{"id":372,"date":"2018-02-16T11:20:12","date_gmt":"2018-02-16T16:20:12","guid":{"rendered":"https:\/\/health.uconn.edu\/mouse-genome-modification\/?p=372"},"modified":"2018-05-22T08:27:47","modified_gmt":"2018-05-22T12:27:47","slug":"cmgm-mice-on-lead-story-of-uconn-today","status":"publish","type":"post","link":"https:\/\/health.uconn.edu\/mouse-genome-modification\/2018\/02\/16\/cmgm-mice-on-lead-story-of-uconn-today\/","title":{"rendered":"CMGM Mice on Lead Story of UConn Today"},"content":{"rendered":"<figure id=\"attachment_370\" aria-describedby=\"caption-attachment-370\" style=\"width: 640px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-370 size-large\" src=\"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped-1024x683.jpg\" alt=\"Bone-forming cells inside a living bone from a newborn mouse\" width=\"640\" height=\"427\" srcset=\"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped-1024x683.jpg 1024w, https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped-300x200.jpg 300w, https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped-768x512.jpg 768w, https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped-272x182.jpg 272w, https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-content\/uploads\/sites\/134\/2018\/02\/DwarfismPic_cropped.jpg 1137w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><figcaption id=\"caption-attachment-370\" class=\"wp-caption-text\">Bone-forming cells inside a living bone from a newborn mouse. In a recently published study in eLife, Leia Shuhaibar and others at UConn Health showed that these cells produce less cyclic GMP under conditions that resemble those in people with achondroplasia (dwarfism). Understanding how cyclic GMP production is regulated could contribute to improved therapies for achondroplasia. <a href=\"https:\/\/today.uconn.edu\/2018\/02\/fertility-study-offers-unexpected-leads-dwarfism\/\">Read full story.<\/a><\/figcaption><\/figure>\n<p><!--more--><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":249,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"wds_primary_category":0,"footnotes":""},"categories":[1],"tags":[],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-29 17:01:16","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/posts\/372"}],"collection":[{"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/users\/249"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/comments?post=372"}],"version-history":[{"count":7,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/posts\/372\/revisions"}],"predecessor-version":[{"id":560,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/posts\/372\/revisions\/560"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/media?parent=372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/categories?post=372"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/health.uconn.edu\/mouse-genome-modification\/wp-json\/wp\/v2\/tags?post=372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}