The Institute for Regenerative Engineering recently published a new textbook, Regenerative Engineering of Musculoskeletal Tissues and Interfaces. Published by Woodhead Publishing Ltd, this comprehensive book looks at individual musculoskeletal tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Late chapters present information on musculoskeletal tissue interfaces. As the chief editor, I want to express my gratitude first and foremost to all our contributors and especially, my co-editors, Drs. Joseph Freeman and Syam Nukavarapu, for their tireless efforts and time to edit this book.