried, anxious, or stressed about the transition to middle school?<\/strong><\/p>\n
A new program called TEAMSS (Transitioning Emotionally and Academically to Middle School Successfully) may be able to help.<\/p>\n
What is TEAMSS?<\/strong><\/p>\n
TEAMSS is a research study designed to develop and assess a multi-component intervention to reduce anxiety and improve academic functioning through the transition to middle school. There is no medication involved in this study.<\/p>\n
Who is eligible?<\/strong><\/p>\n
Students in their last year of elementary school who will be transitioning to middle school and whose worry\/anxiety makes life harder for them.<\/p>\n
What is involved in participating in this study?<\/strong><\/p>\n
- \n
- Parents and children will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\n
- If eligible, your child will meet with their middle school clinician for a school tour in their last year of elementary school. They will also receive written material on tips for a successful transition to middle school. At the start of middle school, students will meet in a group (with other students (about 6-7 times over 10 weeks) virtually or at their school.<\/li>\n
- School clinicians will host two parent group meeting and will consult with your child’s teacher about how to lower anxiety and succeed in a smooth transition to middles school.<\/li>\n
- You and your child will complete a total of 4 assessments (virtually or in person based on your preference with study staff) before and after the intervention.<\/li>\n
- Your participation in the study will be approximately 12 months.<\/li>\n<\/ul>\n
Are there benefits or compensation?<\/strong><\/p>\n
- \n
- We do not know if your child will benefit from being in this study, but your child may learn new ways to cope with life’s stressors and feel less scared and worried.<\/li>\n
- You and your child can receive up to $70 in gift cards for your participation for completing all 4 study evaluations.<\/li>\n<\/ul>\n
For more information, contact the TEAMSS study team at 860-523-6441<\/a> or TEAMSS@uchc.edu<\/a>.<\/p>\n
Principal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\n
IRB Number: 22-114OS-1<\/p>\n
Funded by: U.S. Department of Education<\/p>\n\t\t\t\t\tYouth Recovery Program<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
No-Cost Treatment for Alcohol and\/or Substance Use<\/strong><\/p>\n
UConn Health offers treatment to help youthful individuals who may have a problem with alcohol and\/or substances.<\/p>\n
- \n
- Individuals between the ages of 14-21 may be eligible.<\/li>\n
- The study includes two individual and eight group therapy sessions.<\/li>\n
- Gift cards up to $250 may be offered as compensation.<\/li>\n<\/ul>\n
View more information about the Youth Recovery Program.<\/a><\/p>\n
\n\t\tOlder Adults\n\t<\/h2>\n
\n\t\tMood, Cognition, and Aging Research\n\t<\/h4>\n\t\t\t\t\tCognitive Remediation of Executive Deficits in Geriatric Depression (Neuroplasticity)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
This study\u00a0is testing a computer-based program designed to improve mood, memory, and cognitive function in older adults who suffer from depression.<\/p>\n
Recruiting adults ages 55 and older who:<\/p>\n
- \n
- Have symptoms of depression.<\/li>\n
- Have tried antidepressants in the past and felt like they never got them to a non-depressed state.<\/li>\n
- Have not been diagnosed with dementia or mild cognitive impairment.<\/li>\n
- Are able to read and write in English.<\/li>\n<\/ul>\n
Participation involves:<\/p>\n
- \n
- Treatment: Over four weeks, participants will complete 32 hours of a computer-based program at home, which involves playing “brain games” on a tablet the study team provides. Participants will be randomly assigned to one of two programs designed to enhance brain activity.<\/li>\n
- Assessments: Baseline, four weekly intervention assessments, and four follow-up assessments to measure mood and thinking abilities. Most take place at UConn Health in Farmington, CT.<\/li>\n
- Cost & Compensation: Participation is free, with up to $275 compensation.<\/li>\n<\/ul>\n
Payment to participants includes: $50 for the baseline evaluation, $25 for each select weekly assessments (weeks 1, 2, and 3), $50 for week 4 assessments, $50 for 3-month post-intervention assessments, and $50 for 1-year post-intervention assessments for a total of up to $275 for the 14-month research study.<\/p>\n
Principal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
