Publications
2022
- A novel strategy to dissect multifaceted macrophage function in human diseases.
Karlinsey, Keaton; Qu, Lili; Matz, Alyssa J; Zhou, Beiyan Journal of leukocyte biology 2022 Dec;112(6):1535-1542
- Macrophages at the Crossroad of Meta-Inflammation and Inflammaging.
Qu, Lili; Matz, Alyssa J; Karlinsey, Keaton; Cao, Ziming; Vella, Anthony T; Zhou, Beiyan Genes 2022 Nov;13(11):
- Multifaceted mitochondrial quality control in brown adipose tissue.
Aquilano, Katia; Zhou, Beiyan; Brestoff, Jonathan R; Lettieri-Barbato, Daniele Trends in cell biology 2022 Oct;
- Obesity and Adipose Tissue Dysfunction: From Pediatrics to Adults.
Menendez, Ana; Wanczyk, Heather; Walker, Joanne; Zhou, Beiyan; Santos, Melissa; Finck, Christine Genes 2022 Oct;13(10):
- MicroRNA-regulated B cells in obesity.
Matz, Alyssa J; Qu, Lili; Karlinsey, Keaton; Zhou, Beiyan Immunometabolism (Cobham (Surrey, England)) 2022 Jul;4(3):e00005
- Impact of microRNA Regulated Macrophage Actions on Adipose Tissue Function in Obesity.
Matz, Alyssa; Qu, Lili; Karlinsey, Keaton; Zhou, Beiyan Cells 2022 Apr;11(8):
- Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina, Marco; Ceci, Veronica; Turchi, Riccardo; Chuan, Li; Borcherding, Nicholas; Sciarretta, Francesca; Sánchez-Díaz, María; Tortolici, Flavia; Karlinsey, Keaton; Chiurchiù, Valerio; Fuoco, Claudia; Giwa, Rocky; Field, Rachael L; Audano, Matteo; Arena, Simona; Palma, Alessandro; Riccio, Federica; Shamsi, Farnaz; Renzone, Giovanni; Verri, Martina; Crescenzi, Anna; Rizza, Salvatore; Faienza, Fiorella; Filomeni, Giuseppe; Kooijman, Sander; Rufini, Stefano; de Vries, Antoine A F; Scaloni, Andrea; Mitro, Nico; Tseng, Yu-Hua; Hidalgo, Andrés; Zhou, Beiyan; Brestoff, Jonathan R; Aquilano, Katia; Lettieri-Barbato, Daniele Cell metabolism 2022 Apr;34(4):533-548.e12
- AtheroSpectrum Reveals Novel Macrophage Foam Cell gene Signatures Associated with Atherosclerotic Cardiovascular Disease Risk.
Li, Chuan; Qu, Lili; Matz, Alyssa J; Murphy, Patrick A; Liu, Yongmei; Manichaikul, Ani W; Aguiar, Derek; Rich, Stephen S; Herrington, David M; Vu, David; Johnson, W Craig; Rotter, Jerome I; Post, Wendy S; Vella, Anthony T; Rodriguez-Oquendo, Annabelle; Zhou, Beiyan Circulation 2022 Jan;145(3):206-218
- A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients.
Li, Chuan; Phoon, Yee Peng; Karlinsey, Keaton; Tian, Ye F; Thapaliya, Samjhana; Thongkum, Angkana; Qu, Lili; Matz, Alyssa Joyce; Cameron, Mark; Cameron, Cheryl; Menoret, Antoine; Funchain, Pauline; Song, Jung-Min; Diaz-Montero, C Marcela; Tamilselvan, Banumathi; Golden, Jackelyn B; Cartwright, Michael; Rodriguez, Annabelle; Bonin, Christopher; Vella, Anthony; Zhou, Beiyan; Gastman, Brian R The Journal of experimental medicine 2022 Jan;219(1):
2021
- IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong, Genshen; Zhang, Jiaojiao; Guo, Ying; Wang, Yichun; Wu, Minna; Ren, Jie; Li, Yuan; Zhang, Xiaoying; Zhou, Beiyan; Zhao, Weidong; Lou, Yunwei; Wang, Hui; Ye, Jianping International immunopharmacology 2021 Jul;99107980
- Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin.
