Publications

Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells.

Wright SS, Kumari P, Fraile-Ágreda V, Wang C, Shivcharan S, Kappelhoff S, Margheritis EG, Matz A, Vasudevan SO, Rubio I, Bauer M, Zhou B, Vanaja SK, Cosentino K, Ruan J, Rathinam VA.Cell. 2025 Jan 23;188(2):280-291.e17. doi: 10.1016/j.cell.2024.11.018. Epub 2024 Dec 31.PMID: 39742811

MACanalyzeR scRNAseq analysis tool reveals PPARγ^HIGH/GDF15^HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT.

Ninni A, Zaccaria F, Verteramo L, Sciarretta F, Silveira LS, Rosa-Neto JC, Carotti S, Nevi L, Grumati P, Patel S, Carrera G, Sgambato A, Lucchetti D, Colella F, Severi I, Senzacqua M, Giordano A, Bernardini S, Di Biagio C, Tortolici F, Rizzo G, Cochain C, Chiurchiù V, Ivanov S, Zhou B, Williams JW, Savage DB, Aquilano K, Lettieri-Barbato D.Nat Commun. 2025 May 31;16(1):5063. doi: 10.1038/s41467-025-60295-2.PMID: 40450001 Free PMC article.

CFTR dictates monocyte adhesion by facilitating integrin clustering but not activation.

Younis DA, Marosvari M, Liu W, Pulikkot S, Cao Z, Zhou B, Vella AT, McArdle S, Hu L, Chen Y, Gan W, Yu J, Bruscia EM, Fan Z.Proc Natl Acad Sci U S A. 2025 Jan 21;122(3):e2412717122. doi: 10.1073/pnas.2412717122. Epub 2025 Jan 15.PMID: 39813254 Free PMC article.

Soluble Immune Checkpoint Protein and Lipid Network Associations with All-Cause Mortality Risk: Trans-Omics for Precision Medicine (TOPMed) Program.

Rodriguez A, Yang C, Gan W, Karlinsey K, Zhou B, Rich SS, Taylor KD, Guo X, Rotter JI, Johnson WC, Cornell E, Tracy RP, Durda JP, Gerszten RE, Clish CB, Blackwell T, Papanicolaou GJ, Lin H, Raffield LM, Vargas JD, Vasan R, Manichaikul A.medRxiv [Preprint]. 2025 Jan 9:2025.01.08.25320225. doi: 10.1101/2025.01.08.25320225.PMID: 39830278 Free PMC article. Preprint.

The immune response within Alzheimer's disease: from the lense of peripheral monocyte-derived macrophages.

LeVasseur H, Zhou B.J Neuroimmunol. 2025 Aug 2;407:578711. doi: 10.1016/j.jneuroim.2025.578711. Online ahead of print.PMID: 40753761

Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells.

Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation.

Karginov TA, Ménoret A, Leclair NK, Harrison AG, Chandiran K, Suarez-Ramirez JE, Yurieva M, Karlinsey K, Wang P, O'Neill RJ, Murphy PA, Adler AJ, Cauley LS, Anczuków O, Zhou B, Vella AT.Science. 2024 Sep 13;385(6714):eadj1979. doi: 10.1126/science.adj1979. Epub 2024 Sep 13.PMID: 39265028 Free PMC article.

Lipid-associated macrophages reshape BAT cell identity in obesity.

Sciarretta F, Ninni A, Zaccaria F, Chiurchiù V, Bertola A, Karlinsey K, Jia W, Ceci V, Di Biagio C, Xu Z, Gaudioso F, Tortolici F, Tiberi M, Zhang J, Carotti S, Boudina S, Grumati P, Zhou B, Brestoff JR, Ivanov S, Aquilano K, Lettieri-Barbato D.Cell Rep. 2024 Jul 23;43(7):114447. doi: 10.1016/j.celrep.2024.114447. Epub 2024 Jul 3.PMID: 38963761 Free PMC article.

Endothelial Immunosuppression in Atherosclerosis : Translational Control by Elavl1/HuR.

Nicholas SE, Helming SR, Ménoret A, Pathoulas C, Xu MM, Hensel J, Kimble AL, Heineman B, Jellison ER, Reese B, Zhou B, Rodriguez-Oquendo A, Vella AT, Murphy PA.bioRxiv [Preprint]. 2024 Aug 4:2024.08.02.605922. doi: 10.1101/2024.08.02.605922.PMID: 39131295 Free PMC article. Preprint.

