Faculty

Hector Leonardo Aguila, Ph.D., Albert Einstein College of Medicine, Associate Professor of Immunology. Hematopoiesis and bone marrow microenvironment; lymphoid cell development; stem cell biology.

Andrew Arnold, M.D., Professor of Medicine and Genetics and Developmental Biology, Murray-Heilig Chair in Molecular Medicine. The molecular genetic underpinnings of tumors of the endocrine glands. Role of cyclin D1 in tumorigenesis.

Peter Benn, Ph.D., Director, Diagnostic Human Genetics Laboratories. Clinical cytogenetics, molecular cytogenetics and molecular genetics services. Prenatal risk evaluation through maternal serum screening.

Michael Blinov, Assistant Professor of Genetics and Developmental Biology, Ph.D., Weizmann Institute of Science. Computational Biology: Modeling of signal transcription systems and protein-dna interactions. Bioinformatics: Data mining and visualization. Developing software tools and mathematical methods for rule-based modeling of signal transduction systems.

Gordon Carmichael, Ph.D., Professor of Molecular, Microbial and Structural Biology, Regulation of gene expression in eukaryotes.

Stormy J. Chamberlain, Assistant Professor of Genetics and Developmental Biology. Ph.D., University of Florida. Human induced pluripotent stem (iPS) cell models to study 15q11-q13 imprinting disorders.

Albert Cheng, JAX_icon Assistant Professor of Genetics and Developmental Biology, Ph.D., Massachusetts Institute of Technology. Engineering and appling artificial DNA and RNA binding proteins to study the genome, epigenome, and transcriptome.

Jeffrey Chuang, JAX_icon Associate Professor, Genetics and Developmental Biology, Ph.D., Massachusetts Institute of Technology. Computational biology and bioinformatics; genomics, gene regulation, molecular evolution, and metabolomics. Post-transcriptional regulation and cancer genomics.

Kevin Claffey, Ph.D., Professor of Physiology. Angiogenesis in cancer progression and metastasis; Vascular endothelial growth factor (VEGF) expression; Hypoxia-mediated gene regulation.

Justin Cotney, Assistant Professor, Ph.D. Emory University. Determining how gene regulatory elements, namely enhancers, control gene expression during mammalian development.

Jonathan Covault, Professor of Psychiatry, M.D., Ph.D., University of Iowa. Genetic correlates of alcohol use disorders and the role of neuroactive steroids in the effects of alcohol.

Soheil (Sam) Dadras, Associate Professor of Dermatology, and Genetics and Developmental Biology, M.D.-Ph.D. Northwestern University. Discovery of small RNAs (including microRNA) as novel biomarkers in human melanoma progression and metastasis using next generation sequencing.

Asis K. Das, Professor of Molecular, Microbial and Structural Biology, B.Sc., M.Sc., Ph.D., University of Calcutta. Genetics, genomics and mechanisms of bacterial adaptive response; genetic control of bacteriophage lysogeny and lysis; and non-coding RNAs in prokaryotic development.

Caroline N. Dealy, Ph.D., Associate Professor of Biostructure and Function. The molecular regulation of limb development in the vertebrate embryo, from early stages where the limb is initially formed, to limb patterning and outgrowth, to skeletogenesis.

Paul Epstein, Associate Professor of Cell Biology; Ph.D., Albert Einstein College of Medicine. Targeting the cAMP signaling pathway for treatment of leukemia and breast cancer.

Guo-Hua Fong, Ph.D., Associate Professor of Cell Biology. Developmental biology of the vascular system, VEGF-A receptor signal transduction, embryonic stem cells and gene knock-out in mice.

Brenton R. Graveley, Ph.D., Professor of Genetics and Developmental Biology. Regulation of alternative pre-mRNA splicing.

Arthur Günzl, Ph.D., Professor of Genetics and Developmental Biology and Center for Microbial Pathogenesis. Transcription and Antigenic Variation in the mammalian parasite Trypanosoma brucei.