To learn more about the study, please contact Frances Jaynes at\u00a0860-679-7948<\/a>\u00a0or email us at\u00a0jaynes@uchc.edu<\/a>.<\/p>\n
IRB Number: 022-008-1<\/p>\n
Enrollment end date: April 30, 2026<\/em><\/p>\n\t\t\t\t\tComputerized Cognitive Remediation of Post-Viral Neurocognitive Dysfunction in Older Adults (Cognitive Remediation)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
Are you 60 or older and experiencing memory or thinking problems that started or worsened after getting COVID-19?<\/strong><\/p>\n
If these cognitive symptoms have lasted for at least 12 weeks<\/strong> after your COVID-19 illness, you may be eligible to participate in a research study investigating whether brain-training exercises can help treat Long COVID memory and thinking concerns.<\/p>\n
Who can participate?<\/strong><\/p>\n
- \n
- Adults aged 60 years or older<\/strong><\/li>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
What does the study involve?<\/strong><\/p>\n
Participants will be randomly assigned to one of two groups (with a 2:1 ratio):<\/p>\n
- \n
- Active brain-training exercises<\/strong><\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
Participation takes approximately 43-48 hours over 7 months<\/strong>, with most activities (40-46 hours) completed within the first 7-8 weeks, including:<\/p>\n
- \n
- Initial intake visit:<\/strong> Eligibility confirmation (~2-3 hours)<\/li>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Weekly remote check-in meetings:<\/strong> ~30 minutes each during treatment<\/li>\n
- Blood draws:<\/strong> Two sessions (before and after treatment), ~20-30 minutes each<\/li>\n
- Three research visits:<\/strong> Pre-treatment, post-treatment, and 6-month follow-up (~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)<\/li>\n<\/ul>\n
Location & Participation Details<\/strong><\/p>\n
- \n
- Computer activities and weekly check-ins are done remotely, from the comfort of your home.<\/li>\n
- Research visits and blood draws take place in-person at UConn Health, Farmington, CT.<\/li>\n
- There is no cost to participate.<\/li>\n<\/ul>\n
Compensation<\/strong><\/p>\n
Participants receive up to $160 total:<\/p>\n
- \n
- $60 after the initial intake visit<\/li>\n
- $60 after the post-treatment visit<\/li>\n
- $40 after the 6-month follow-up visit<\/li>\n<\/ul>\n
Principal Investigator: Cutter Lindbergh, Ph.D., Department of Psychiatry<\/p>\n
To learn more about this study, call Holly Eddy at 860-679-3751<\/a> or email eddy@uchc.edu<\/a>.<\/p>\n
IRB Number: 25-389-2<\/p>\n
Enrollment end date: February 28, 2030<\/em><\/p>\n\t\t\t\t\tApathy and Reward Systems in Alzheimer’s Disease<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t
This study seeks to understand cognitive and brain changes related to apathy (loss of interest and motivation) in early Alzheimer’s disease versus depression.<\/p>\n
Recruiting men and women ages 65 to 85 who have:<\/p>\n
- \n
- Early-stage Alzheimer’s disease or mild cognitive impairment<\/li>\n<\/ul>\n
or<\/p>\n
- \n
- Depression<\/li>\n<\/ul>\n
Participation involves:<\/p>\n
- \n
- 4 to 7 appointments at UConn Health.<\/li>\n
- One-time blood draw.<\/li>\n
- Interviews and evaluations.<\/li>\n
- Testing of thinking and memory.<\/li>\n
- One-time MRI brain scan.<\/li>\n
- No cost for participation.<\/li>\n
- During COVID-19, most appointments can be done remotely<\/li>\n<\/ul>\n
Payment to participants includes $100 at completion of the baseline assessment, $100 at completion of the 12-month assessments, and $75 at completion of the 24-month assessments for a total of up to $285 for the 2-year study.<\/p>\n
To learn more about the study, contact Darlene Winkelman at 860-679-8935<\/a> or winkelman@uchc.edu<\/a> or Suzanne Crumb at 860-679-8497<\/a> or crumb@uchc.edu<\/a>.<\/p>\n
Principal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\n
IRB Number: 19-214-1<\/p>\n
- Depression<\/li>\n<\/ul>\n
- Early-stage Alzheimer’s disease or mild cognitive impairment<\/li>\n<\/ul>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
- Adults aged 60 years or older<\/strong><\/li>\n
- Receive financial compensation for completing study requirements<\/li>\n<\/ul>\n
- Computer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\n
- Alternative computer activities<\/strong><\/li>\n<\/ul>\n
- Experiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\n
- Adults aged 60 years or older<\/strong><\/li>\n
