{"id":893,"date":"2017-01-06T11:09:11","date_gmt":"2017-01-06T16:09:11","guid":{"rendered":"https:\/\/health.uconn.edu\/dev-aging\/?page_id=893"},"modified":"2025-06-10T22:49:41","modified_gmt":"2025-06-11T02:49:41","slug":"our-research","status":"publish","type":"page","link":"https:\/\/health.uconn.edu\/aging\/our-research\/","title":{"rendered":"Our Research"},"content":{"rendered":"\n<h1>\n\t\tOur Research\n\t<\/h1>\n\t<p>Established in 1986, the Center on Aging supports a robust, nationally recognized research program focused on preventing or minimizing disability and promoting quality of life in aging adults. Our interdisciplinary and translational research develops a mechanistic understanding of disability, generates and tests innovative interventions, and trains future academic leaders in geriatrics and gerontology. Our research studies seek to develop more precise and individualized ways of maintaining function in late life by preventing mobility problems, fractures, pneumonia, and voiding and memory difficulties.<\/p>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/health.uconn.edu\/dev-aging\/wp-content\/uploads\/sites\/102\/2017\/01\/Kumbar170224b059-768x512.jpg\" alt=\"UConn Health lab coats\" title=\"UConn Health lab coats on Feb. 24, 2017. (Peter Morenus\/UConn Photo)\" \/>\n\t<p>Our faculty conduct world-class research to improve function and independence in late life, supported by a research portfolio of more than $5 million per scientist. Their research skills include clinical, translational, basic, and health outcomes\/population research. This diversity allows the Center on Aging to continually enhance its research activities by monitoring the scientific progress of many relevant research disciplines and translating those discoveries from one discipline (e.g., basic research) to another (e.g., clinical investigation). We also work to translate discoveries made at academic institutions by validating them in &#8220;real world&#8221; community settings.<\/p>\n<p><strong>Research studies conducted at the UConn Center on Aging are designed to:<\/strong><\/p>\n<ul>\n<li>Foster a better understanding of the pathophysiological mechanisms by which inflammatory and endocrine risk factors contribute to frailty and disability.<\/li>\n<li>Conduct preclinical and clinical trials intended to prevent or delay frailty and disability.<\/li>\n<li>Better understand how frailty and disability are associated with sociocultural and behavioral factors, as well as healthcare and long-term care service delivery and costs.<\/li>\n<\/ul>\n\t<h2>Be A Part of Our Healthy Aging Initiatives<\/h2>\n\t<p>To join our mailing list to learn about UConn Center on Aging, Pepper Center events, and research study opportunities, call <a href=\"tel:860-679-3043\">860-679-3043<\/a>, email Lisa Pesce at <a href=\"mailto:kenyon-pesce@uchc.edu\">kenyon-pesce@uchc.edu,<\/a> fill out the\u00a0<a href=\"https:\/\/dev-redcap.uchc.edu\/redcap\/surveys\/?s=TWY77PRPHTN8LK8X\">Recruitment Volunteer Registry form<\/a>, or scan the QR code below:<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/health.uconn.edu\/aging\/wp-content\/uploads\/sites\/102\/2025\/05\/COA-Recruitment-Volunteer-Registry-QR-code-copy.png\" alt=\"\" width=\"95\" height=\"95\" \/><\/p>\n<p>UConn Claude D. Pepper Older Americans Independence Center Recruitment Volunteer Registry, <em>IRB# 23-134-2.<\/em><\/p>\n\t<h2>Active Research Studies at the Center on Aging<\/h2>\n\t<h3><strong>Computerized Cognitive Remediation of Long COVID Symptoms in Older Adults<\/strong><\/h3>\n<p>The purpose of the present study is to help address this public health crisis by determining whether computerized &#8220;brain-training&#8221; treatment has potential for improving thinking, mood, and other aspects of day-to-day functioning in older adults with Long COVID. There are two main aims of the present study. The first aim is to simply determine the &#8220;feasibility&#8221; of using brain-training treatment in older adults with Long COVID. This includes examining whether Long COVID patients are willing to engage in the treatment and whether they find the treatment acceptable and credible. The second aim is to gather preliminary data on whether the brain-training treatment appears to improve memory, thinking, mood, and other aspects of daily functioning in older adults with Long COVID.