Russo, Ashley J; Vasudevan, Swathy O; Méndez-Huergo, Santiago P; Kumari, Puja; Menoret, Antoine; Duduskar, Shivalee; Wang, Chengliang; Pérez Sáez, Juan M; Fettis, Margaret M; Li, Chuan; Liu, Renjie; Wanchoo, Arun; Chandiran, Karthik; Ruan, Jianbin; Vanaja, Sivapriya Kailasan; Bauer, Michael; Sponholz, Christoph; Hudalla, Gregory A; Vella, Anthony T; Zhou, Beiyan; Deshmukh, Sachin D; Rabinovich, Gabriel A; Rathinam, Vijay A Nature immunology 2021 Feb;22(2):154-165
2020
- Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction.
Yu, Fei; Chapman, Samantha; Pham, Dylan Luc; Ko, Michael Lee; Zhou, Beiyan; Ko, Gladys Y-P BMJ open diabetes research & care 2020 Sep;8(1):
- STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination.
Lu, Hsueh Chung; Kim, Sunja; Steelman, Andrew J; Tracy, Kevin; Zhou, Beiyan; Michaud, Danielle; Hillhouse, Andrew E; Konganti, Kranti; Li, Jianrong Proceedings of the National Academy of Sciences of the United States of America 2020 Mar;117(10):5430-5441
2019
- Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis.
Xiong, Xuelian; Kuang, Henry; Ansari, Sahar; Liu, Tongyu; Gong, Jianke; Wang, Shuai; Zhao, Xu-Yun; Ji, Yewei; Li, Chuan; Guo, Liang; Zhou, Linkang; Chen, Zhimin; Leon-Mimila, Paola; Chung, Meng Ting; Kurabayashi, Katsuo; Opp, Judy; Campos-Pérez, Francisco; Villamil-Ramírez, Hugo; Canizales-Quinteros, Samuel; Lyons, Robert; Lumeng, Carey N; Zhou, Beiyan; Qi, Ling; Huertas-Vazquez, Adriana; Lusis, Aldons J; Xu, X Z Shawn; Li, Siming; Yu, Yonghao; Li, Jun Z; Lin, Jiandie D Molecular cell 2019 Aug;75(3):644-660.e5
- MicroRNA Regulated Macrophage Activation in Obesity.
Li, Chuan; Qu, Lili; Farragher, Cullen; Vella, Anthony; Zhou, Beiyan Journal of translational internal medicine 2019 Jun;7(2):46-52
- Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases.
Li, Chuan; Menoret, Antoine; Farragher, Cullen; Ouyang, Zhengqing; Bonin, Christopher; Holvoet, Paul; Vella, Anthony T; Zhou, Beiyan JCI insight 2019 Apr;5
- Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci.
Xu, Maria Mei; Ménoret, Antoine; Nicholas, Sarah-Anne E; Günther, Sebastian; Sundberg, Eric J; Zhou, Beiyan; Rodriguez, Annabelle; Murphy, Patrick A; Vella, Anthony T American journal of physiology. Heart and circulatory physiology 2019 Apr;
- Glutamine Metabolism in Macrophages: A Novel Target for Obesity/Type 2 Diabetes.
Ren, Wenkai; Xia, Yaoyao; Chen, Siyuan; Wu, Guoyao; Bazer, Fuller W; Zhou, Beiyan; Tan, Bie; Zhu, Guoqiang; Deng, Jinping; Yin, Yulong Advances in nutrition (Bethesda, Md.) 2019 Feb;
2018
- Understanding how combinatorial targeting of TLRs and TNFR family costimulatory members promote enhanced T cell responses.
Shinde, Paurvi; Bharat, Vinita; Rodriguez-Oquendo, Annabelle; Zhou, Beiyan; Vella, Anthony T Expert opinion on biological therapy 2018 Oct;18(10):1073-1083
- Macrophage polarization and meta-inflammation.
