The Institute for Regenerative Engineering has published the landmark book Bone Graft Substitutes and Bone Regenerative Engineering. The book provides a well-rounded and articulate summary of the present status of using allogeneic, xenogenic, and synthetic bone graft substitutes to reconstruct bone tissues. To reflect on the importance of the concept of convergence, Bone Graft Substitutes and Bone Regenerative Engineering captures the excitement of the new field we call Regenerative Engineering. The chapters of the book are written by the leading researchers in academia, surgeons, industry leaders and regulatory specialists. We believe this new book, following the very successful first edition entitled Bone Graft Substitutes, will be of value to people who work in all fields involving bone. I thank Dr. Tao Jiang, my co-editor, for his time and effort in working with me. In addition, the publication of this book would be impossible without the assistance from numerous people at ASTM International. Finally, I also want to thank the Raymond and Beverly Sackler Foundation for their tremendous support in all our efforts to define the new field of Regenerative Engineering.