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>Dr. Cutter Lindbergh<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:lindbergh@uchc.edu\">lindbergh@uchc.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Holly Eddy, Ph.D., LMFT-S<br \/>\nClinical Research Assistant<br \/>\n<a href=\"mailto:eddy@uchc.edu\">eddy@uchc.edu<\/a>\n\t<h3>Cognitive Remediation of Executive Deficits in Geriatric Depression<\/h3>\n<p>The purpose of this study is to test how well depressed older adults are able to complete a computerized program (Neuroflex) designed to improve certain types of &#8220;thinking&#8221; skills and whether participating in Neuroflex will improve both cognition and mood. This research is being done because usual antidepressants may not be fully effective and\/or may be associated with cognitive deficits in many older adults with depression. This leaves them vulnerable to future depressive episodes. The development of new, non-invasive treatments that may help both mood and cognitive symptoms could potentially help older adults with depression.<\/p>\n<p>The study is currently recruiting adults 55 and older who have symptoms of depression and have not been diagnosed with dementia or mild cognitive impairment. To learn more or see if you are eligible to participate, please call Frances Jaynes at <a href=\"tel:860-679-7948\">860-679-7948<\/a> or email <a href=\"mailto:jaynes@uchc.edu\">jaynes@uchc.edu<\/a>.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>David Steffens, M.D., M.H.S.<br \/>\nProfessor and Chair, Department of Psychiatry<br \/>\n<a href=\"mailto:steffens@uconn.edu\">steffens@uconn.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Jennifer Brindisi<br \/>\nClinical Research Assistant III<br \/>\n<a href=\"mailto:brindisi@uchc.edu\">brindisi@uchc.edu<\/a>\n\t<h3><strong>Connecticut Housing Engagement and Support Services (CHESS) <\/strong><\/h3>\n<p>CHESS is an initiative of the CT Department of Social Services aimed at supporting CT state residents who have experienced homelessness and chronic health issues. UConn Center on Aging serves as the evaluator of this initiative. As part of the evaluation of CHESS, UConn Center on Aging team members complete baseline, 6-month and 12-month surveys with CHESS enrollees.<\/p>\n<strong>Principal Investigators<br \/>\n<\/strong>Julie Robison, Ph.D.<br \/>\nProfessor<br \/>\n<a href=\"mailto:jrobison@uchc.edu\">jrobison@uchc.edu<\/a>\n<strong>Study Coordinators<br \/>\n<\/strong>Kate Kellett<br \/>\nClinical Research Associate<br \/>\n<a href=\"mailto:kkellett@uchc.edu\">kkellett@uchc.edu<\/a>\nAzucena Minaya<br \/>\nClinical Research Assistant 2<br \/>\n<a href=\"mailto:minaya@uchc.edu\">minaya@uchc.edu<\/a>\n\t<h3><strong>CoreQ <\/strong><strong>Nursing Home Satisfaction Survey<\/strong><\/h3>\n<p>The Connecticut Department of Social Services (DSS) has contracted with the UConn Center on Aging to collect annual satisfaction surveys, called the CoreQ, from residents and family members in every Medicaid-certified nursing home in Connecticut.<\/p>\n<p>Study team members from UConn Center on Aging will annually visit each Medicaid-certified nursing home in the state and administer the CoreQ survey to a sample of eligible nursing home residents. Additionally, a sample of nursing home resident family members or resident representatives will be surveyed.<\/p>\n<p><a href=\"https:\/\/coreq.org\/\" target=\"_blank\" rel=\"noopener\">Learn more about the CoreQ<\/a>.<\/p>\n<p>For questions, please email <a href=\"mailto:uconnnursinghomesurvey@uchc.edu\">uconnnursinghomesurvey@uchc.edu<\/a>.<\/p>\n<p><a href=\"https:\/\/health.uconn.edu\/aging\/wp-content\/uploads\/sites\/102\/2025\/04\/UConn-Center-on-Aging-CoreQ-Nursing-Homes-webinar-2025.pdf\" target=\"_blank\" rel=\"noopener\">April 1, 2025 Connecticut Nursing Home CoreQ overview webinar slides<\/a>.<\/p>\n<p><a href=\"https:\/\/health.uconn.edu\/aging\/wp-content\/uploads\/sites\/102\/2025\/04\/CoreQ-FAQs_2025-Update.pdf\" target=\"_blank\" rel=\"noopener\">FAQs about the CoreQ survey administration process<\/a>.<\/p>\n<strong>Principal Investigators<br \/>\n<\/strong>Ellis Dillon, Ph.D.<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:edillon@uchc.edu\">edillon@uchc.edu<\/a>\nJulie Robison, Ph.D.