Li, Chuan; Xu, Maria M; Wang, Kepeng; Adler, Adam J; Vella, Anthony T; Zhou, Beiyan Translational research : the journal of laboratory and clinical medicine 2018 Jan;19129-44
- Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination.
Kim, SunJa; Bielawski, Jacek; Yang, Hyunmin; Kong, Yu; Zhou, Beiyan; Li, Jianrong Glia 2018 Mar;66(3):654-669
2017
- IRF6 regulates alternative activation by suppressing PPARγ in male murine macrophages.
Li, Chuan; Ying, Wei; Huang, Zheping; Brehm, Tyler; Morin, Andrew; Vella, Anthony T; Zhou, Beiyan Endocrinology 2017 Jun;1582837-2847
- Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic ß-cells for effective management of type 1 diabetes mellitus.
Ganugula, Raghu; Arora, Meenakshi; Jaisamut, Patcharawalai; Wiwattanapatapee, Ruedeekorn; Jørgensen, Heather G; Venkatpurwar, Vinod P; Zhou, Beiyan; Rodrigues Hoffmann, Aline; Basu, Rita; Guo, Shaodong; Ravi Kumar, Majeti N V British journal of pharmacology 2017 Apr;1742074-2084
- Cytokines and metabolic factors regulate tumoricidal T-cell function during cancer immunotherapy.
Adler, Adam J; Mittal, Payal; Ryan, Joseph M; Zhou, Beiyan; Wasser, Jeffrey S; Vella, Anthony T Immunotherapy 2017 Jan;9(1):71-82
- Roles of arginine in cell-mediated and humoral immunity
Wenkai Ren, Yulong Yin, Beiyan Zhou, Fuller W Bazer, Guoyao Wu Nutrition, Immunity & Infection 2017 Oct;
- MicroRNA-regulated immune cell function in obese adipose tissue. (Chapter 26)
Zhou B*, Ying W, Li C, Vella AT Handbook of Nutrition, Diet, and Epigenetics 2017 Jun;
- Nutrition, microRNAs, and Human Health.
Cui, Juan; Zhou, Beiyan; Ross, Sharon A; Zempleni, Janos Advances in nutrition (Bethesda, Md.) 2017 Jan;8(1):105-112
2016
- Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action.
Yang, Ence; Wang, Gang; Yang, Jizhou; Zhou, Beiyan; Tian, Yanan; Cai, James J Human molecular genetics 2016 Sep;
- Data describing the effects of dietary bioactive agents on colonic stem cell microRNA and mRNA expression.
Shah, Manasvi S; Kim, Eunjoo; Davidson, Laurie A; Knight, Jason M; Zoh, Roger S; Goldsby, Jennifer S; Callaway, Evelyn S; Zhou, Beyian; Ivanov, Ivan; Chapkin, Robert S Data in brief 2016 Mar;6398-404
- MiR-129 triggers autophagic flux by regulating a novel Notch-1/ E2F7/Beclin-1 axis to impair the viability of human malignant glioma cells.
Chen, Xiong; Zhang, Yingying; Shi, Yingying; Lian, Haiwei; Tu, Huilin; Han, Song; Yin, Jun; Peng, Biwen; Zhou, Beiyan; He, Xiaohua; Liu, Wanhong Oncotarget 2016 Jan;79222-35
- Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic crypt.
Shah, Manasvi S; Kim, Eunjoo; Davidson, Laurie A; Knight, Jason M; Zoh, Roger S; Goldsby, Jennifer S; Callaway, Evelyn S; Zhou, Beyian; Ivanov, Ivan; Chapkin, Robert S Biochimica et biophysica acta 2016 Jan;1862(1):121-34
- Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice.
