{"id":20,"date":"2019-04-26T15:19:37","date_gmt":"2019-04-26T19:19:37","guid":{"rendered":"https:\/\/health.uconn.edu\/mok-lab\/?page_id=20"},"modified":"2025-12-16T21:34:45","modified_gmt":"2025-12-17T02:34:45","slug":"publications","status":"publish","type":"page","link":"https:\/\/health.uconn.edu\/mok-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Publications<\/h1>\n<\/div><\/div><\/div><\/div>

Stationary-phase Pseudomonas aeruginosa<\/em> Fluoroquinolone Persisters Mostly Avoid DNA Double-stranded Breaks<\/a>.
\nHare, Patricia J; Gonzalez Juliet R; Mok, Wendy W K mSphere<\/span>. <\/span>2025 Dec 16;<\/span>:e0079325<\/span>.\u00a0<\/span><\/p>\n

Time-Lapse Epifluorescence Microscopy Imaging of Pseudomonas aeruginosa<\/em> and Staphylococcus aureus<\/em> Heterogeneous Phenotypes<\/span><\/a>
\nHare, Patricia J; Batchelder, Jonathan I; LaGree, Travis J; Mahey, Nisha; Power, Angela D; Wu, Yi I; Mok, Wendy W K Journal of Visualized Experiments 2025 February; 216<\/p>\n

Metabolites Augment Oxidative Stress to Sensitize Antibiotic-tolerant Staphylococcus aureus\u00a0<\/em>to Fluoroquinolones<\/a>
\nBatchelder, Jonathan I; Taylor, Andrew J; Mok, Wendy W K mBio 2024 October; e02714-24<\/span><\/p>\n

Agar and Agarose Used for Staphylococcus aureus\u00a0<\/em>Biofilm Cultivation Impact Fluoroquinolone Tolerance<\/a>
\nPower, Angela D; Mok, Wendy W K Journal of Applied Microbiology 2024 August; 135(8):lxae191<\/span><\/p>\n

Metabolic and Transcriptional Activities Underlie Stationary-phase\u00a0Pseudomonas aeruginosa\u00a0<\/em>Sensitivity to Levofloxacin<\/a>
\nHare, Patricia J; Gonzalez Juliet R; Quelle, Ryan M; Wu, Yi I.; Mok, Wendy W K Microbiology Spectrum 2024 January; 12(1):e0356723<\/span><\/p>\n

Lab Culture: How do Scientists Grow and Study Bacteria?<\/a>
\nHare, Patricia J; Mok, Wendy W K Frontiers for Young Minds 2023 Jun<\/p>\n

\"Figure<\/p>\n

Stimulating Transcription in Antibiotic-Tolerant Escherichia coli Sensitizes It to Fluoroquinolone and Nonfluoroquinolone Topoisomerase Inhibitors.<\/a>
\nLaGree, Travis J; Byrd, Brandon A; Quelle, Ryan M; Schofield, Stephanie L; Mok, Wendy W K<\/span> Antimicrobial Agents and Chemotherapy<\/span> 2023 Mar:\u00a0<\/span>e0163922<\/span><\/p>\n

Resistance-resistant Antibacterial Treatment Strategies<\/a>
\nBatchelder, Jonathan I; Hare, Patricia J; Mok, Wendy W K<\/span>\u00a0Frontiers in Antibiotics<\/span> 2023 Jan; doi: 10.3389\/frabi.2023.1093156<\/span><\/span><\/p>\n

Probiotic Escherichia coli Nissle 1917 Inhibits Bacterial Persisters that Survive Fluoroquinolone Treatment<\/a>
\nHare, Patricia J; Englander, Hanna E; Mok, Wendy W K<\/span>\u00a0Journal of Applied Microbiology<\/span> 2022 Mar;\u00a0<\/span>doi: 10.1111\/jam.15541.<\/p>\n

Single-Cell Technologies to Study Phenotypic Heterogeneity and Bacterial Persisters<\/span><\/a>
\nHare, Patricia J; LaGree, Travis J; Byrd, Brandon A; DeMarco, Angela M; Mok, Wendy W K<\/span> Microorganisms<\/span> 2021 Nov;<\/span>9<\/span>(11):<\/span>2277<\/span><\/p>\n

