Cancer cells tend to hoard iron, and ovarian cancer cells in particular. They take in more iron than normal cells, and they release less of it. UConn Health postdoctoral fellow in computational biology Anna Konstorum, director of the Center for Quantitative Medicine Reinhard Laubenbacher, and their colleagues wondered why. Perhaps cancer cells’ iron habit was a weakness doctors could use against the disease. Read more.
At a time when the danger of opioids is clear, UConn Health and The Jackson Laboratory (JAX) are collaborating to form the Connecticut Pain Consortium.
Professor Reinhard Laubenbacher, who will lead the consortium and is a joint faculty member at UConn Health and The Jackson Laboratory, said the consortium will focus on researching the causes of pain, as well as pain management and how to translate that research into new therapies. Read more.
Professor Reinhard Laubenbacher from the UConn School of Medicine Department of Cell Biology, Director of the Center for Quantitative Medicine and Professor at The Jackson Laboratory for Genomic Medicine, Dr. Pedro Mendes also in the Department of Cell Biology and the Center for Quantitative Medicine, and Dr. Anna Dongari-Bagtzoglou, chair of the Division of Periodontology UConn School of Dental Medicine, have been awarded more than $2.2 million from the National Institutes of Health, to study ways by which we may be able to control biofilms formed by a fungus that is an important cause of topical and systemic infections. Read more.
UConn Health, UConn Schools of Medicine and Nursing, and The Jackson Laboratory have announced the creation of the Connecticut Pain Consortium, a translational pain research and education collaboration which is the first of its kind in the Connecticut medical community. The consortium will be led by Professor Dr. Reinhard Laubenbacher, a joint faculty member at UConn Health and JAX. “There is a clear need for more basic and translational research on human pain and pain management,” said Dr. Laubenbacher. “And, there is a critical unmet need for education and training of providers and patients. This is a great opportunity to deploy our capabilities in addiction and pain research together with our Connecticut partners in an exciting and much needed state-wide initiative.” Read more
Drs. Reinhard Laubenbacher and Pedro Mendes of the Center for Quantitative Medicine, and Dr. Anna Dongari-Bagtzoglou of The Division of Periodontology UConn School of Dental Medicine, have been awarded over $2.20 million over the next four years from the National Institutes of Health (NIH) for “Control of heterogeneous microbial communities using model-based multi-objective optimization” (1R01GM127909-01). A novel mathematical approach to an important use of Agent-based models (ABMs) as a means to model-based control biological system. Rather than viewing the ABM as a model, it is to be viewed as a surrogate for the actual system.