![<\/a>Is your child very worried, anxious, or stressed about the transition to middle school?<\/strong><\/p>\nA new program called TEAMSS (Transitioning Emotionally and Academically to Middle School Successfully) may be able to help.<\/p>\nWhat is TEAMSS?<\/strong><\/p>\nTEAMSS is a research study designed to develop and assess a multi-component intervention to reduce anxiety and improve academic functioning through the transition to middle school. There is no medication involved in this study.<\/p>\nWho is eligible?<\/strong><\/p>\nStudents in their last year of elementary school who will be transitioning to middle school and whose worry\/anxiety makes life harder for them.<\/p>\nWhat is involved in participating in this study?<\/strong><\/p>\n\nParents and children will meet with study staff virtually or in person for a free evaluation to see if this study is right for your child.<\/li>\nIf eligible, your child will meet with their middle school clinician for a school tour in their last year of elementary school. They will also receive written material on tips for a successful transition to middle school. At the start of middle school, students will meet in a group (with other students (about 6-7 times over 10 weeks) virtually or at their school.<\/li>\nSchool clinicians will host two parent group meeting and will consult with your child’s teacher about how to lower anxiety and succeed in a smooth transition to middles school.<\/li>\nYou and your child will complete a total of 4 assessments (virtually or in person based on your preference with study staff) before and after the intervention.<\/li>\nYour participation in the study will be approximately 12 months.<\/li>\n<\/ul>\nAre there benefits or compensation?<\/strong><\/p>\n\nWe do not know if your child will benefit from being in this study, but your child may learn new ways to cope with life’s stressors and feel less scared and worried.<\/li>\nYou and your child can receive up to $70 in gift cards for your participation for completing all 4 study evaluations.<\/li>\n<\/ul>\nFor more information, contact the TEAMSS study team at 860-523-6441<\/a> or TEAMSS@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: Golda Ginsburg, Ph.D., Department of Psychiatry<\/p>\nIRB Number: 22-114OS-1<\/p>\nFunded by: U.S. Department of Education<\/p>\n\t\t\t\t\tYouth Recovery Program<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tNo-Cost Treatment for Alcohol and\/or Substance Use<\/strong><\/p>\nUConn Health offers treatment to help youthful individuals who may have a problem with alcohol and\/or substances.<\/p>\n\nIndividuals between the ages of 14-21 may be eligible.<\/li>\nThe study includes two individual and eight group therapy sessions.<\/li>\nGift cards up to $250 may be offered as compensation.<\/li>\n<\/ul>\nView more information about the Youth Recovery Program.<\/a><\/p>\n\n\t\tOlder Adults\n\t<\/h2>\n\n\t\tMood, Cognition, and Aging Research\n\t<\/h4>\n\t\t\t\t\tCognitive Remediation of Executive Deficits in Geriatric Depression (Neuroplasticity)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study\u00a0is testing a computer-based program designed to improve mood, memory, and cognitive function in older adults who suffer from depression.<\/p>\nRecruiting adults ages 55 and older who:<\/p>\n\nHave symptoms of depression.<\/li>\nHave tried antidepressants in the past and felt like they never got them to a non-depressed state.<\/li>\nHave not been diagnosed with dementia or mild cognitive impairment.<\/li>\nAre able to read and write in English.<\/li>\n<\/ul>\nParticipation involves:<\/p>\n\nTreatment: Over four weeks, participants will complete 32 hours of a computer-based program at home, which involves playing “brain games” on a tablet the study team provides. Participants will be randomly assigned to one of two programs designed to enhance brain activity.<\/li>\nAssessments: Baseline, four weekly intervention assessments, and four follow-up assessments to measure mood and thinking abilities. Most take place at UConn Health in Farmington, CT.<\/li>\nCost & Compensation: Participation is free, with up to $275 compensation.<\/li>\n<\/ul>\nPayment to participants includes: $50 for the baseline evaluation, $25 for each select weekly assessments (weeks 1, 2, and 3), $50 for week 4 assessments, $50 for 3-month post-intervention assessments, and $50 for 1-year post-intervention assessments for a total of up to $275 for the 14-month research study.