{"id":3041,"date":"2023-10-26T07:05:51","date_gmt":"2023-10-26T11:05:51","guid":{"rendered":"https:\/\/health.uconn.edu\/immunology\/2023\/10\/26\/dr-kepeng-wangs-paper-published-in-apsb-2-2\/"},"modified":"2023-10-26T07:05:51","modified_gmt":"2023-10-26T11:05:51","slug":"dr-kepeng-wangs-paper-published-in-apsb-2-2","status":"publish","type":"post","link":"https:\/\/health.uconn.edu\/immunology\/2023\/10\/26\/dr-kepeng-wangs-paper-published-in-apsb-2-2\/","title":{"rendered":"Dr. Kepeng Wang&#8217;s Paper Published in APSB"},"content":{"rendered":"<div id=\"pl-3041\"  class=\"panel-layout\" ><div id=\"pg-3041-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-3041-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-3041-0-0-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"textwidget\"><p>Congratulations to Dr. Kepeng Wang for having his paper, \u201cCancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12,\u00a0 IL-17 and PD-L1 pathways to prevent tumor recurrence\u201d published in Acta Pharmaceutica Sinica B (APSB). The paper describes a novel oncolytic viral therapy for cancers that incorporates payloads targeting IL-12, IL-17, and PD-L1 signaling. Successful eradication of established colon and liver tumors in mouse models points to the agent\u2019s potential in future clinical use in humans. Former postdoctoral fellow Dr. Ju Chen from Dr. Kepeng Wang\u2019s lab is the leading author of the publication.\u00a0 Please use this link to access the publication: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383523003416\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211383523003416<\/a><\/p>\n<\/div><\/div><\/div><div id=\"pgc-3041-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-3041-0-1-0\" class=\"so-panel widget widget_widget_sp_image widget_sp_image panel-first-child panel-last-child\" data-index=\"1\" ><h3 class=\"widget-title\"> <\/h3><img loading=\"lazy\" decoding=\"async\" width=\"350\" height=\"200\" alt=\"Dr. Kepeng Wang\" class=\"attachment-full\" style=\"max-width: 100%;\" src=\"https:\/\/health.uconn.edu\/immunology\/wp-content\/uploads\/sites\/67\/2023\/08\/photo_wang_kepeng-350-x-200-1.gif\" \/><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Congratulations to Dr. Kepeng Wang for having his paper, \u201cCancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12,\u00a0 IL-17 and PD-L1 pathways to prevent tumor recurrence\u201d published in Acta Pharmaceutica Sinica B (APSB). The paper describes a novel oncolytic viral therapy for cancers that incorporates payloads targeting IL-12, IL-17, and PD-L1 signaling. Successful eradication [&hellip;]<\/p>\n","protected":false},"author":1662,"featured_media":2919,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"wds_primary_category":0,"footnotes":""},"categories":[1],"tags":[],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-01 18:02:14","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts\/3041"}],"collection":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/users\/1662"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/comments?post=3041"}],"version-history":[{"count":0,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/posts\/3041\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/media\/2919"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/media?parent=3041"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/categories?post=3041"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/health.uconn.edu\/immunology\/wp-json\/wp\/v2\/tags?post=3041"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}