Marc Hansen, Ph.D., Professor of Medicine. Molecular genetics of osteosarcoma and related bone diseases.

Laura Haynes, Professor of Immunology, Ph.D., University of Rochester School of Medicine. How aging influences immune responses, especially to infectious diseases such as influenza and bacterial pneumonia. Mechanisms involved in specific age-related changes in the immune system and how these changes influence the generation of protective immunity following infection or vaccination.

J. Travis Hinson, Assistant Professor of Cardiology and Genetics, M.D., Harvard. Human iPS disease modeling of cardiovascular disorders, functional genomics, regenerative medicine related to the heart, and CRISPR/CAS9 genomewide screens in iPS-cell assays.

Laurinda Jaffe, Ph.D., Professor of Cell Biology. The cell biology of fertilization, and the regulation of meiosis in oocytes.

Barbara Kream, Ph.D., Professor of Medicine and Genetics and Developmental Biology. Hormonal regulation of bone remodeling.

George Kuchel, M.D., Professor of Medicine. Role of hormones and cytokines in geriatric disability. Pathogenesis of impaired detrusor contractility and urinary retention. Molecular mechanisms of bladder muscle survival.

Marc Lalande, Ph.D., Professor and Head of Genetics and Developmental Biology. Epigenetics including the control of gene expression in embryonic carcinoma stem cells and genomic imprinting and its association with neurogenetics disorders.

James Li, Ph.D., Associate Professor. Mechanisms underlying normal and abnormal development of the central nervous system; stem cell biology.

Alexander Lichtler, Ph.D., Associate Professor of Genetics and Developmental Biology. Regulation of collagen gene transcription; retrovirus vectors; role of homeobox genes in limb development.

Edison T. Liu, Professor, M.D., Stanford University. President and CEO The Jackson Laboratory.

Peter Maye, Assistant Professor of Reconstructive Sciences, Ph.D., Wesleyan University. Isolation, characterization and differentiation of embryonic and adult skeletal stem cells down the osteogenic lineage.

Bruce J. Mayer, Professor of Genetics and Developmental Biology, Ph.D., Rockefeller University, Mechanisms of signal transduction.

Mina Mina, D.M.D., Ph.D., Professor of Pediatric Dentistry. Characterization of genetic and epigenetic influences involved in pattern formation and skeletogenesis of the chick mandible and mouse tooth germ.

William A. Mohler, Ph.D., Associate Professor of Genetics and Developmental Biology. Developmental cell fusion; C. elegans genetics; multidimensional imaging of developmental and cell biological processes.

Julia Oh, JAX_icon Assistant Professor of Genetics and Developmental Biology, Ph.D., Stanford University. Potential of the human microbiome—the diverse bacteria, fungi, and viruses that inhabit our bodies—to deliver treatments for infectious and other diseases.

Zhengqing Ouyang, JAX_icon Assistant Professor of Genetics and Developmental Biology, Ph.D., Stanford University.  Development and application of statistical and computational methodologies in the area of regulatory genomics. Chromatin structure, lncRNA, epigenomics and epitranscriptomics, and regulatory network.

John J. Peluso, Ph.D., Professor of Cell Biology. Hormonal control of ovarian follicular growth and atresia (apoptosis); characterization of a putative membrane receptor for progesterone.

Carol C. Pilbeam, Professor of Medicine; Ph.D., Yale University, 1982. M.D., Yale School of Medicine. Mechanisms of regulation of bone formation and resorption.

Stefan Pinter, Assistant Professor of Genetics and Genomic Sciences, Ph.D., Princeton University. How chromosome topology, non-coding (nc)RNA and chromatin modifiers orchestrate gene expression.

Justin D. Radolf, M.D., Professor of Medicine and Center for Microbial Pathogenesis. Molecular pathogenesis and immunobiology of spirochetal infections.