<\/p>\nPrincipal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\nTo learn more about the study, please contact Frances Jaynes at\u00a0860-679-7948<\/a>\u00a0or email us at\u00a0jaynes@uchc.edu<\/a>.<\/p>\nIRB Number: 022-008-1<\/p>\nEnrollment end date: April 30, 2026<\/em><\/p>\n\t\t\t\t\tComputerized Cognitive Remediation of Post-Viral Neurocognitive Dysfunction in Older Adults (Cognitive Remediation)<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tAre you 60 or older and experiencing memory or thinking problems that started or worsened after getting COVID-19?<\/strong><\/p>\nIf these cognitive symptoms have lasted for at least 12 weeks<\/strong> after your COVID-19 illness, you may be eligible to participate in a research study investigating whether brain-training exercises can help treat Long COVID memory and thinking concerns.<\/p>\nWho can participate?<\/strong><\/p>\n\nAdults aged 60 years or older<\/strong><\/li>\nExperiencing persistent cognitive symptoms (e.g., memory or thinking difficulties) for 12+ weeks after COVID-19 infection<\/li>\n<\/ul>\nWhat does the study involve?<\/strong><\/p>\nParticipants will be randomly assigned to one of two groups (with a 2:1 ratio):<\/p>\n\nActive brain-training exercises<\/strong><\/li>\nAlternative computer activities<\/strong><\/li>\n<\/ul>\nParticipation takes approximately 43-48 hours over 7 months<\/strong>, with most activities (40-46 hours) completed within the first 7-8 weeks, including:<\/p>\n\nInitial intake visit:<\/strong> Eligibility confirmation (~2-3 hours)<\/li>\nComputer activities:<\/strong> About 5 hours per week for ~6 weeks (total ~30 hours) completed on a tablet provided by the study and loaned to you for use during the treatment phase<\/li>\nWeekly remote check-in meetings:<\/strong> ~30 minutes each during treatment<\/li>\nBlood draws:<\/strong> Two sessions (before and after treatment), ~20-30 minutes each<\/li>\nThree research visits:<\/strong> Pre-treatment, post-treatment, and 6-month follow-up (~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)<\/li>\n<\/ul>\nLocation & Participation Details<\/strong><\/p>\n\nComputer activities and weekly check-ins are done remotely, from the comfort of your home.<\/li>\nResearch visits and blood draws take place in-person at UConn Health, Farmington, CT.<\/li>\nThere is no cost to participate.<\/li>\n<\/ul>\nCompensation<\/strong><\/p>\nParticipants receive up to $160 total:<\/p>\n\n$60 after the initial intake visit<\/li>\n$60 after the post-treatment visit<\/li>\n$40 after the 6-month follow-up visit<\/li>\n<\/ul>\nPrincipal Investigator: Cutter Lindbergh, Ph.D., Department of Psychiatry<\/p>\nTo learn more about this study, call Holly Eddy at 860-679-3751<\/a> or email eddy@uchc.edu<\/a>.<\/p>\nIRB Number: 25-389-2<\/p>\nEnrollment end date: February 28, 2030<\/em><\/p>\n\t\t\t\t\tApathy and Reward Systems in Alzheimer’s Disease<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tThis study seeks to understand cognitive and brain changes related to apathy (loss of interest and motivation) in early Alzheimer’s disease versus depression.<\/p>\nRecruiting men and women ages 65 to 85 who have:<\/p>\n\nEarly-stage Alzheimer’s disease or mild cognitive impairment<\/li>\n<\/ul>\nor<\/p>\n\nDepression<\/li>\n<\/ul>\nParticipation involves:<\/p>\n\n4 to 7 appointments at UConn Health.<\/li>\nOne-time blood draw.<\/li>\nInterviews and evaluations.<\/li>\nTesting of thinking and memory.<\/li>\nOne-time MRI brain scan.<\/li>\nNo cost for participation.<\/li>\nDuring COVID-19, most appointments can be done remotely<\/li>\n<\/ul>\nPayment to participants includes $100 at completion of the baseline assessment, $100 at completion of the 12-month assessments, and $75 at completion of the 24-month assessments for a total of up to $285 for the 2-year study.<\/p>\nTo learn more about the study, contact Darlene Winkelman at 860-679-8935<\/a> or winkelman@uchc.edu<\/a> or Suzanne Crumb at 860-679-8497<\/a> or crumb@uchc.edu<\/a>.<\/p>\nPrincipal Investigator: David Steffens, M.D., Department of Psychiatry<\/p>\nIRB Number: 19-214-1<\/p>\nEnrollment end date: August 1, 2022<\/em><\/p>\nDr. Manning talks about this study and others with the Alzheimer’s Association Connecticut Chapter.<\/a><\/p>\n\n","protected":false},"excerpt":{"rendered":"Research Studies The UConn Health Department of Psychiatry has a large and diverse interdisciplinary research portfolio with multiple studies targeting different psychiatric conditions across the lifespan. 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