The AcrAB-TolC Efflux Pump Impacts Persistence and Resistance Development in Stationary-Phase Escherichia coli Following Delafloxacin Treatment.<\/a>
\nByrd, Brandon A; Zenick, Blesing; Rocha-Granados, Maria C; Englander, Hanna E; Hare, Patricia J; LaGree, Travis; DeMarco, Angela M; Mok, Wendy W K\u00a0Antimicrobial Agents and Chemotherapy<\/span> 2021 Jun; 65: e0028121<\/span><\/p>\n

Dodecylamine rapidly kills of spores of multiple Firmicute species: properties of the killed spores and the mechanism of the killing.<\/a>
\nDeMarco, A M; Korza, G; Granados, M R; Mok, W W K; Setlow, P Journal of Applied Microbiology<\/span> 2021 May; in press<\/span><\/span><\/p>\n

Levels and Characteristics of mRNAs in Spores of Firmicute Species.<\/a>
\nByrd, Brandon; Camilleri, Emily; Korza, George; Craft, D Levi; Green, Joshua; Rocha Granados, Maria; Mok, Wendy W K; Caimano, Melissa J; Setlow, Peter\u00a0Journal of Bacteriology<\/span> 2021 May; 203: e0001721<\/span><\/p>\n

The social network: Impact of host and microbial interactions on bacterial antibiotic tolerance and persistence.<\/a>
\nRocha-Granados; Maria C; Zenick, Blesing; Englander, Hanna E; Mok, Wendy W K Cellular Signalling<\/span> 2020 Aug; 75:109750<\/span><\/p>\n

Killing of bacterial spores by dodecylamine and its effects on spore inner membrane properties.<\/a>
\nMokashi, S; Kanaan, J; Craft, D L; Byrd, B; Zenick, B; Laue, M; Korza, G; Mok, W W K; Setlow, P Journal of Applied Microbiology<\/span> 2020 Jun; 129(6):1511-1522<\/span><\/p>\n

Lack of efficient killing of purified dormant spores of Bacillales and Clostridiales species by glycerol monolaurate in a non-aqueous gel. <\/a>
\nGreen, J; Korza, G; Granados, M R; Zenick, B; Schlievert, P M; Mok, W W K; Setlow, P Letters in Applied Microbiology<\/span> 2020 Jun; 70(6): 407-412<\/span><\/p>\n

DNA damage\u00a0Kills Bacterial Spores and Cells Exposed to 222 nm UV Radiation.<\/a>
\nTaylor, Willie; Camilleri, Emily; Craft, D Levi; Korza, George; Rocha Granados, Maria; Peterson, Jaliyah; Szczpaniak, Renata; Weller, Sandra K; Moeller, Ralf; Douki,\u00a0Thierry; Mok, Wendy W K; Setlow., Peter Applied Environmental Microbiology\u00a02020 Apr; 86(8): e03039-19<\/p>\n

Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic.<\/a>
\nBarrett, Theresa C; Mok, Wendy W K; Murawski, Allison M; Brynildsen, Mark P\u00a0Nature Communications\u00a02019 Mar;10(1):1177<\/p>\n

Publications Pre-2019:<\/strong><\/p>\n

Timing of DNA damage responses impacts persistence to fluoroquinolones.<\/a>
\nMok, Wendy W K; Brynildsen, Mark P\u00a0Proceedings of the National Academy of Sciences of the United States of America\u00a02018 Jul;115(27):E6301-E6309<\/p>\n

Biased inheritance protects older bacteria from harm.<\/a>
\nBarrett, Theresa C; Mok, Wendy W K; Brynildsen, Mark P\u00a0Science (New York, N.Y.)\u00a02017 Apr;356(6335):247-248<\/p>\n

An Orphan Riboswitch Unveils Guanidine Regulation in Bacteria.<\/a>
\nMok, Wendy W K; Brynildsen, Mark P\u00a0Molecular Cell\u00a02017 Jan;65(2):205-206<\/p>\n