Microbiome-derived bacterial lipids regulate gene expression of proinflammatory pathway inhibitors in systemic monocytes.

Mihori S, Nichols F, Provatas A, Matz A, Zhou B, Blesso CN, Panier H, Daddi L, Zhou Y, Clark RB.Front Immunol. 2024 Jun 26;15:1415565. doi: 10.3389/fimmu.2024.1415565. eCollection 2024.PMID: 38989285 Free PMC article.

How does obesity potentiate autoimmune disease in women?

Karlinsey K, Zhou B.Obes Med. 2024 Dec;52:100570. doi: 10.1016/j.obmed.2024.100570. Epub 2024 Nov 29.PMID: 39713554 No abstract available.

Capturing the multifaceted function of adipose tissue macrophages.

Matz AJ, Qu L, Karlinsey K, Vella AT, Zhou B.Front Immunol. 2023 Feb 16;14:1148188. doi: 10.3389/fimmu.2023.1148188. eCollection 2023.PMID: 36875144 Free PMC article. Review.

Multifaceted mitochondrial quality control in brown adipose tissue.

Aquilano K, Zhou B, Brestoff JR, Lettieri-Barbato D.Trends Cell Biol. 2023 Jun;33(6):517-529. doi: 10.1016/j.tcb.2022.09.008. Epub 2022 Oct 19.PMID: 36272883 Free PMC article. Review.

Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival.

Ménoret A, Agliano F, Karginov TA, Karlinsey KS, Zhou B, Vella AT.Front Immunol. 2023 Jan 27;14:1102403. doi: 10.3389/fimmu.2023.1102403. eCollection 2023.PMID: 36817480 Free PMC article.

A wonder drug? new discoveries potentiate new therapeutic potentials of metformin.

Matz AJ, Zhou B.Obes Med. 2023 Oct;43:100514. doi: 10.1016/j.obmed.2023.100514. Epub 2023 Oct 6.PMID: 40761706 Free PMC article. No abstract available.

A novel strategy to dissect multifaceted macrophage function in human diseases.
Karlinsey, Keaton; Qu, Lili; Matz, Alyssa J; Zhou, Beiyan Journal of leukocyte biology 2022 Dec;112(6):1535-1542
Macrophages at the Crossroad of Meta-Inflammation and Inflammaging.
Qu, Lili; Matz, Alyssa J; Karlinsey, Keaton; Cao, Ziming; Vella, Anthony T; Zhou, Beiyan Genes 2022 Nov;13(11):
Multifaceted mitochondrial quality control in brown adipose tissue.
Aquilano, Katia; Zhou, Beiyan; Brestoff, Jonathan R; Lettieri-Barbato, Daniele Trends in cell biology 2022 Oct;
Obesity and Adipose Tissue Dysfunction: From Pediatrics to Adults.
Menendez, Ana; Wanczyk, Heather; Walker, Joanne; Zhou, Beiyan; Santos, Melissa; Finck, Christine Genes 2022 Oct;13(10):
MicroRNA-regulated B cells in obesity.
Matz, Alyssa J; Qu, Lili; Karlinsey, Keaton; Zhou, Beiyan Immunometabolism (Cobham (Surrey, England)) 2022 Jul;4(3):e00005
Impact of microRNA Regulated Macrophage Actions on Adipose Tissue Function in Obesity.
Matz, Alyssa; Qu, Lili; Karlinsey, Keaton; Zhou, Beiyan Cells 2022 Apr;11(8):
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina, Marco; Ceci, Veronica; Turchi, Riccardo; Chuan, Li; Borcherding, Nicholas; Sciarretta, Francesca; Sánchez-Díaz, María; Tortolici, Flavia; Karlinsey, Keaton; Chiurchiù, Valerio; Fuoco, Claudia; Giwa, Rocky; Field, Rachael L; Audano, Matteo; Arena, Simona; Palma, Alessandro; Riccio, Federica; Shamsi, Farnaz; Renzone, Giovanni; Verri, Martina; Crescenzi, Anna; Rizza, Salvatore; Faienza, Fiorella; Filomeni, Giuseppe; Kooijman, Sander; Rufini, Stefano; de Vries, Antoine A F; Scaloni, Andrea; Mitro, Nico; Tseng, Yu-Hua; Hidalgo, Andrés; Zhou, Beiyan; Brestoff, Jonathan R; Aquilano, Katia; Lettieri-Barbato, Daniele Cell metabolism 2022 Apr;34(4):533-548.e12
AtheroSpectrum Reveals Novel Macrophage Foam Cell gene Signatures Associated with Atherosclerotic Cardiovascular Disease Risk.
Li, Chuan; Qu, Lili; Matz, Alyssa J; Murphy, Patrick A; Liu, Yongmei; Manichaikul, Ani W; Aguiar, Derek; Rich, Stephen S; Herrington, David M; Vu, David; Johnson, W Craig; Rotter, Jerome I; Post, Wendy S; Vella, Anthony T; Rodriguez-Oquendo, Annabelle; Zhou, Beiyan Circulation 2022 Jan;145(3):206-218
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.
Li, Chuan; Phoon, Yee Peng; Karlinsey, Keaton; Tian, Ye F; Thapaliya, Samjhana; Thongkum, Angkana; Qu, Lili; Matz, Alyssa Joyce; Cameron, Mark; Cameron, Cheryl; Menoret, Antoine; Funchain, Pauline; Song, Jung-Min; Diaz-Montero, C Marcela; Tamilselvan, Banumathi; Golden, Jackelyn B; Cartwright, Michael; Rodriguez, Annabelle; Bonin, Christopher; Vella, Anthony; Zhou, Beiyan; Gastman, Brian R The Journal of experimental medicine 2022 Jan;219(1):

IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong, Genshen; Zhang, Jiaojiao; Guo, Ying; Wang, Yichun; Wu, Minna; Ren, Jie; Li, Yuan; Zhang, Xiaoying; Zhou, Beiyan; Zhao, Weidong; Lou, Yunwei; Wang, Hui; Ye, Jianping International immunopharmacology 2021 Jul;99107980
Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Russo, Ashley J; Vasudevan, Swathy O; Méndez-Huergo, Santiago P; Kumari, Puja; Menoret, Antoine; Duduskar, Shivalee; Wang, Chengliang; Pérez Sáez, Juan M; Fettis, Margaret M; Li, Chuan; Liu, Renjie; Wanchoo, Arun; Chandiran, Karthik; Ruan, Jianbin; Vanaja, Sivapriya Kailasan; Bauer, Michael; Sponholz, Christoph; Hudalla, Gregory A; Vella, Anthony T; Zhou, Beiyan; Deshmukh, Sachin D; Rabinovich, Gabriel A; Rathinam, Vijay A Nature immunology 2021 Feb;22(2):154-165

Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction.
Yu, Fei; Chapman, Samantha; Pham, Dylan Luc; Ko, Michael Lee; Zhou, Beiyan; Ko, Gladys Y-P BMJ open diabetes research & care 2020 Sep;8(1):
STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination.
Lu, Hsueh Chung; Kim, Sunja; Steelman, Andrew J; Tracy, Kevin; Zhou, Beiyan; Michaud, Danielle; Hillhouse, Andrew E; Konganti, Kranti; Li, Jianrong Proceedings of the National Academy of Sciences of the United States of America 2020 Mar;117(10):5430-5441

Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis.
Xiong, Xuelian; Kuang, Henry; Ansari, Sahar; Liu, Tongyu; Gong, Jianke; Wang, Shuai; Zhao, Xu-Yun; Ji, Yewei; Li, Chuan; Guo, Liang; Zhou, Linkang; Chen, Zhimin; Leon-Mimila, Paola; Chung, Meng Ting; Kurabayashi, Katsuo; Opp, Judy; Campos-Pérez, Francisco; Villamil-Ramírez, Hugo; Canizales-Quinteros, Samuel; Lyons, Robert; Lumeng, Carey N; Zhou, Beiyan; Qi, Ling; Huertas-Vazquez, Adriana; Lusis, Aldons J; Xu, X Z Shawn; Li, Siming; Yu, Yonghao; Li, Jun Z; Lin, Jiandie D Molecular cell 2019 Aug;75(3):644-660.e5
MicroRNA Regulated Macrophage Activation in Obesity.
Li, Chuan; Qu, Lili; Farragher, Cullen; Vella, Anthony; Zhou, Beiyan Journal of translational internal medicine 2019 Jun;7(2):46-52
Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases.
Li, Chuan; Menoret, Antoine; Farragher, Cullen; Ouyang, Zhengqing; Bonin, Christopher; Holvoet, Paul; Vella, Anthony T; Zhou, Beiyan JCI insight 2019 Apr;5
Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci.
Xu, Maria Mei; Ménoret, Antoine; Nicholas, Sarah-Anne E; Günther, Sebastian; Sundberg, Eric J; Zhou, Beiyan; Rodriguez, Annabelle; Murphy, Patrick A; Vella, Anthony T American journal of physiology. Heart and circulatory physiology 2019 Apr;
Glutamine Metabolism in Macrophages: A Novel Target for Obesity/Type 2 Diabetes.
Ren, Wenkai; Xia, Yaoyao; Chen, Siyuan; Wu, Guoyao; Bazer, Fuller W; Zhou, Beiyan; Tan, Bie; Zhu, Guoqiang; Deng, Jinping; Yin, Yulong Advances in nutrition (Bethesda, Md.) 2019 Feb;