<br \/>\nProfessor<br \/>\n<a href=\"mailto:jrobison@uchc.edu\">jrobison@uchc.edu<\/a>\n<strong>Study Coordinators<br \/>\n<\/strong>Sarah Driscoll<br \/>\nClinical Research Assistant II<br \/>\n<a href=\"mailto:sdriscoll@uchc.edu\">sdriscoll@uchc.edu<\/a>\nDeb Migneault<br \/>\nClinical Research Associate II<br \/>\n<a href=\"mailto:demigneault@uchc.edu\">demigneault@uchc.edu<br \/>\n<\/a>\n\t<h3><strong>Department of Developmental Services: National Core Indicator (NCI) Survey<\/strong><\/h3>\n<p>The UConn Center on Aging study team is contracted with the Connecticut Department of Developmental Services to conduct the annual National Core Indicator Survey. The survey is designed to provide DDS with DDS participants&#8217; feedback on their experiences receiving support from the Department of Developmental Services and living their lives in the community.<\/p>\n<p>For questions, please email <a href=\"mailto:dcharles@uchc.edu\">dcharles@uchc.edu<\/a>.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>Ellis Dillon, Ph.D.<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:edillon@uchc.edu\">edillon@uchc.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Doreek Charles<br \/>\nClinical Research Associate<br \/>\n<a href=\"mailto:dcharles@uchc.edu\">dcharles@uchc.edu<\/a>\n\t<h3><strong>Hematopoietic Epigenetic Memory as a Driver of Inflammation<\/strong><\/h3>\n<p>This new study is designed to help better understand how aging remodels the immune cells in the blood and affects the response to vaccines in older individuals. Participating does not include receiving a vaccination, but rather studying the immune system as we age. Participants who enroll will come for a single study visit where medical history and physical activity questionnaires are done and a blood sample collected. Participants must be between the ages of 20-35 or 65 years old and older. Participant compensation is provided.<\/p>\n<p>Interested in learning more? <a href=\"tel:860-679-3043\">860-679-3043<\/a>.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>George Kuchel, M.D.<br \/>\nProfessor<br \/>\n<a href=\"mailto:kuchel@uchc.edu\">kuchel@uchc.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Megan Wing<br \/>\nClinical Research Assistant<br \/>\n<a href=\"mailto:wing@uchc.edu\">wing@uchc.edu<\/a>\n\t<h3>Increasing Successful Returns to Community Living From Nursing Facilities Through the Money Follows the Person Program<\/h3>\n<p>Most people living with dementia (PLWD) prefer to remain at home in the community, yet research shows that they are less likely than people without dementia to successfully return to the community following nursing facility stays. This mixed methods study, funded by the National Institute on Aging, analyzes how different factors are driving disparities for PLWD and what potential policy solutions could improve health equity for PLWD, through in-depth interviews with individuals eligible for the Money Follows the Person (MFP) program and their informal caregivers, focus groups and surveys with professionals involved in the MFP program, and statistical analysis of a large group of Connecticut Medicaid nursing facility residents.<\/p>\n<p>Study team members are interviewing eligible participants and caregivers for one-on-one interviews about returning to the community after a nursing home stay. Study team members are also conducting focus groups and key informant interviews with professionals in the MFP program.<\/p>\n<p>For questions, please email Christine Bailey at <a href=\"mailto:cbailey@uchc.edu\">cbailey@uchc.edu<\/a>.<\/p>\n<strong>Principal Investigators<br \/>\n<\/strong>Ellis Dillon, Ph.D.<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:edillon@uchc.edu\">edillon@uchc.edu<\/a>\nJulie Robison, Ph.D.<br \/>\nProfessor<br \/>\n<a href=\"mailto:jrobison@uchc.edu\">jrobison@uchc.edu<\/a>\n<strong>Study Coordinators<br \/>\n<\/strong>Christine Bailey<br \/>\nClinical Research Assistant 3<br \/>\n<a href=\"mailto:cbailey@uchc.edu\">cbailey@uchc.edu<\/a>\nDeb Migneault<br \/>\nClinical Research Associate<br \/>\n<a href=\"mailto:demigneault@uchc.edu\">demigneault@uchc.edu<\/a>\nKate Kellett<br \/>\nClinical Research Associate<br \/>\n<a href=\"mailto:kkellet@uchc.edu\">kkellet@uchc.edu<br \/>\n<\/a>\n\t<h3>Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults<\/h3>\n<p>The research is being done to determine whether a antioxidant vitamin called MitoQ improves blood flow, physical health and strength, and mental abilities of older adults.