Pepper Publications

2024

  • Gasek NS, Yan P, Zhu J, Purushothaman K-R, Kim T, Wang L, Wang B, Flynn WF, Sun M, Guo C, Higgins B, Sharafieh R, Zhou Y, Parizek V, Tchkonia T, Kirkland JL, Wyles SP, Xu M. Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing. Nature Aging. 2024 Nov 13; ahead of print: https://doi.org/10.1038/s43587-024-00755-4
  • Sharafieh R*, Qiao Y, Godlewski I, Czajkowski C, Wu R, Hargis GR, Kreutzer D, Klueh U. Impact of Bindarit, a CCL2 chemokine synthesis inhibitor, on macrophage-based biofouling and continuous glucose monitoring in vivo. Biosensors and Bioelectronics: X. 2024 Aug ahead of print; (19):100511. https://doi.org/10.1016/j.biosx.2024.100511
  • Lindbergh, C. A., Altizer Jr., R., Grady, J. J., Diniz, B. S., Kamath, J., Steffens, D. C., & Morimoto, S. S. (2024). Computerized cognitive remediation of Long COVID in older adults. International Psychogeriatrics, 1-3.
  • Cristina Colón-Semenza, et al. Comparing Physical Activity and Exercise Experiences, Values, and Beliefs of Latino, Latina, and/or Latine People and Non-Latino, Non-Latina, and/or Non-Latine People With Parkinson Disease: A Qualitative Study, Physical Therapy, Volume 104, Issue 10, October 2024, pzae119, https://doi.org/10.1093/ptj/pzae119
  • J. Fanning, T.E. Brinkley, L.M. Campbell, C. Colón-Semenza, S.J. Czaja, R.C. Moore, N.M. Pajewski, S. Kritchevsky. Research Centers Collaborative Network Workshop on Digital Health Approaches to Research in Aging. Innov Aging. 2024 Feb 8;8(2):igae012. doi: 10.1093/geroni/igae012. PMID: 38464460; PMCID: PMC10924449.
  • Steffens, DC, Manning, KJ, Wu R, Ford JD.  Adverse Childhood Experiences and Cognitive Change in Late-Life Depression. American Journal of Geriatric Psychiatry: Open Science, Education, and Practice 2024; 4:1−6

2023

  • Fortinsky RH, Shugrue N, Robison JT, Gitlin LN. The Case for Conducting Pragmatic Dementia Care Trials in Medicaid Home and Community-Based Service Settings. J Am Med Dir Assoc. 2023 Dec;24(12):1918-1923. doi: 10.1016/j.jamda.2023.09.026.
  • Monica M. Nader, Caglar Cosarderelioglu, Emily Miao, Heather Whitson, Qian-Li Xue, Francine Grodstein, Esther Oh, Luigi Ferrucci, David A. Bennett, Jeremy D. Walston, Claudene George, Peter M. Abadir. Navigating and diagnosing cognitive frailty in research and clinical domains. Nat Aging (2023). https://doi.org/10.1038/s43587-023-00504-z
  • Martin DE, Cadar AN, Panier H, Torrance BL, Kuchel GA, Bartley JM. “The Effect of Metformin on Influenza Vaccine Responses in Nondiabetic Older Adults: A Pilot Trial”. Immunity and Ageing. Accepted April 2023.
  • Kathleen K. Mangione, Hope Darreff, McKenna Welsh, Weihong Ni, Edward Wolff, Julie T. Booth, Susan S. Glenney, and Richard H. Fortinsky. Feasibility of a Modified Otago Exercise Program for Older Adults With Cognitive Vulnerability. Journal of Applied Gerontology. 2023, Vol. 0(0) 1–11. PMID: 36919309. DOI: 10.1177/07334648231163050.
  • Kathy Kellett, PhD, Julie Robison, PhD, Heather McAbee-Sevick, MS, Laura N. Gitlin, PhD, FGSA, FAAN, Catherine Verrier Piersol, PhD, OTR/L, FAOTA, and Richard H. Fortinsky, PhD. Implementing the Care of PersonsWith Dementia in Their Environments (COPE) Intervention in Community-Based Programs: Acceptability and Perceived Benefit From Care Managers’ and Interventionists’ Perspectives. The Gerontologist,. 63, 28–39 (2023). doi.org/10.1093/geront/gnac068.