Shi, Liheng; Kim, Andy Jeesu; Chang, Richard Cheng-An; Chang, Janet Ya-An; Ying, Wei; Ko, Michael L; Zhou, Beiyan; Ko, Gladys Yi-Ping PloS one 2016 Jan;11(6):e0157543
- miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Ying, Wei; Tseng, Alexander; Chang, Richard Cheng-An; Wang, Haiqing; Lin, Yu-Lieh; Kanameni, Srikanth; Brehm, Tyler; Morin, Andrew; Jones, Benjamin; Splawn, Taylor; Criscitiello, Michael; Golding, Michael C; Bazer, Fuller W; Safe, Stephen; Zhou, Beiyan Scientific reports 2016 Jan;620176
2015
- MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
Ying, Wei; Tseng, Alexander; Chang, Richard Cheng-An; Morin, Andrew; Brehm, Tyler; Triff, Karen; Nair, Vijayalekshmi; Zhuang, Guoqing; Song, Hui; Kanameni, Srikanth; Wang, Haiqing; Golding, Michael C; Bazer, Fuller W; Chapkin, Robert S; Safe, Stephen; Zhou, Beiyan The Journal of clinical investigation 2015 Nov;125(11):4149-59
- High-Fat Diet-Induced Retinal Dysfunction.
Chang, Richard Cheng-An; Shi, Liheng; Huang, Cathy Chia-Yu; Kim, Andy Jeesu; Ko, Michael L; Zhou, Beiyan; Ko, Gladys Y-P Investigative ophthalmology & visual science 2015 Apr;56(4):2367-80
- The many faces of interferon tau.
Bazer, Fuller W; Ying, Wei; Wang, Xiaoqiu; Dunlap, Kathrin A; Zhou, Beiyan; Johnson, Greg A; Wu, Guoyao Amino acids 2015 Mar;47(3):449-60
- NR4A Orphan Receptors as Drug Targets
Stephen Safe, Syng-Ook Lee, Cong Meng, Beiyan Zhou Targeted Therapy of Acute Myeloid Leukemia 2015 Jan;
- MicroRNA-regulated immune cell function in obese adipose tissue
Wei Ying, Chuan Li, Anthony T Vella, Beiyan Zhou Handbook of Nutrition, Diet, and Epigenetics
pre-2015
- Pregnancy-secreted Acid phosphatase, uteroferrin, enhances fetal erythropoiesis.
Ying, Wei; Wang, Haiqing; Bazer, Fuller W; Zhou, Beiyan Endocrinology 2014 Nov;155(11):4521-30
- MicroRNA-503 acts as a tumor suppressor in glioblastoma for multiple antitumor effects by targeting IGF-1R.
Zhang, Yingying; Chen, Xiong; Lian, Haiwei; Liu, Jianmiao; Zhou, Beiyan; Han, Song; Peng, Biwen; Yin, Jun; Liu, Wanhong; He, Xiaohua Oncology reports 2014 Mar;31(3):1445-52
- Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.
Ying, Wei; Kanameni, Srikanth; Chang, Cheng-An; Nair, Vijayalekshmi; Safe, Stephen; Bazer, Fuller W; Zhou, Beiyan PloS one 2014 Jan;9(6):e98835
- MicroRNAs Control Macrophage Formation and Activation: The Inflammatory Link between Obesity and Cardiovascular Diseases.
Chang, Richard Cheng-An; Ying, Wei; Bazer, Fuller W; Zhou, Beiyan Cells 2014 Jan;3(3):702-12
- Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression.
Triff, Karen; Konganti, Kranti; Gaddis, Sally; Zhou, Beiyan; Ivanov, Ivan; Chapkin, Robert S Physiological genomics 2013 Dec;45(24):1229-43
- miR-150 blocks MLL-AF9-associated leukemia through oncogene repression.
Bousquet, Marina; Zhuang, Guoqing; Meng, Cong; Ying, Wei; Cheruku, Patali S; Shie, Andrew T; Wang, Stephanie; Ge, Guangtao; Wong, Piu; Wang, Gang; Safe, Stephen; Zhou, Beiyan Molecular cancer research : MCR 2013 Aug;11(8):912-22
- Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation.