<\/p>\n<p>Call the UConn Center on Aging at <a href=\"tel:860-679-3043\">860-679-3043<\/a> to learn more.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>Oh Sung Kwon, Ph.D.<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:ohsung.kwon@uconn.edu\">ohsung.kwon@uconn.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Allison Laska<br \/>\nClinical Research Assistant<br \/>\n<a href=\"mailto:alaska@uchc.edu\">alaska@uchc.edu<\/a>\n\t<h3>Mito-LUTS: A Pilot Study of the Effect of MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome<\/h3>\n<p>Lower urinary tract symptoms (LUTS) have a high incidence, with well-documented negative effects on the quality of life of affected individuals. This study will look to see if a supplement, MitoQ, can improve bothersome bladder symptoms (including urgency, frequency, nocturia, and incontinence) that can occur with aging and metabolic syndrome.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>Iman M. Al-Naggar, Ph.D.<br \/>\nAssistant Professor<br \/>\n<a href=\"mailto:alnaggar@uchc.edu\">alnaggar@uchc.edu<\/a>\n<strong>Study Coordinator<br \/>\n<\/strong>Heather McAbee-Sevick, R.N.<br \/>\nClinical Research Assistant<br \/>\n<a href=\"mailto:mcabeesevick@uchc.edu\">mcabeesevick@uchc.edu<\/a>\n\t<h3><strong>Money Follows the Person Home and Community Based Services (HCBS) CAHPS Survey<\/strong><\/h3>\n<p>As part of the comprehensive Money Follows the Person program (MFP) quality management strategy, the UConn Center on Aging study team directly interviews participants or their representatives asking about their experiences in the year after transition through the MFP program. MFP consumers are interviewed at 1 month and 12 months post-transition to identify the quality of care and services each consumer experiences over the entirety of their time in the MFP program using the Consumer Assessment of Healthcare Providers and Systems Home and Community-Based Services (HCBS CAHPS\u00ae) survey.<\/p>\n<strong>Principal Investigator<br \/>\n<\/strong>Julie Robison, Ph.D.<br \/>\nProfessor<br \/>\n<a href=\"mailto:jrobison@uchc.edu\">jrobison@uchc.edu<\/a>\n<strong>Study Coordinators<br \/>\n<\/strong>Martha Porter<br \/>\nClinical Research Associate<br \/>\n<a href=\"mailto:porter@uchc.edu\">porter@uchc.edu<\/a>\nTherence James<br \/>\nClinical Research Assistant<br \/>\n<a href=\"mailto:tjames@uchc.edu\">tjames@uchc.edu<\/a>\n<div class=\"physician-news\"><h1>Our Research in the News<\/h1><div class=\"row\"><div class=\"post col-md-4\"><p class=\"title\"><a href=\"https:\/\/today.uconn.edu\/2025\/11\/dr-madison-doolittle-receives-american-federation-for-aging-research-grant\/\">Dr. Madison Doolittle Receives American Federation for Aging Research Grant<\/a><\/p><p class=\"content\"><\/p><p class=\"date\">November 4, 2025<\/p><\/div><div class=\"post col-md-4\"><p class=\"title\"><a href=\"https:\/\/www.courant.com\/2025\/07\/29\/uconn-researches-determine-potential-cause-of-alzheimers-disease-what-to-know\/\">UConn Researchers Determine Potential Cause of Alzheimers Disease<\/a><\/p><p class=\"content\"><\/p><p class=\"date\">July 30, 2025<\/p><\/div><div class=\"post col-md-4\"><p class=\"title\"><a href=\"https:\/\/today.uconn.edu\/2025\/03\/crisp-award-funds-study-on-immunotherapys-impact-on-cognitive-function\/\">CRISP Award Funds Study on Immunotherapy\u2019s Impact on Cognitive Function<\/a><\/p><p class=\"content\"><\/p><p class=\"date\">March 14, 2025<\/p><\/div><div class=\"clearfix\"><\/div><\/div><\/div>\n\t\t\t<a href=\"https:\/\/health.uconn.edu\/aging\/news-and-publications\" target=\"_self\" rel=\"noopener\">\n\t\t\t\t\t\t\tRead More\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":88,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-04 08:15:31","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/pages\/893"}],"collection":[{"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/users\/88"}],"replies":[{"embeddable":true,"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/comments?post=893"}],"version-history":[{"count":72,"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/pages\/893\/revisions"}],"predecessor-version":[{"id":3442,"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/pages\/893\/revisions\/3442"}],"wp:attachment":[{"href":"https:\/\/health.uconn.edu\/aging\/wp-json\/wp\/v2\/media?parent=893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}