Blanka Rogina, Associate Professor of Genetics and Developmental Biology, Ph.D., Zagreb University School of Medicine. Biology of aging including the molecular genetic determinants of aging and longevity.

Daniel W. Rosenberg, Ph.D., Professor of Medicine. Molecular genetics of colorectal cancer; signaling pathways in the development of tumors; toxicogenomics,

Edward F. Rossomando, D.D.S., Ph.D., Professor of BioStructure and Function. Control of gene expression in tumor and nontumor cell lines in response to stimulation by monokines; coding, transmission, and processing of environmental signals in normal and abnormal development.

Yijun Ruan, JAX_icon Professor, Ph.D. Elucidating the structures and dynamics of all functional DNA elements in complex genomes through DNA sequencing analysis of genetic variations in genomes and transcriptomes.

Archana Sanjay, Assistant Professor of Orthopaedic Surgery, School of Medicine, Ph.D. Regulation of bone remodeling; osteoblast and osteoclast differentiation and function.

Mansoor Sarfarazi, Ph.D., Professor of Surgery. Positional mapping and mutation analysis of human genetic disorders; primary open angle glaucoma, primary congenital glaucoma, synpolydactyly, dyslexia, mitral valve prolapse and ascending aortic aneurysm.

Michael Stitzel, JAX_icon Assistant Professor, Ph.D., Johns Hopkins University. Human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.

Duygu Ucar, JAX_icon Assistant Professor of Genetics, Ph.D., Ohio State. Developing computational models to take advantage of existing datasets to study the dynamics and mechanisms of transcriptional gene regulation and propose testable hypotheses.

Zhao-Wen Wang, Associate Professor of Neuroscience, Ph.D. Function and regulation of potassium channels and gap junctions; mechanisms of synaptic transmission.

Chia-Lin Wei, JAX_icon Director of Genome Technologies, The Jackson Laboratory for Genomic Medicine, Ph.D., University of California-Davis. Developing genomic and sequencing technologies and applying them to interrogate genomic and epigenomic elements pertinent to genome function and biology.

George Weinstock, JAX_icon Associate Director for Microbial Genomics [Professor], The Jackson Laboratory for Genomic Medicine, Ph.D., Massachusetts Institute of Technology.

Bruce White, Ph.D., Professor of Cell Biology. Control of prolactin gene expression at pretranslational level in GH3 cells; control of aromatase gene expression in ovarian and testicular tissues.

Adam Williams, JAX_icon Assistant Professor of Genetics, Ph.D., University College London.  The role of non-coding RNAs in regulating gene expression relating to immune cell function, in particular, CD4+ T cells.

George Y. Wu, Professor of Medicine; Chief, Hepatology Section, Herman Lopata Chair in Hepatitis Research; M.D./Ph.D., Albert Einstein College of Medicine. Targeted delivery of biological substances specifically to liver cells, viral hepatitis B and C, steatohepatitis, and mitochondrial damage in liver diseases. Details of HCV replication, immunocompetent rat model of HCV infection, targeted DNA delivery, and targeted transplantation of mitochondria to hepatocytes.

Yi Wu, Assistant Professor of Genetics and Developmental Biology.  Developing quantitative imaging tools that are capable of revealing dynamics of cellular signaling at high spatial and temporal resolution (biosensors), or that enable optical control of signaling proteins at precise times and subcellular locations (optogenetics).

Erin Young, Assistant Professor of Genetics and Developmental Biology, Ph.D., Kent State University. The understanding of gene x environment interactions on pain outcomes, with a particular focus on stress and injury/inflammation as environmental factors.

Ji Yu, Associate Professor of Genetics and Developmental Biology, Ph.D., University of Texas, Austin. Optical imaging technology; regulation mechanisms in dendritic RNA translation; cytoskeletal dynamics.

 

JAX_icon=The Jackson Laboratory for Genomic Medicine affliated faculty