Li, Fen; Yu, Xuan; Szynkarski, Claudia K; Meng, Cong; Zhou, Beiyan; Barhoumi, Rola; White, Richard E; Heaps, Cristine L; Stallone, John N; Han, Guichun PloS one 2013 Jan;8(6):e64771
- Investigation of macrophage polarization using bone marrow derived macrophages.
Ying, Wei; Cheruku, Patali S; Bazer, Fuller W; Safe, Stephen H; Zhou, Beiyan Journal of visualized experiments : JoVE 2013 Jan;(76):
- A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation.
Zhuang, Guoqing; Meng, Cong; Guo, Xin; Cheruku, Patali S; Shi, Lei; Xu, Hang; Li, Honggui; Wang, Gang; Evans, Ashley R; Safe, Stephen; Wu, Chaodong; Zhou, Beiyan Circulation 2012 Jun;125(23):2892-903
- Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.
Shah, Manasvi S; Schwartz, Scott L; Zhao, Chen; Davidson, Laurie A; Zhou, Beiyan; Lupton, Joanne R; Ivanov, Ivan; Chapkin, Robert S Physiological genomics 2011 May;43(10):640-54
- MicroRNA miR-125b causes leukemia.
Bousquet, Marina; Harris, Marian H; Zhou, Beiyan; Lodish, Harvey F Proceedings of the National Academy of Sciences of the United States of America 2010 Dec;107(50):21558-63
- Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.
Ouyang, N; Ke, S; Eagleton, N; Xie, Y; Chen, G; Laffins, B; Yao, H; Zhou, B; Tian, Y British journal of cancer 2010 Jun;102(12):1753-61
- MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targets.
Le, Minh T N; Xie, Huangming; Zhou, Beiyan; Chia, Poh Hui; Rizk, Pamela; Um, Moonkyoung; Udolph, Gerald; Yang, Henry; Lim, Bing; Lodish, Harvey F Molecular and cellular biology 2009 Oct;29(19):5290-305
- MicroRNA-125b is a novel negative regulator of p53.
Le, Minh T N; Teh, Cathleen; Shyh-Chang, Ng; Xie, Huangming; Zhou, Beiyan; Korzh, Vladimir; Lodish, Harvey F; Lim, Bing Genes & development 2009 Apr;23(7):862-76
- Micromanagement of the immune system by microRNAs.
Lodish, Harvey F; Zhou, Beiyan; Liu, Gwen; Chen, Chang-Zheng Nature reviews. Immunology 2008 Feb;8(2):120-30
- Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.
Liao, Mai-Jing; Zhang, Cheng Cheng; Zhou, Beiyan; Zimonjic, Drazen B; Mani, Sendurai A; Kaba, Megan; Gifford, Ann; Reinhardt, Ferenc; Popescu, Nicholas C; Guo, Wenjun; Eaton, Elinor Ng; Lodish, Harvey F; Weinberg, Robert A Cancer research 2007 Sep;67(17):8131-8
- miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely.
Zhou, Beiyan; Wang, Stephanie; Mayr, Christine; Bartel, David P; Lodish, Harvey F Proceedings of the National Academy of Sciences of the United States of America 2007 Apr;104(17):7080-5
- Analysis of placental regulation of hematopoiesis.
Zhou, Beiyan; Linzer, Daniel I H Methods in molecular medicine 2006 Jan;122355-65
- Enhanced recovery from thrombocytopenia and neutropenia in mice constitutively expressing a placental hematopoietic cytokine.
Zhou, Beiyan; Kong, Xiangrong; Linzer, Daniel I H Endocrinology 2005 Jan;146(1):64-70
- Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation.
Zhou, Beiyan; Lum, Hillary E; Lin, Jiandie; Linzer, Daniel I H Endocrinology 2002 Nov;143(11):4281-6
- A fast, sensitive and specific method for rice dwarf virus detection by northern blot hybridization.
Yu, L; Li, Y; Gu, G; Wang, Y; Zhou, B; An, C; Chen, Z Acta virologica 1999 Dec;43(6):361-5