2022

  • Fortinsky RH, Robison J, Steffens DC, Grady J, Migneault D, Wakefield D. Association of Race, Ethnicity, Education, and Neighborhood Context with Dementia Prevalence and Cognitive Impairment Severity among Older Adults receiving Medicaid-funded Home and Community-based Services. American Journal of Geriatric Psychiatry. Doi:10.1016/j.jagp.2022.12.001.
  • Adams KB, Parekh R, Mauldin RL, Fortinsky RH, Steffens DC. The risk for loneliness and major depression among solo agers. Journal of Applied Gerontology. 2022, in press.
  • Steffens, D.C., Fahed, M., Manning, K.J. et al. The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological research. Transl Psychiatry 12, 525 (2022). https://doi.org/10.1038/s41398-022-02292-3
  • Larson PJ, Zhou W, Santiago A, Driscoll S, Fleming E, Voigt AY, Chun OK, Grady JJ, Kuchel GA, Robison JT, Oh J. Associations of the skin, oral and gut microbiome with aging, frailty and infection risk reservoirs in older adults. Nat Aging. 2022 Oct;2(10):941-955. doi: 10.1038/s43587-022-00287-9. Epub 2022 Oct 12. PMID: 36398033; PMCID: PMC9667708.
  • Torrance BL, Haynes L. Cellular senescence is a key mediator of lung aging and susceptibility to infection. Front Immunol. 2022 Aug 31;13:1006710. doi: 10.3389/fimmu.2022.1006710. PMID: 36119079; PMCID: PMC9473698.
  • Lorenzo EC, Torrance BL, Keilich SR, Al-Naggar I, Harrison A, Xu M, Bartley JM, Haynes L. Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics. Aging Cell. 2022 Jan;21(1):e13525. doi: 10.1111/acel.13525. Epub 2021 Dec 27. PMID: 34962049; PMCID: PMC8761018.
    • Andrade AM, Sun M, Gasek NS, Hargis GR, Sharafieh R, Xu M. Role of Senescent Cells in Cutaneous Wound Healing. Biology. 2022; 11(12):1731. https://doi.org/10.3390/biology11121731
    • Lorenzo EC, Kuchel GA, Kuo CL, Moffitt TE, Diniz BS. Major depression and the biological hallmarks of aging. Ageing Res Rev. 2022 Nov 18:101805. doi: 10.1016/j.arr.2022.101805. Epub ahead of print. PMID: 36410621.
    • Diniz, B. S., Lima-Costa, M. F., Peixoto, S. V., Firmo, J., Torres, K., Martins-Filho, O. A., Teixeira-Carvalho, A., Grady, J., Kuchel, G. A., & Castro-Costa, E. (2022). Cognitive Frailty is Associated With Elevated Proinflammatory Markers and a Higher Risk of Mortality. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 30(7), 825–833. https://doi.org/10.1016/j.jagp.2022.01.012
    • Kuffel, R. L., Byers, A. L., Williams, B., Fortinsky, R., Li, Y., Ruderman, M. A., & Barry, L. C. (2022). Prevalence of dementia and mild cognitive impairment before incarceration. Journal of the American Geriatrics Society, 70(6), 1792–1799. https://doi.org/10.1111/jgs.17724
    • Kulkarni AS, Aleksic S, Berger DM, Sierra F, Kuchel GA, Barzilai N. Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization. Aging Cell. 2022 Apr;21(4):e13596. doi: 10.1111/acel.13596. Epub 2022 Mar 27. PMID: 35343051; PMCID: PMC9009114.
    • Lorenzo, E. C., Torrance, B. L., Keilich, S. R., Al-Naggar, I., Harrison, A., Xu, M., Bartley, J. M., & Haynes, L. (2022). Senescence-induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics. Aging cell, 21(1), e13525. https://doi.org/10.1111/acel.13525
    • Masters MC, Landay AL, Robbins PD, Tchkonia T, Kirkland JL, Kuchel GA, Niedernhofer LJ, Palella FJ. Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach. J Acquir Immune Defic Syndr. 2022 Feb 1;89(Suppl 1):S34-S46. doi: 10.1097/QAI.0000000000002858.
    • Picard, E., Armstrong, S., Andrew, M. K., Haynes, L., Loeb, M., Pawelec, G., Kuchel, G. A., McElhaney, J. E., & Verschoor, C. P. (2022). Markers of systemic inflammation are positively associated with influenza vaccine antibody responses with a possible role for ILT2(+)CD57(+) NK-cells. Immunity & ageing : I & A, 19(1), 26. https://doi.org/10.1186/s12979-022-00284-x
    • Soliman G, Fortinsky RH, Mangione KK, Beamer BA, Magder L, Binder EF, Craik R, Gruber-Baldini A, Orwig D, Resnick B, Wakefield DB, Magaziner J. Impact of psychological resilience on walking capacity in older adults following hip fracture. Journal of the American Geriatrics Society 2022. https://doi:10.1111/jgs.17930
    • Wang, L., Wang, B., Gasek, N. S., Zhou, Y., Cohn, R. L., Martin, D. E., Zuo, W., Flynn, W. F., Guo, C., Jellison, E. R., Kim, T., Prata, L., Palmer, A. K., Li, M., Inman, C. L., Barber, L. S., Al-Naggar, I., Zhou, Y., Du, W., Kshitiz, … Xu, M. (2022). Targeting p21Cip1highly expressing cells in adipose tissue alleviates insulin resistance in obesity. Cell metabolism, 34(1), 75–89.e8. https://doi.org/10.1016/j.cmet.2021.11.002

    2021

    • DePalma, A., Noujaim, D., Coman, E., Wakefield, D., & Barry, L. C. (2021). Older incarcerated persons' mental health before and during the COVID-19 pandemic. International journal of prisoner health, ahead-of-print(ahead-of-print), 10.1108/IJPH-08-2021-0077. https://pubmed.ncbi.nlm.nih.gov/34854275/
    • Kannan K, Rogina B. The Role of Citrate Transporter INDY in Metabolism and Stem Cell Homeostasis. Metabolites. 2021 Oct 15;11(10):705. doi: 10.3390/metabo11100705. PMID: 34677421; PMCID: PMC8540898.
    • Sedrak, M. S., Kirkland, J. L., Tchkonia, T., & Kuchel, G. A. (2021). Accelerated aging in older cancer survivors. Journal of the American Geriatrics Society, 69(11), 3077–3080. https://doi.org/10.1111/jgs.17461
    • Verschoor, C. P., Pawelec, G., Haynes, L., Loeb, M., Andrew, M. K., Kuchel, G. A., & McElhaney, J. E. (2021). Granzyme B: a double-edged sword in the response to influenza infection in vaccinated older adults. Frontiers in aging, 2, 753767. https://doi.org/10.3389/fragi.2021.753767