Recent Publications

Egbert, J.R, Yee, S.P. and Jaffe, L.A. (2018) Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis. Dev. Biol.,Jan 16 pii:S0012-1606(17)30742-X

Clark, NC, Pru, CA , Yee, SP , Lydon JP , Peluso JJ , Pru, JK (2017) Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence. Endocrinology 158:640-651.

Park, J.W., Yan, L., Stoddard, C., Wang, X., Yue, Z., Crandall, L., Robinson, T., Chang, Y., Denton, K., Li, E., Jiang, B., Zhang, Z., Martins-Taylor, K., Yee, S., Nie, H., Gu, F., Si, W., Xie, T., Yue, L. and Xu, R. (2017) Recapitulating and Correcting Marfan Syndrome in a Cellular Model. Int. J. Biol. Sci. 13:588-603.

Smith, S.S, Samokhin, A.O., Alfadi, M., Murphy, E.C., Rhodes, D., Holcombe, W.M.L., Kiss-Toth, E., Storey, R.F, Yee, S-P., Francis, S.E. and Qwarnstrom, E.E. (2017) The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease. J Am Coll Cardiol Basic Trans Sci. 2:398–414

Shuhaibar, L.C., Robinson J.W., Vigone, G., Shuhaibar, N.P., Egbert, J.R., Baena, V., Uliasz T.F., Kaback, D., Yee, S.P., Feil, R., Fisher, M.C., Dealy, C.N., Potter, L.R., Jaffe, L.A. (2017) Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor. eLife 2017 Dec 4;6. pii: e31343. doi: 10.7554/eLife.31343

Clark NC, Pru CA, Yee SP, Lydon JP, Peluso JJ, Pru JK. Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence. Endocrinology. 2016 Dec 22:en20161701. doi: 10.1210/en.2016-1701. [Epub ahead of print].

McCallum ML, Pru CA, Niikura Y, Yee SP, Lydon JP, Peluso JJ, Pru JK., Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial CystsEndocrinology. 2016 Sep;157(9):3309-19.

Enkhmandakh B, Stoddard C, Mack K, He W, Kaback D, Yee SP, Bayarsaihan D., Generation of a Mouse Model for a Conditional Inactivation of Gtf2i Allele. Genesis. 2016 54:407-12.

Canalis E, Schilling L, Yee SP, Lee SK, Zanotti S., Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis and Bone ResorptionJ Biol Chem. 2016 291:1538-51.

Shuhaibar LC, Egbert JR, Edmund AB, Uliasz TF, Dickey DM, Yee SP, Potter LR, Jaffe LA., Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone. Dev Biol. 2016 Jan 1;409(1):194-201.

Feng ZC, Popell A, Li J, Silverstein J, Oakie A, Yee SP, Wang R., c-Kit Receptor Signaling Regulates Islet Vasculature, b-Cell Survival, and Function In VivoDiabetes.2015 Nov;64(11):3852-66.

Nobuta H, Cilio MR, Danhaive O, Tsai HH, Tupal S, Chang SM, Murnen A, Kreitzer F, Bravo V, Czeisler C, Gokozan HN, Gygli P, Bush S, Weese-Mayer DE, Conklin B, Yee SP, Huang EJ, Gray PA, Rowitch D, Otero JJ., Dysregulation of locus coeruleus development in congenital central hypoventilation syndromeActa Neuropathol. 2015 Aug;130(2):171-83.

Du EX, Wang XF, Yang WC, Kaback D, Yee SP, Qin CL, George A, Hao JJ., Characterization of Fam20C expression in odontogenesis and osteogenesis using transgenic mice. Int J Oral Sci. 2015 Jun 26;7(2):89-94.

Dole NS, Kapinas K, Kessler CB, Yee SP, Adams DJ, Pereira RC, Delany AM., A Single Nucleotide Polymorphism in Osteonectin 3' Untranslated Region Regulates Bone Volume and Is Targeted by miR‐433J Bone Miner Res. 2015 Apr;30(4):723-32.

Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, Bardeesy N, Gingras AC, Yee SP, Screaton RA., Role of the SIK2-p35-PJA2 complex in pancreatic beta cell functional compensation. Nat Cell Biol. 2014 Mar;16(3):234-44. doi: 10.1038/ncb2919. Erratum in: Nat Cell Biol. 2014 Apr;16(4):382.

Feng ZC, Li J, Turco BA, Riopel M, Yee SP, Wang R., Critical role of c-Kit in beta cell function: increased insulin secretion and protection against diabetes in a mouse modelDiabetologia. 2012 Aug;55(8):2214-25.