Understanding how combinatorial targeting of TLRs and TNFR family costimulatory members promote enhanced T cell responses.
Shinde, Paurvi; Bharat, Vinita; Rodriguez-Oquendo, Annabelle; Zhou, Beiyan; Vella, Anthony T Expert opinion on biological therapy 2018 Oct;18(10):1073-1083
Macrophage polarization and meta-inflammation.
Li, Chuan; Xu, Maria M; Wang, Kepeng; Adler, Adam J; Vella, Anthony T; Zhou, Beiyan Translational research : the journal of laboratory and clinical medicine 2018 Jan;19129-44
Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Kim, SunJa; Bielawski, Jacek; Yang, Hyunmin; Kong, Yu; Zhou, Beiyan; Li, Jianrong Glia 2018 Mar;66(3):654-669

IRF6 regulates alternative activation by suppressing PPARγ in male murine macrophages.
Li, Chuan; Ying, Wei; Huang, Zheping; Brehm, Tyler; Morin, Andrew; Vella, Anthony T; Zhou, Beiyan Endocrinology 2017 Jun;1582837-2847
Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic ß-cells for effective management of type 1 diabetes mellitus.
Ganugula, Raghu; Arora, Meenakshi; Jaisamut, Patcharawalai; Wiwattanapatapee, Ruedeekorn; Jørgensen, Heather G; Venkatpurwar, Vinod P; Zhou, Beiyan; Rodrigues Hoffmann, Aline; Basu, Rita; Guo, Shaodong; Ravi Kumar, Majeti N V British journal of pharmacology 2017 Apr;1742074-2084
Cytokines and metabolic factors regulate tumoricidal T-cell function during cancer immunotherapy.
Adler, Adam J; Mittal, Payal; Ryan, Joseph M; Zhou, Beiyan; Wasser, Jeffrey S; Vella, Anthony T Immunotherapy 2017 Jan;9(1):71-82
Roles of arginine in cell-mediated and humoral immunity
Wenkai Ren, Yulong Yin, Beiyan Zhou, Fuller W Bazer, Guoyao Wu Nutrition, Immunity & Infection 2017 Oct;
MicroRNA-regulated immune cell function in obese adipose tissue. (Chapter 26)
Zhou B*, Ying W, Li C, Vella AT Handbook of Nutrition, Diet, and Epigenetics 2017 Jun;
Nutrition, microRNAs, and Human Health.
Cui, Juan; Zhou, Beiyan; Ross, Sharon A; Zempleni, Janos Advances in nutrition (Bethesda, Md.) 2017 Jan;8(1):105-112

Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action.
Yang, Ence; Wang, Gang; Yang, Jizhou; Zhou, Beiyan; Tian, Yanan; Cai, James J Human molecular genetics 2016 Sep;
Data describing the effects of dietary bioactive agents on colonic stem cell microRNA and mRNA expression.
Shah, Manasvi S; Kim, Eunjoo; Davidson, Laurie A; Knight, Jason M; Zoh, Roger S; Goldsby, Jennifer S; Callaway, Evelyn S; Zhou, Beyian; Ivanov, Ivan; Chapkin, Robert S Data in brief 2016 Mar;6398-404
MiR-129 triggers autophagic flux by regulating a novel Notch-1/ E2F7/Beclin-1 axis to impair the viability of human malignant glioma cells.
Chen, Xiong; Zhang, Yingying; Shi, Yingying; Lian, Haiwei; Tu, Huilin; Han, Song; Yin, Jun; Peng, Biwen; Zhou, Beiyan; He, Xiaohua; Liu, Wanhong Oncotarget 2016 Jan;79222-35
Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic crypt.
Shah, Manasvi S; Kim, Eunjoo; Davidson, Laurie A; Knight, Jason M; Zoh, Roger S; Goldsby, Jennifer S; Callaway, Evelyn S; Zhou, Beyian; Ivanov, Ivan; Chapkin, Robert S Biochimica et biophysica acta 2016 Jan;1862(1):121-34
Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice.
Shi, Liheng; Kim, Andy Jeesu; Chang, Richard Cheng-An; Chang, Janet Ya-An; Ying, Wei; Ko, Michael L; Zhou, Beiyan; Ko, Gladys Yi-Ping PloS one 2016 Jan;11(6):e0157543
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Ying, Wei; Tseng, Alexander; Chang, Richard Cheng-An; Wang, Haiqing; Lin, Yu-Lieh; Kanameni, Srikanth; Brehm, Tyler; Morin, Andrew; Jones, Benjamin; Splawn, Taylor; Criscitiello, Michael; Golding, Michael C; Bazer, Fuller W; Safe, Stephen; Zhou, Beiyan Scientific reports 2016 Jan;620176

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
Ying, Wei; Tseng, Alexander; Chang, Richard Cheng-An; Morin, Andrew; Brehm, Tyler; Triff, Karen; Nair, Vijayalekshmi; Zhuang, Guoqing; Song, Hui; Kanameni, Srikanth; Wang, Haiqing; Golding, Michael C; Bazer, Fuller W; Chapkin, Robert S; Safe, Stephen; Zhou, Beiyan The Journal of clinical investigation 2015 Nov;125(11):4149-59
High-Fat Diet-Induced Retinal Dysfunction.
Chang, Richard Cheng-An; Shi, Liheng; Huang, Cathy Chia-Yu; Kim, Andy Jeesu; Ko, Michael L; Zhou, Beiyan; Ko, Gladys Y-P Investigative ophthalmology & visual science 2015 Apr;56(4):2367-80
The many faces of interferon tau.
Bazer, Fuller W; Ying, Wei; Wang, Xiaoqiu; Dunlap, Kathrin A; Zhou, Beiyan; Johnson, Greg A; Wu, Guoyao Amino acids 2015 Mar;47(3):449-60
NR4A Orphan Receptors as Drug Targets
Stephen Safe, Syng-Ook Lee, Cong Meng, Beiyan Zhou Targeted Therapy of Acute Myeloid Leukemia 2015 Jan;
MicroRNA-regulated immune cell function in obese adipose tissue
Wei Ying, Chuan Li, Anthony T Vella, Beiyan Zhou Handbook of Nutrition, Diet, and Epigenetics

