{"id":3253,"date":"2024-03-28T07:05:51","date_gmt":"2024-03-28T11:05:51","guid":{"rendered":"https:\/\/health.uconn.edu\/immunology\/2024\/03\/28\/dr-sivapriya-kailasan-vanaja-and-ms-skylar-wrights-paper-published-in-cell-reports-2\/"},"modified":"2024-03-28T07:05:51","modified_gmt":"2024-03-28T11:05:51","slug":"dr-sivapriya-kailasan-vanaja-and-ms-skylar-wrights-paper-published-in-cell-reports-2","status":"publish","type":"post","link":"https:\/\/health.uconn.edu\/immunology\/2024\/03\/28\/dr-sivapriya-kailasan-vanaja-and-ms-skylar-wrights-paper-published-in-cell-reports-2\/","title":{"rendered":"Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright&#8217;s Paper Published in Cell Reports"},"content":{"rendered":"<div id=\"pl-3253\"  class=\"panel-layout\" ><div id=\"pg-3253-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-3253-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-3253-0-0-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"textwidget\"><p>Congratulations Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright for having their paper, \u201cA bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis\u201d \u00a0published in the journal Cell Reports. The paper, first-authored by Ms. Skylar Wright, a graduate student, identified a novel molecular mechanism by which a clinically significant human pathogen, Enterohemorrhagic E. coli, utilizes its virulence factor, Shiga toxin, to effectively suppress host protective noncanonical inflammasome responses.<\/p>\n<\/div><\/div><\/div><div id=\"pgc-3253-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-3253-0-1-0\" class=\"so-panel widget widget_widget_sp_image widget_sp_image panel-first-child panel-last-child\" data-index=\"1\" ><h3 class=\"widget-title\"> <\/h3><img loading=\"lazy\" decoding=\"async\" width=\"350\" height=\"200\" alt=\"Dr. Kailasan Vanaja and Skylar Wright\" class=\"attachment-full\" style=\"max-width: 100%;\" src=\"https:\/\/health.uconn.edu\/immunology\/wp-content\/uploads\/sites\/67\/2024\/02\/Kailasan-Photo.gif\" \/><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Congratulations Dr. Sivapriya Kailasan Vanaja and Ms. Skylar Wright for having their paper, \u201cA bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis\u201d \u00a0published in the journal Cell Reports. The paper, first-authored by Ms. Skylar Wright, a graduate student, identified a novel molecular mechanism by which a clinically significant human pathogen, [&hellip;]<\/p>\n","protected":false},"author":1662,"featured_media":3184,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"wds_primary_category":0,"footnotes":""},"categories":[1],"tags":[],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-30 09:33:00","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts\/3253"}],"collection":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/users\/1662"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/comments?post=3253"}],"version-history":[{"count":0,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts\/3253\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/media\/3184"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/media?parent=3253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/categories?post=3253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/tags?post=3253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}