Non-Monotonic Survival of Staphylococcus aureus with Respect to Ciprofloxacin Concentration Arises from Prophage-Dependent Killing of Persisters.<\/a>
\nSandvik, Elizabeth L; Fazen, Christopher H; Henry, Theresa C; Mok, Wendy W K; Brynildsen, Mark P\u00a0Pharmaceuticals (Basel, Switzerland)\u00a02015 Nov;8(4):778-92<\/p>\n

RNA Futile Cycling in Model Persisters Derived from MazF Accumulation.<\/a>
\nMok, Wendy W K; Park, Junyoung O; Rabinowitz, Joshua D; Brynildsen, Mark P\u00a0mBio\u00a02015 Nov;6(6):e01588-15<\/p>\n

Impacts of global transcriptional regulators on persister metabolism.<\/a>
\nMok, Wendy W K; Orman, Mehmet A; Brynildsen, Mark P\u00a0Antimicrobial Agents and Chemotherapy\u00a02015 May;59(5):2713-9<\/p>\n

Aminoglycoside-enabled elucidation of bacterial persister metabolism.<\/a>
\nOrman, Mehmet A; Mok, Wendy W K; Brynildsen, Mark P\u00a0Current Protocols in Microbiology\u00a02015 Feb;3617.9.1-14<\/p>\n

A highly efficient molecular cloning platform that utilises a small bacterial toxin gene.<\/a>
\nMok, Wendy W K; Li, Yingfu\u00a0Chembiochem : a European Journal of Chemical Biology\u00a02013 Apr;14(6):733-8<\/p>\n

Developing fluorogenic RNA-cleaving DNAzymes for biosensing applications.<\/a>
\nAli, M Monsur; Aguirre, Sergio D; Mok, Wendy W K; Li, Yingfu\u00a0Methods in Molecular Biology (Clifton, N.J.)\u00a02012 Jan;848395-418<\/p>\n

Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli.<\/a>
\nMok, Wendy W K; Patel, Nirav H; Li, Yingfu\u00a0The Journal of Biological Chemistry\u00a02010 Dec;285(53):41627-36<\/p>\n

Characterization of an RNA-cleaving deoxyribozyme with optimal activity at pH 5.<\/a>
\nKandadai, Srinivas A; Mok, Wendy W K; Ali, Md Monsur; Li, Yingfu\u00a0Biochemistry\u00a02009 Aug;48(31):7383-91<\/p>\n

Identification of a toxic peptide through bidirectional expression of small RNAs.<\/a>
\nMok, Wendy W K; Navani, Naveen K; Barker, Courtney; Sawchyn, Bobbijo L; Gu, Jimmy; Pathania, Ranjana; Zhu, Rebecca D; Brown, Eric D; Li, Yingfu\u00a0Chembiochem : a European Journal of Chemical Biology\u00a02009 Jan;10(2):238-41<\/p>\n

In vitro selection of protein-binding DNA aptamers as ligands for biosensing applications.<\/a>
\nNavani, Naveen K; Mok, Wing Ki; Yingfu, Li\u00a0Methods in Molecular Biology (Clifton, N.J.)\u00a02009 Jan;504399-415<\/p>\n

Non-molecular-clock-like evolution following viral origins in homo sapiens.<\/a>
\nMok, Wendy; Seto, Kelly; Stone, Jon\u00a0Evolutionary Bioinformatics Online\u00a02007 Sep;3263-6<\/p>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Publications Stationary-phase Pseudomonas aeruginosa Fluoroquinolone Persisters Mostly Avoid DNA Double-stranded Breaks. Hare, Patricia J; Gonzalez Juliet R; Mok, Wendy W K mSphere. 2025 Dec 16;:e0079325.\u00a0 Time-Lapse Epifluorescence Microscopy Imaging of Pseudomonas aeruginosa and Staphylococcus aureus Heterogeneous Phenotypes Hare, Patricia J; Batchelder, Jonathan I; LaGree, Travis J; Mahey, Nisha; Power, Angela D; Wu, Yi I; Mok, […]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-blank.php","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-13 13:26:47","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/pages\/20"}],"collection":[{"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/users\/38"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/comments?post=20"}],"version-history":[{"count":33,"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/pages\/20\/revisions"}],"predecessor-version":[{"id":528,"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/pages\/20\/revisions\/528"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/mok-lab\/wp-json\/wp\/v2\/media?parent=20"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}