Pregnancy-secreted Acid phosphatase, uteroferrin, enhances fetal erythropoiesis.
Ying, Wei; Wang, Haiqing; Bazer, Fuller W; Zhou, Beiyan Endocrinology 2014 Nov;155(11):4521-30
MicroRNA-503 acts as a tumor suppressor in glioblastoma for multiple antitumor effects by targeting IGF-1R.
Zhang, Yingying; Chen, Xiong; Lian, Haiwei; Liu, Jianmiao; Zhou, Beiyan; Han, Song; Peng, Biwen; Yin, Jun; Liu, Wanhong; He, Xiaohua Oncology reports 2014 Mar;31(3):1445-52
Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.
Ying, Wei; Kanameni, Srikanth; Chang, Cheng-An; Nair, Vijayalekshmi; Safe, Stephen; Bazer, Fuller W; Zhou, Beiyan PloS one 2014 Jan;9(6):e98835
MicroRNAs Control Macrophage Formation and Activation: The Inflammatory Link between Obesity and Cardiovascular Diseases.
Chang, Richard Cheng-An; Ying, Wei; Bazer, Fuller W; Zhou, Beiyan Cells 2014 Jan;3(3):702-12
Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression.
Triff, Karen; Konganti, Kranti; Gaddis, Sally; Zhou, Beiyan; Ivanov, Ivan; Chapkin, Robert S Physiological genomics 2013 Dec;45(24):1229-43
miR-150 blocks MLL-AF9-associated leukemia through oncogene repression.
Bousquet, Marina; Zhuang, Guoqing; Meng, Cong; Ying, Wei; Cheruku, Patali S; Shie, Andrew T; Wang, Stephanie; Ge, Guangtao; Wong, Piu; Wang, Gang; Safe, Stephen; Zhou, Beiyan Molecular cancer research : MCR 2013 Aug;11(8):912-22
Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation.
Li, Fen; Yu, Xuan; Szynkarski, Claudia K; Meng, Cong; Zhou, Beiyan; Barhoumi, Rola; White, Richard E; Heaps, Cristine L; Stallone, John N; Han, Guichun PloS one 2013 Jan;8(6):e64771
Investigation of macrophage polarization using bone marrow derived macrophages.
Ying, Wei; Cheruku, Patali S; Bazer, Fuller W; Safe, Stephen H; Zhou, Beiyan Journal of visualized experiments : JoVE 2013 Jan;(76):
A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation.
Zhuang, Guoqing; Meng, Cong; Guo, Xin; Cheruku, Patali S; Shi, Lei; Xu, Hang; Li, Honggui; Wang, Gang; Evans, Ashley R; Safe, Stephen; Wu, Chaodong; Zhou, Beiyan Circulation 2012 Jun;125(23):2892-903
Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.
Shah, Manasvi S; Schwartz, Scott L; Zhao, Chen; Davidson, Laurie A; Zhou, Beiyan; Lupton, Joanne R; Ivanov, Ivan; Chapkin, Robert S Physiological genomics 2011 May;43(10):640-54
MicroRNA miR-125b causes leukemia.
Bousquet, Marina; Harris, Marian H; Zhou, Beiyan; Lodish, Harvey F Proceedings of the National Academy of Sciences of the United States of America 2010 Dec;107(50):21558-63
Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.
Ouyang, N; Ke, S; Eagleton, N; Xie, Y; Chen, G; Laffins, B; Yao, H; Zhou, B; Tian, Y British journal of cancer 2010 Jun;102(12):1753-61
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets.
Le, Minh T N; Xie, Huangming; Zhou, Beiyan; Chia, Poh Hui; Rizk, Pamela; Um, Moonkyoung; Udolph, Gerald; Yang, Henry; Lim, Bing; Lodish, Harvey F Molecular and cellular biology 2009 Oct;29(19):5290-305
MicroRNA-125b is a novel negative regulator of p53.
Le, Minh T N; Teh, Cathleen; Shyh-Chang, Ng; Xie, Huangming; Zhou, Beiyan; Korzh, Vladimir; Lodish, Harvey F; Lim, Bing Genes & development 2009 Apr;23(7):862-76
Micromanagement of the immune system by microRNAs.
Lodish, Harvey F; Zhou, Beiyan; Liu, Gwen; Chen, Chang-Zheng Nature reviews. Immunology 2008 Feb;8(2):120-30
Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.
Liao, Mai-Jing; Zhang, Cheng Cheng; Zhou, Beiyan; Zimonjic, Drazen B; Mani, Sendurai A; Kaba, Megan; Gifford, Ann; Reinhardt, Ferenc; Popescu, Nicholas C; Guo, Wenjun; Eaton, Elinor Ng; Lodish, Harvey F; Weinberg, Robert A Cancer research 2007 Sep;67(17):8131-8
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely.
Zhou, Beiyan; Wang, Stephanie; Mayr, Christine; Bartel, David P; Lodish, Harvey F Proceedings of the National Academy of Sciences of the United States of America 2007 Apr;104(17):7080-5
Analysis of placental regulation of hematopoiesis.
Zhou, Beiyan; Linzer, Daniel I H Methods in molecular medicine 2006 Jan;122355-65
Enhanced recovery from thrombocytopenia and neutropenia in mice constitutively expressing a placental hematopoietic cytokine.
Zhou, Beiyan; Kong, Xiangrong; Linzer, Daniel I H Endocrinology 2005 Jan;146(1):64-70
Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation.
Zhou, Beiyan; Lum, Hillary E; Lin, Jiandie; Linzer, Daniel I H Endocrinology 2002 Nov;143(11):4281-6
A fast, sensitive and specific method for rice dwarf virus detection by northern blot hybridization.
Yu, L; Li, Y; Gu, G; Wang, Y; Zhou, B; An, C; Chen, Z Acta virologica 1999 Dec;43(6):361-5

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